YAMAORI Satoshi

ヤマオリサトシ | YAMAORI Satoshi

Affiliation and department：
Job title： Professor

Research field (2)： Pharmaceuticals - health and biochemistry , Clinical pharmacy

Research keywords (4)： Brain drug metabolism , fetal liver toxicity , Drug-drug interaction , Drug metabolizing enzyme

Research theme for competitive and other funds (11)：

2010 - 2012 Differentiation ofhuman iPS cells into hepatocytes and bile duct epithelial cells and application to drug development study
2008 - 2009 Preventive pharmaceutical research for the appropriate use of the principal marijuana constituent in clinical contexts
2003 - 2004 Hypnotic and antinociceptive effects of N3-substituted oxopyrimidines and their mechanism
大麻成分カンナビノイドの作用発現への内因性カンナビノイドの寄与
主要カンナビノイドの代謝的相互作用を介した毒性発現の分子機構

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Papers (51)：

Itoh H, Yamashita N, Kamijo S, Masuda K, Kato H, Yamaori S. Effects of acidic non-steroidal anti-inflammatory drugs on human cytochrome P450 4A11 activity: Roles of carboxylic acid and a sulfur atom in potent inhibition by sulindac sulfide. Chem Biol Interact. 2023. 382. 110644-110644
岩本大紀, 井出貴之, 三村享, 土屋広行, 山折大. 多発性骨髄腫におけるダラツムマブ点滴静注初回投与時のinfusion reaction発現に関する後方視的検討. 日本病院薬剤師会雑誌. 2022. 58. 1. 61-66
Matuso J, Yamaori S. Detecting drug-drug interactions that increase the incidence of long QT syndrome using a spontaneous reporting system. J Clin Pharm Ther. 2022. 47. 1. 70-80
Shiozawa A, Yamaori S, Kamijo S, Ohmori S. Effects of acid and lactone forms of statins on S-warfarin 7-hydroxylation catalyzed by human liver microsomes and recombinant CYP2C9 variants (CYP2C9.1 and CYP2C9.3). Drug Metab Pharmacokinet. 2021. 36. 100364
Ozawa S, Yamaori S, Aikawa K, Kamijo S, Ohmori S. Expression profile of cytochrome P450s and effects of polycyclic aromatic hydrocarbons and antiepileptic drugs on CYP1 expression in MOG-G-CCM cells. Life Sci. 2020. 258. 118140

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MISC (5)：

Books (2)：

衛生薬学-健康の維持と増進をめざして-
京都廣川書店 2023 ISBN:9784910844091
Cannabinoids as potent inhibitors of human CYP1 enzymes
In: Preedy VR, editor. Handbook of Cannabis and Related Pathologies: Biology, Diagnosis, Treatment and Pharmacology 2017

Lectures and oral presentations (7)：

ヒトCYP4F2の機能に対するアゾール系抗真菌薬の影響
(日本薬学会第140年会 2020)
妊婦に関連するNSAIDs含有貼付剤の添付文書記載内容と胎児動脈管収縮に関連した副作用報告の実態調査
(日本薬学会第140年会 2020)
ヒトCYP2J2活性に対する降圧薬の阻害効果
(日本薬物動態学会第34回年会 2019)
SGLT2阻害薬の上乗せ効果と肝機能検査値改善に影響を及ぼす因子の解析
(第29回日本医療薬学会年会 2019)
SGLT2阻害薬の血糖降下作用と肝機能検査値改善に影響を与える患者背景の検証
(第8回日本くすりと糖尿病学会学術集会 2019)

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Education (4)：

2000 - 2002 Hokkaido University Graduate School of Pharmaceutical Sciences
1998 - 2000 Hokkaido University Graduate School of Pharmaceutical Sciences Master Course
1995 - 1998 Hokkaido University Faculty of Pharmaceutical Sciences
1994 - 1995 Hokkaido University

Professional career (1)：

Work history (5)：

2021/04 - 現在 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
2012/04 - 2021/03 Shinshu University Shinshu University Hospital Department of Pharmacy
2007/10 - 2012/03 Hokuriku University Faculty of Pharmaceutical Sciences
2008/08 - 2009/08 NIH NCI
2002/10 - 2007/09 Hokuriku University Faculty of Pharmaceutical Sciences

Awards (2)：

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