Rchr
J-GLOBAL ID:200901091771912340   Update date: Mar. 24, 2024

Nakata Hirotomo

ナカタ ヒロトモ | Nakata Hirotomo
Affiliation and department:
Research field  (1): Infectious disease
Research keywords  (4): 抗HIV薬 ,  感染制御 ,  感染症 ,  HIV
Research theme for competitive and other funds  (5):
  • 2022 - 2025 HIV感染におけるケモカイン受容体の動態解析とその多量体形成を標的とした薬剤開発
  • 2021 - 2024 HIV関連神経認知障害(HAND)診断ツールの標準値構築と動作エラーモデルの開発
  • 2018 - 2022 Development of screening measures for detection of HIV-associated neurocognitive disorders (HAND)
  • 2018 - 2021 Elucidation of the mechanism of HIV entry step and the development of novel anti-HIV drug through the analysis of the inhibitory effects on the oligomerization of the chemokine receptors
  • 2014 - 2017 A study of chemokine receptor dynamics and its inhibitor(s) in HIV infection
Papers (45):
  • Tomofumi Nakamura, Mayu Okumura, Nobutoki Takamune, Tatsunori Hirotsu, Masaharu Sugiura, Junichiro Yasunaga, Hirotomo Nakata. Conversion of raltegravir carrying a 1,3,4-oxadiazole ring to a hydrolysis product upon pH changes decreases its antiviral activity. PNAS nexus. 2024. 3. 1. pgad446
  • Kazutaka Oda, Ayami Yamaguchi, Naoya Matsumoto, Hirotomo Nakata, Yusuke Higuchi, Kisato Nosaka, Hirofumi Jono, Hideyuki Saito. Dose Individualization of Cefepime for Febrile Neutropenia in Patients With Lymphoma or Multiple Myeloma: Implications for Therapeutic Drug Monitoring. Therapeutic drug monitoring. 2023
  • Hiro Tatetsu, Yusuke Higuchi, Takafumi Shichijo, Kazutaka Oda, Hirotomo Nakata, Jun-Ichirou Yasunaga, Kisato Nosaka, Masao Matsuoka. Prophylactic effect of tixagevimab-cilgavimab on COVID-19 infection and death in Japanese patients with B cell lymphoma. International journal of hematology. 2023
  • Kaho Matsumoto, Takeo Kuwata, William D Tolbert, Jonathan Richard, Shilei Ding, Jérémie Prévost, Shokichi Takahama, George P Judicate, Takamasa Ueno, Hirotomo Nakata, et al. Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates. Journal of virology. 2023. 97. 1. e0163822
  • 野坂 生郷, 立津 央, 樋口 悠介, 七條 敬文, 尾田 一貴, 中田 浩智, 安永 純一朗, 松岡 雅雄. B細胞リンパ腫に対してのチキサゲビマブーシルガビマブのCOVID-19発症及び重症化抑制効果. 日本血液学会学術集会. 2022. 84回. 65-65
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MISC (44):
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Lectures and oral presentations  (7):
  • 1,3,4-oxadiazole環を有するRaltegravirは強酸性下で加水分解され、抗HIV活性が低下する
    (日本エイズ学会誌 2023)
  • CXCR4多量体形成が関連したHIV-1感染機序の解明
    (日本エイズ学会誌 2023)
  • AST活動におけるHow toを共有しよう 熊本大学病院におけるAST活動
    (日本化学療法学会雑誌 2023)
  • B細胞リンパ腫に対してのチキサゲビマブーシルガビマブのCOVID-19発症及び重症化抑制効果
    (日本血液学会学術集会 2022)
  • ダプトマイシン低感受性化およびリネゾリド耐性化に至ったMRSAによる感染性大動脈瘤感染症難治例の1例
    (日本化学療法学会雑誌 2022)
more...
Professional career (1):
  • PhD (Kumamoto University)
Work history (1):
  • 旧所属 熊本大学 大学院医学研究科
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