Research field (2)：
Immunology
, Pharmaceuticals - health and biochemistry
Research theme for competitive and other funds (11)：
2016 - 2019 Study of lipsomal vaccine entrapping MHC-binding peptides for production of secretory IgA against Shiga-like toxin B subunit
2015 - 2018 Studies on the efficacy of toxin neutralization and safety of Shiga toxin-specific secretory IgA type plantibody produced by practical plants
2015 - 2017 Studies on adjuvant chemicals predicted by activation of a nociceptive receptor TRPA1
2013 - 2015 Mucosal surface defense by edible IgA produced by plants
2011 - 2014 Adjuvant effect of chemicals on contact hypersensitivity through transient receptor potential channels
2011 - 2012 Expression of secretory immunoglobulin A in lettuce suitable for the production of therapeutic antibodies in plantfactory.
2009 - 2010 Production of secretory IgA against Shiga-like toxin B subunit using liposomes entrapping MHC-binding peptides
2008 - 2010 Adjuvant effect mechanism on contact sensitization through nociceptive receptors
2007 - 2008 Induction of mucosal immunity using liposomes entrapping MHC-binding peptides
2006 - 2007 接触感作促進作用を有する化学物質の侵害刺激受容チャネルに対する効果
2004 - 2005 Production of IgA using nasal associated lymphoid tissues toward development of therapeutic antibodies for oral administration.
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Papers (52)：
Akimasa Orii, Kohta Kurohane, Kota Sekiguchi, Masato Tsutsumi, Yasuyuki Imai. Comparison of adjuvant mechanisms of medium-chain triacylglycerol in a mouse FITC-induced contact hypersensitivity model. Toxicology. 2023. 488. 153482-153482
Katsuhiro Nakanishi, Taichi Takase, Yuya Ohira, Ryota Ida, Noriko Mogi, Yuki Kikuchi, Minami Matsuda, Kohta Kurohane, Yoshihiro Akimoto, Junri Hayakawa, et al. Prevention of Shiga toxin 1-caused colon injury by plant-derived recombinant IgA. Scientific Reports. 2022. 12. 1. 17999-17999
Sumalee Panthong, Yasuyuki Imai, Takeshi Matsuoka, Wakana Suzuki, Tatsuo Watanabe, Yuko Terada, Kohta Kurohane, Kota Sekiguchi, Erina Ogawa, Yukina Endo, et al. The role of Piper chaba Hunt. and its pure compound, piperine, on TRPV1 activation and adjuvant effect. BMC complementary medicine and therapies. 2020. 20. 1. 134-134
丸尾遥佳, 黒羽子孝太, 織井亮匡, 野瀬睦, 木川晶峻, 今井康之. Comparison of adjuvant mechanisms of triacylglycerols with different fatty acid chain lengths in an FITC-induced contact hypersensitivity. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
茂木典子, 中西勝宏, 黒羽子孝太, 菊地祐希, 松田弥奈美, 森兼捷太, 丹羽康夫, 小林裕和, 今井康之. Digestive enzyme resistance of secretory IgA is created by plant-derived secretory component in vitro. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
木川晶峻, 黒羽子孝太, 織井亮匡, 野瀬睦, 丸尾遥佳, 今井康之. Study on suppressive mechanisms of mouse contact hypersensitivity by triolein comprised of a long-chain unsaturated fatty acid. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
高瀬太一, 大平裕也, 中西勝宏, 黒羽子孝太, 今井康之. Effect of oral administration of leukotriene C4 on sensitivity to Shiga toxin 1 in mice. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM
, THE JAPANESE SOCIETY FOR IMMUNOLOGY
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, 日本免疫毒性学会
, 日本抗体学会
, 日本薬学教育学会
, 日本香粧品学会
