Rchr
J-GLOBAL ID：200901097584385652   Update date: Apr. 24, 2024

TANABE Shihori

タナベ シホリ | TANABE Shihori
Affiliation and department：
National Institute of Health Sciences

About National Institute of Health Sciences


Job title： Senior Researcher
Research field  (2)： Pharmaceuticals - health and biochemistry ,  Biological, health, and medical informatics
Research keywords  (7)： Epithelial mesenchymal transition ,  Gene expression ,  Stem cell ,  Cancer ,  Molecular network pathway ,  Pharmaceutical science ,  Molecular cellular biology
Research theme for competitive and other funds  (7)：
  • 2021 - 2024 Study of molecular network pathway analysis on prediction and risk assessment of pharmaceutics
  • 2021 - 2024 Elucidation on regulation mechanism of RNA viral infection molecular network in diffuse- and intestinal-type gastric cancer
  • 国際機関安全情報に関する研究
  • 細胞治療薬に関する研究
  • Network analysis of exosome RNA and gene expression in silico
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Papers (106)：
  • Shihori Tanabe. Advances in Molecular Mechanisms of Gastrointestinal Tumors. Cancers. 2024. 16. 8. 1603
  • Amgad Abdallah, Nada Adel, Am El Kerdawy, Shihori Tanabe, Frédéric Andrès, Andreas Pester, Hesham H. Ali. Geom-SAC: Geometric multi-discrete soft actor critic with applications in de novo drug design. IEEE Access. 2024. 12. 45519-45529
  • Amgad A. Mahmoud, Nada A. Alyan, Ahmed M. El Kerdawy, Shihori Tanabe, Frédéric Andrès, Andreas Pester, Hesham H. Ali. A New Graph-Based Reinforcement Learning Environment for Targeted Molecular Generation and Optimization. ICSIE '23: Proceedings of the 2023 12th International Conference on Software and Information Engineering. 2024. November 2023. 52-57
  • Shihori Tanabe. Role of eIF2 signaling in cancer and its relationship with coronavirus. Advances in Clinical and Medical Research. 2024. 5. 1. 1-3
  • Maranda Esterhuizen, Chang-Beom Park, Young Jun Kim, Tae-Young Kim, Hakwon Yoon, Frederic Andres, Rosalia Rodriguez-Rodriguez, Shihori Tanabe. A Perspective on the Role of Physiological Stresses in Cancer, Diabetes and Cognitive Disease as Environmental Diseases. Frontiers in Molecular Biosciences. 2023. 10. 1274221
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MISC (26)：
  • Shihori Tanabe, Sabina Quader, Ryuichi Ono, Horacio Cabral, Kazuhiko Aoyagi, Akihiko Hirose, Edward J Perkins, Hiroshi Yokozaki, Hiroki Sasaki. Artificial Intelligence-Based Models to Predict the Activation State of Molecular Pathway in Diseases. The 37th Annual Conference of the Japanese Society for Artificial Intelligence, 2023. 2023. 2U1-IS-1b-04
  • Shihori Tanabe, Sabina Quader, Ryuichi Ono, Horacio Cabral, Kazuhiko Aoyagi, Akihiko Hirose, Edward J Perkins, Hiroshi Yokozaki, Hiroki Sasaki. The development of AOP298 "Increases in cellular reactive oxygen species leading to human treatment-resistant gastric cancer". The Journal of Toxicological Sciences. 2023. 48. Suppl. S77-S77
  • 田邊思帆里, カデール サビーナ, 小野竜一, カブラル オラシオ, 青柳一彦, 広瀬明彦, 横崎宏, 佐々木博己. がん幹細胞分子ネットワークにおける微小環境RNA制御. 日本再生医療学会総会(Web). 2023. 22nd
  • 田邊思帆里, カデール サビーナ, 小野竜一, カブラル オラシオ, 青柳一彦, 広瀬明彦, 横崎宏, 佐々木博己. The master regulators of causal networks in intestinal- and diffuse-type gastric cancer. 日本癌学会学術総会抄録集(Web). 2023. 82nd
  • 田邊思帆里, QUADER Sabina, 小野竜一, CABRAL Horacio, 青柳一彦, 広瀬明彦, 横崎宏, 佐々木博己. The relationship between coronavirus pathogenesis pathway and EIF2 signaling. 日本薬学会年会要旨集(Web). 2023. 143rd
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Books (8)：
  • Abnormal Glycosylation in Cancer Cells and Cancer Stem Cells as a Therapeutic Target
    Springer 2023 ISBN:9783031129742
  • Microenvironment of Cancer Stem Cells
    Springer 2023 ISBN:9783031129742
  • Epithelial-Mesenchymal Transition and Cancer Stem Cells
    Springer 2023 ISBN:9783031129742
  • Adverse Outcome Pathways in reproductive and developmental toxicology
    Elsevier Inc./Academic Press 2022 ISBN:9780323897730
  • Introductory Chapter: Invitation for Peripheral Membrane Proteins
    InTech 2018 ISBN:9781789235135
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Lectures and oral presentations  (138)：
  • Development of AOPs related to epithelial-mesenchymal transition (EMT) network alteration induced by gene expression dynamism and coronavirus
    (The 144th Annual Meeting of the Pharmaceutical Society of Japan 2024)
  • Updates on Guide for Coaches
    (SKIG meeting 2024)
  • Regulatory mechanism of molecular networks related to cancer stem cells
    (The 23rd Congress of the Japanese Society for Regenerative Medicine 2024)
  • Causal networks in intestinal- and diffuse-type stomach adenocarcinoma and the relation to RNA virus infection
    (The 63rd Annual Meeting of the Society of Toxicology 2024 2024)
  • An approach for applying ChatGPT in AOP development, and umbrella KEs related to the Mystery of ROS
    (SKIG meeting 2024)
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Education (4)：
  • 2000 - 2005 The University of Tokyo Graduate School of Pharmaceutical Sciences
  • 2002 - 2004 University of Illinois at Chicago College of Medicine Department of Pharmacology
  • 1998 - 2000 The University of Tokyo Faculty of Pharmaceutical Sciences
  • 1996 - 1998 The University of Tokyo Faculty of General Education Science II
Professional career (1)：
  • PhD (University of Tokyo)
Work history (6)：
  • 2016/04 - 現在 National Institute of Health Sciences Division of Risk Assessment, Center for Biological Safety and Research Senior Researcher
  • 2011/04 - 2016/03 National Institute of Health Sciences Director for Planning and Coordination’s In Concurrent
  • 2010/04 - 2016/03 National Institute of Health Sciences Division of Safety Information on Drug, Food and Chemicals Senior Researcher
  • 2009/04 - 2010/09 Ministry of Health, Labour and Welfare Health Sciences Division, Minister’s Secretariat In Concurrent
  • 2006/02 - 2010/03 National Institute of Health Sciences Division of Cellular and Gene Therapy Products Researcher
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Committee career (25)：
  • 2022/05 - 現在 Special Issue "Advances in Molecular Mechanisms of Gastrointestinal Tumors" Guest Editor
  • 2022/05 - 現在 Frontiers in Oncology - Molecular and Cellular Oncology Associate Editor
  • 2021/04 - 現在 Advances In Clinical And Medical Research Editor-in-Chief
  • 2020 - 現在 CIAO (Modelling the Pathogenesis of COVID-19 Using the Adverse Outcome Pathway Framework) Member
  • 2020 - 現在 OECD AOP Development External Review Subgroup Co-lead
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Awards (1)：
  • 2002 - 病態代謝研究会 第34回海外留学補助金
Association Membership(s) (13)：
THE JAPANESE SOCIETY FOR ARTIFICIAL INTELLIGENCE ,  JAPANESE SOCIETY OF FOOD CHEMISTRY ,  THE JAPANESE SOCIETY OF TOXICOLOGY ,  SOCIETY FOR REGULATORY SCIENCE OF MEDICAL PRODUCTS ,  JAPAN HUMAN PROTEOME ORGANISATION ,  THE JAPANESE CANCER ASSOCIATION ,  JAPANESE SOCIETY FOR CHEMICAL BIOLOGY ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  Society of Toxicology
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