Art

J-GLOBAL ID：201702228156848002   Reference number：17A0140856

Evaluation Report on an Alternative Test Method for Skin Sensitization: ARE-Nrf2 Luciferase Test

皮膚感作性試験ARE-Nrf2 Luciferase Test Method角化細胞株レポーターアッセイ評価報告書

Author (7)： TSUTSUI NAOHISA (田辺三菱製薬) ,  ADACHI REIKO (医薬品食品衛生研) ,  KANAZAWA YUKIKO (食品薬品安全セ) ,  KOJIMA KOICHI (食品薬品安全セ) ,  SATO KAZUHIRO (福井大) ,  TAKEYOSHI MASAHIRO (化学物質評価研究機構) ,  MORIMOTO TAKASHI (住友化学工業)
Material： AATEX-JaCVAM  (AATEX JaCVAM)
Volume： 5  Issue： 1  Page： 1-11  Publication year： Nov. 30, 2016 
JST Material Number： F1276A  ISSN： 2187-3690  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *sensitization(immunology) ,...
Semi thesaurus term： *Skin sensitization ,...

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JST classification (2)： Bioassay  (EA03060N) ,  Research methods in biophylaxis and immune systems  (ED01020Q)

Reference (10)：

• OECD ENV/JM/MONO (2012)/Part 1, The adverse outcome pathway for skin sensitization initiated by covalent binding to proteins: Scientific evidence.
• EURL ECVAM (2012) ESAC Working Group Peer Review Consensus Report on Givaudan-coordinated study transferability and reliability of the KeratinoSens assay for skin sensitisation testing
• OECD (2014) Performance Standards for the assessment of proposed similar or modified in vitro skin sensitization ARE-Nrf2 luciferase test methods in TG xxx. OECD Environment, Health and Safety publications, Series on Testing and Assessment N.213, OECD, Paris.
• OECD (2015) In Vitro Skin Sensitization: ARE-Nrf2 Luciferase Test Method, OECD Guidelines for the Testing of Chemicals No. 442D.
• DB-ALM (INVITTOX) (2013) Protocol 155: KeratinoSens^TM

Terms in the title (9)： 皮膚 ,  感作性試験 ,  ARE ,  NRF2 ,  角化 ,  細胞株 ,  レポーターアッセイ ,  評価 ,  報告書