Rchr
J-GLOBAL ID:201401019560014598
Update date: Apr. 02, 2024
Nishi Eiichiro
ニシ エイイチロウ | Nishi Eiichiro
Affiliation and department:
Research field (3):
Pharmacology
, Pathobiochemistry
, Internal medicine - General
Research theme for competitive and other funds (32):
- 2020 - 2023 多機能プロテアーゼによる血小板産生機構と急性冠症候群における意義
- 2020 - 2023 Investigation of the mechanisms by which Multifaceted Homeostasis is maintained by Nardilysin
- 2020 - 2022 Mechanism of protein secretion by physical stimuli (turbulent) and its physiological significance
- 2019 - 2022 A metalloprotease regulates the activity of the nuclear receptor REV-ERBs
- 2018 - 2021 Serum biomarkers affecting energy metabolism and body composition in Crohn's disease
- 2018 - 2020 新規肝栄養センサー分子による熱産生制御ネットワークの検討
- 2017 - 2020 Investigation on the homeostatic regulation by NRDC-p53 axis
- 2016 - 2019 A metalloprotease regulates the circadian clock
- 2016 - 2019 Elucidation of the mechanisms of neoatherosclerosis and degenerative vascular disease and development of novel therapeutic strategy
- 2016 - 2018 Investigation of the transcriptional coregulator involved in crosstalk between histone acetylation and methylation
- 2015 - 2017 Nardilysin regulates sinus automaticity through transcription of HCN.
- 2014 - 2017 Investigation of the multifaceted roles of nardilysin in homeostatic maintenance
- 2014 - 2016 エネルギー代謝と転写制御をつなぐ新規ヒストンコードリーダーに関する研究
- 2014 - 2016 Regulatory role of a histone-binding peptidase in inflammatory diseases
- 2013 - 2016 Elucidation of the mechanism of neoatherosclerosis
- 2013 - 2015 Assessment of temperature compensation of circadian rhythm by using cold-blooded mice
- 2012 - 2014 Nardilysin prevents amyloid plaque formation by enhancing alpha-secretase activity in an Alzheimer's disease mouse model.
- 2011 - 2014 Analysis of maternal recognition through embryo-specific sugar antigen and its inducing mechanisms for embryo implantation and placentation
- 2011 - 2014 Pathophysiological roles of nardilysin, critical factor for axonal maturation and myelination
- 2011 - 2013 細胞外ドメインシェディングによるシグナル伝達制御の病態における意義
- 2011 - 2012 Molecular Mechanism of Unconventional Secretory Pathway for "Leaderless" Proteins
- 2010 - 2010 免疫系による発生初期胚の認識機構-透明帯を利用した哺乳類の着床誘導戦略の証明-
- 2008 - 2010 Analysis of tissue remodeling mechanisms by circulating blood cells during human reproduction
- 2008 - 2010 Identification of NRDc, a novel key molecule for energy metabolism. Pathophysiological role of NRDc in Metabolic Syndrome
- 2008 - 2010 The role of nardilysin in body temperature homeostasis
- 2008 - 2008 体温による生体防御反応の制御機構:変温マウスを用いた解析
- 2007 - 2008 Analysis of molecular mechanisms and further development of a new therapy for infertile patients with repeated implantation failure using autologous peripheral blood mononuclear cells
- 2007 - 2008 肺細菌感染症における宿主膜タンパク質シェディング誘導の病態生理学的意義の解明
- 2006 - 2007 A novel molecular mechanism for ectodomain shedding
- 2006 - 2007 Analysis of mechanisms fix human embryo implantation by crosstalk between mother and embryo through endocrine and immune system network
- 2004 - 2005 Biological significances of metalloproteases which specific ally bind to membrane-anchored growth factors
- 2004 - 2005 Molecular biological analysis of mechanisms for human embryo implantation and placentation-from the perspectrives of repulsive force, chemoattractants and membrane-bound peptidases
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Papers (75):
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Kenji Nakatsuma, Neiko Ozasa, Mikiko Ohno, Hiroshi Ishiguro, Manabu Minami, Eiichiro Nishi, Masakazu Toi, Koh Ono, Takeshi Kimura. Subclinical myocardial damage after anthracycline chemotherapy in Japanese patients with breast Cancer. Journal of Cardiology. 2024
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Satsuki Takashima, Eiichi Okamura, Yusuke Ichiyama, Kiyoto Nishi, Akio Shimizu, Chisato Watanabe, Masanaga Muto, Shoma Matsumoto, Setsuko Tsukiyama-Fujii, Tomoyuki Tsukiyama, et al. Null mutation of exocyst complex component 3-like does not affect vascular development in mice. Experimental animals. 2023
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Issei Tomita, Hiroaki Tsuruta, Mako Yasuda-Yamahara, Kosuke Yamahara, Shogo Kuwagata, Yuki Tanaka-Sasaki, Masami Chin-Kanasaki, Yukihiro Fujita, Eiichiro Nishi, Hideki Katagiri, et al. Ketone bodies: A double-edged sword for mammalian life span. Aging cell. 2023. e13833
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Akihiko Yamaguchi, Toshifumi Takahashi, Takeshi Kato, Toshihiro Tanaka, Eiichiro Nishi, Noriki Fujimoto. Immunohistochemical and clinicopathological study regarding nardilysin on extramammary Paget's disease. Archives of dermatological research. 2023. 315. 7. 1979-1987
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Shu-Yang Li, Yoichi Yoshida, Masaaki Kubota, Bo-Shi Zhang, Tomoo Matsutani, Masaaki Ito, Satoshi Yajima, Kimihiko Yoshida, Seiichiro Mine, Toshio Machida, et al. Utility of atherosclerosis-associated serum antibodies against colony-stimulating factor 2 in predicting the onset of acute ischemic stroke and prognosis of colorectal cancer. Frontiers in cardiovascular medicine. 2023. 10. 1042272-1042272
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MISC (148):
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大野美紀子, 西清人, 大林徹也, 西英一郎. ナルディライジン酵素活性の生体内における意義. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2022. 27th
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西清人, 岩崎広高, 大野美紀子, 西英一郎. 肝細胞のナルディライジンは褐色脂肪組織の熱産生を制御する. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2022. 27th
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平岡 義範, 古市 真唯, 鎌田 真由子, 斉藤 沙樹, 久米 典昭, 吉種 光, 深田 吉孝, 池田 正明, 西 英一郎. ナルディライジンによる核内受容体ROR/REV-ERB活性調節機構. 日本薬学会年会要旨集. 2021. 141年会. 27P02-137
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西 英一郎. 急性冠症候群の超早期診断および発症予知を可能にするバイオマーカー開発に関する研究. 医科学応用研究財団研究報告. 2021. 38. 473-477
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大野美紀子, 松浦博, 牧山武, 糀谷泰彦, 西清人, 松田真太郎, 木村剛, 西英一郎. NRDC regulates sinus automaticity through transcriptional regulation of ionchannels. 日本循環薬理学会口演要旨集. 2021. 31st
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Patents (4):
Books (8):
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創薬研究者・アカデミア研究者が知っておくべき最新の免疫学とその応用技術
技術情報協会 2021 ISBN:4861048567
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がん基盤生物学 -革新的シーズ育成に向けて-
南山堂 2013
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Nardilysin (MS: 328)
The Handbook of Proteolytic Enzymes (The 3rd Edition), 20 Dec 2012 Edited by Neil D. Rawlings and Guy Salvesen Academic Press 2012
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心臓血管外科Knack & Pitfalls、冠動脈外科の要点と盲点(第2版)
文光堂 2012
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健康長寿大事典ーEBMからQOLまでー
西村書店 2012
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Professional career (1):
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