Rchr
J-GLOBAL ID：201401072103921464   Update date: Apr. 04, 2024

Karasawa Tadayoshi

カラサワ タダヨシ | Karasawa Tadayoshi
Affiliation and department：
Jichi Medical University School of Medicine

About Jichi Medical University School of Medicine


Homepage URL  (1)： http://kaken.nii.ac.jp/d/r/60631893.ja.html
Research field  (2)： Cell biology ,  Metabolism and endocrinology
Research keywords  (7)： 凝集体 ,  Regulated cell death ,  脂肪酸 ,  リポタンパク質 ,  動脈硬化 ,  脂質代謝 ,  炎症
Research theme for competitive and other funds  (11)：
  • 2021 - 2024 Role and Mechanism of a novel E3 ligase ARIH2 in Cardiovascular Disease
  • 2021 - 2024 動脈硬化病変におけるカスパーゼ11依存的パイロトーシスの役割の解明
  • 2019 - 2022 Mechanism of NLRP3 inflammasome in CAWS-induced vasculitis
  • 2018 - 2022 Role of ARIH2 in the inflammasome-related cardiovascular disease
  • 2016 - 2020 Role of adapter molecule ASC independent of inflammasome
Show all
Papers (74)：
  • Naoya Yamada, Tadayoshi Karasawa, Junya Ito, Daisuke Yamamuro, Kazushi Morimoto, Toshitaka Nakamura, Takanori Komada, Chintogtokh Baatarjav, Yuma Saimoto, Yuka Jinnouchi, et al. Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis. Nature communications. 2024. 15. 1. 2195-2195
  • Fumitake Usui-Kawanishi, Koudai Kani, Tadayoshi Karasawa, Hiroe Honda, Nobuyuki Takayama, Masafumi Takahashi, Kiyoshi Takatsu, Yoshinori Nagai. Isoliquiritigenin inhibits NLRP3 inflammasome activation with CAPS mutations by suppressing caspase-1 activation and mutated NLRP3 aggregation. Genes to cells : devoted to molecular & cellular mechanisms. 2024
  • Hazuki Tanaka, Ren Ozawa, Yuka Henmi, Manabu Hosoda, Tadayoshi Karasawa, Masafumi Takahashi, Hironori Takahashi, Hisataka Iwata, Takehito Kuwayama, Koumei Shirasuna. Gasdermin D regulates soluble fms-like tyrosine kinase 1 release in macrophages. Reproductive biology. 2024. 24. 1. 100857-100857
  • Tadayoshi Karasawa, Takanori Komada, Chintogtokh Baatarjav, Emi Aizawa, Yoshiko Mizushina, Kenta Fujimura, Yoshitaka Gunji, Satoko Komori, Hidetoshi Aizawa, Cantona Billton Jing Tao, et al. Caspase-11 deficiency attenuates neutrophil recruitment into the atherosclerotic lesion in apolipoprotein E-deficient mice. Biochemical and biophysical research communications. 2023. 686. 149158-149158
  • Kenta Fujimura, Tadayoshi Karasawa, Takanori Komada, Naoya Yamada, Yoshiko Mizushina, Chintogtokh Baatarjav, Takayoshi Matsumura, Kinya Otsu, Norihiko Takeda, Hiroaki Mizukami, et al. NLRP3 inflammasome-driven IL-1β and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy. Journal of molecular and cellular cardiology. 2023. 180. 58-68
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MISC (15)：
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Patents (1)：
Education (3)：
  • 2008 - 2012 University of Tsukuba
  • 2006 - 2008 University of Tsukuba
  • 2002 - 2006 University of Tsukuba
Work history (3)：
  • 2020/04 - 現在 自治医科大学 分子病態治療研究センター 炎症・免疫研究部 講師
  • 2014/04 - 現在 Jichi Medical University School of Medicine
  • 2012/04 - 2014/03 Jichi Medical University School of Medicine
Association Membership(s) (4)：
JAPAN ATHEROSCLEROSIS SOCIETY ,  日本脂質生化学会 ,  日本分子生物学会 ,  日本Cell death学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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