Research theme for competitive and other funds (8)：
2020 - 2023 Exploring new pathway for the regulation of hepatic gluconeogenesis via microRNAs
2017 - 2021 Reduction of hepatic cholesterol synthesis is associated with hepatic glucose production
2014 - 2018 Myeliod specific inhibition of cholesterol synthesis ameliorates insulin sensitivity and hepatic steatosis.
2013 - 2016 Development of a novel therapy for atherosclerosis based on alleviation of lipotoxicity of macrophages
2012 - 2015 The roles of hepatic lipoprotein lipase and its regulating factors on the hepatic lipotoxicity
2006 - 2008 The role of macrophage lipoprotein lipase on the development of atherosclerosis
2006 - 2007 脂肪細胞内lipolysisの分子機構
2005 - 2007 Elucidation of novel functions of cholesterol and its metabolites using genetic manipulation in mice
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Papers (8)：
Sakai, Kent, Nagashima, Shuichi, Wakabayashi, Tetsuji, Tumenbayar, Bayasgalan, Hayakawa, Hiroko, Hayakawa, Morisada, Karasawa, Tadayoshi, Ohashi, Ken, Yamazaki, Hisataka, Takei, Akihito, et al. Myeloid HMG-CoA (3-Hydroxy-3-Methylglutaryl-Coenzyme A) Reductase Determines Atherosclerosis by Modulating Migration of Macrophages. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018. 38. 11. 2590-2600
Manabu Takahashi, Hiroaki Yagyu, Fumiko Tazoe, Shuichi Nagashima, Taichi Ohshiro, Kenta Okada, Jun-Ichi Osuga, Ira J. Goldberg, Shun Ishibashi. Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity. Journal of Lipid Research. 2013. 54. 4. 1124-1134
