Rchr
J-GLOBAL ID:201401096766542960   Update date: Apr. 23, 2024

Hibi Makoto

Hibi Makoto
Affiliation and department:
Research field  (2): Applied biofunctional and bioprocess engineering ,  Applied microbiology
Research keywords  (4): 応用微生物学 ,  Bioprocess ,  Enzyme Catalyst ,  Microbial Screening
Research theme for competitive and other funds  (18):
  • 2022 - 2025 Elucidation of the reaction mechanism of a novel non-heme diiron enzyme, alpha-aminoisobutyrate hydroxylase, and its application
  • 2017 - 2022 Development of soluble expression technology and utilization of enzymes from plants and animals
  • 2019 - 2022 タンデム酵素反応による(+)-アリイン生産バイオプロセスの実用化検討と応用展開
  • 2017 - 2020 Synthesis of nitrogen-containing useful compounds with the enzymes modified based on their reaction mechanisms
  • 2016 - 2018 Development of novel microbial oxidation-reduction/electron transferring function acting under high temperature and high alkaline conditions
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Papers (51):
  • Chee-Leong Soong, Kengo Deguchi, Michiki Takeuchi, Syoko Kozono, Nobuyuki Horinouchi, Dayong Si, Makoto Hibi, Sakayu Shimizu, Jun Ogawa. Gene identification and enzymatic characterization of the initial enzyme in pyrimidine oxidative metabolism, uracil-thymine dehydrogenase. Journal of Bioscience and Bioengineering. 2024
  • Taku Mizutani, Ryotaro Hara, Michiki Takeuchi, Makoto Hibi, Makoto Ueda, Jun Ogawa. One-Pot Synthesis of Useful S-Substituted-l-cysteine Sulfoxides Using Genetically Engineered Escherichia coli. Journal of Agricultural and Food Chemistry. 2024. 72. 10. 5339-5347
  • Samantha DM Arras, Nellie SibaevaRyan, J Catchpole, Nobuyuki Horinouchi, Dayong Si, Alannah M Rickerby, Kengo Deguchi, Makoto Hibi, Koichi Tanaka, Michiki Takeuchi, et al. Characterisation of an Escherichia coli line that completely lacks ribonucleotide reduction yields insights into the evolution of parasitism and endosymbiosis. eLife. 2023. e83845
  • Taku Mizutani, Ryotaro Hara, Takayuki Iihoshi, Shoko Kozono, Michiki Takeuchi, Makoto Hibi, Satomi Takahashi, Makoto Ueda, Jun Ogawa. Identification of tryptophanase from Escherichia coli for the synthesis of S-allyl-l-cysteine and related S-substituted cysteine derivatives. Journal of Bioscience and Bioengineering. 2022
  • Taku Mizutani, Ryotaro Hara, Michiki Takeuchi, Kazuo Yamagishi, Yoshinori Hirao, Kenichi Mori, Makoto Hibi, Makoto Ueda, Jun Ogawa. l-Tryptophan-starved cultivation enhances S-allyl-l-cysteine synthesis in various food-related microorganisms. Bioscience, biotechnology, and biochemistry. 2022. 86. 6. 792-799
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MISC (111):
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Patents (10):
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Books (2):
  • Imides
    Elsevier 2019 ISBN:9780128156759
  • Green Biocatalysis
    John Wiley & Sons, Inc. 2016 ISBN:9781118822296
Lectures and oral presentations  (117):
  • Elucidation of α-aminoisobutyric acid hydroxylase, a novel non-heme diiron enzyme from Rhodococcus wratislaviensis
    (2nd Japan-Switzerland-Germany Workshop on Biocatalysis and Bioprocess Development 2021)
  • Characterization of uracil-thymine dehydrogenase in pyrimidine oxidative metabolism of Rhodococcus erythropolis JCM 3132
    (1st Japan-Germany-Switzerland Workshop for Enzyme Technology and Bioprocess Development 2019)
  • Enzymatic process for useful amino acid synthesis using microbial Fe(II)/α-ketoglutarate-dependent dioxygenases
    (1st Japan-Germany-Switzerland Workshop for Enzyme Technology and Bioprocess Development 2019)
  • Tandem enzymatic reactions for the production of a phytochemical L-(+)-alliin
    (1st Japan-Germany-Switzerland Workshop for Enzyme Technology and Bioprocess Development 2019)
  • Production of (+)-alliin by tandem enzymatic reactions
    (The 14th Asian Congress on Biotechnology 2019)
more...
Education (3):
  • 1999 - 2002 Hokkaido University Faculty of Science Department of Biological Sciences
  • 1997 - 1999 Hokkaido University Faculty of Science Department of Biological Sciences
  • 1993 - 1997 Hokkaido University School or Sclence
Professional career (1):
  • 博士(理学) (北海道大学)
Work history (4):
  • 2017/04 - 現在 Toyama Prefectural University Department of Biotechnology Associate Professor
  • 2016/05 - 2017/03 Kyoto University Industrial Microbiology, Graduate School of Agriculture Associate Professor
  • 2006/04 - 2016/05 Kyoto University Industrial Microbiology, Graduate School of Agriculture Assistant Professor
  • 2003/04 - 2006/03 Japan Bioindustry Association Kyowa Hakko Kogyo Postdoctoral Fellow
Committee career (1):
  • 2021/01 - 現在 酵素工学研究会 幹事
Awards (5):
  • 2019/10 - 一般財団法人バイオインダストリー協会 第3回バイオインダストリー奨励賞 新規なアミノ酸変換酵素触媒の同定とその応用利用に関する技術開発
  • 2013/10 - 酵素工学研究会 平成25年度酵素工学奨励賞 新規微生物酸化酵素群の産業利用に向けた基盤技術開発
  • 2013/06 - 天野エンザイム 第14回酵素応用シンポジウム研究奨励賞 不斉変換触媒として有用なアミノ酸酸素原子添加酵素の開発
  • 2013/05 - 新化学技術推進協会 第2回新化学技術研究奨励賞 水酸化反応に有効な新規代謝経路を付与した生体触媒による産業的生産システムの構築
  • 2010/09 - バイオインダストリー協会 2010年度発酵と代謝研究奨励金 微生物酵素を活用する機能性水酸化アミノ酸の生産
Association Membership(s) (3):
JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY ,  The Society for Biotechnology, Japan ,  Japanese Society of Enzyme Engineering
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