文献

J-GLOBAL ID：201602270596320221   整理番号：16A1332283

B型肝炎ウイルスの不活性化のための高度にマルチプレックス化されたCRISPR-Cas9-ヌクレアーゼとCas9-ニッカーゼベクター

Highly multiplexed CRISPR-Cas9-nuclease and Cas9-nickase vectors for inactivation of hepatitis B virus

著者 (8件)： Sakuma Tetsushi (Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima, 739-8526, Japan) ,  Masaki Keiichi (Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan) ,  Abe-Chayama Hiromi (Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan) ,  Abe-Chayama Hiromi (Center for Medical Specialist Graduate Education and Research, Institute of Biomedical & Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan) ,  Mochida Keiji (Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima, 739-8526, Japan) ,  Yamamoto Takashi (Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima, 739-8526, Japan) ,  Chayama Kazuaki (Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan) ,  Chayama Kazuaki (Laboratory for Digestive Diseases, RIKEN Center for Genomic Medicine, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan)
資料名： Genes to Cells  (Genes to Cells)
巻： 21  号： 11  ページ： 1253-1262  発行年： 2016年11月 
JST資料番号： W0935A  ISSN： 1356-9597  CODEN： GECEFL  資料種別： 逐次刊行物 (A)
記事区分： 短報  発行国： オーストラリア (AUS)  言語： 英語 (EN)

抄録/ポイント： CRISPR-Cas9媒介ゲノム編集技術は,基本的なゲノム研...

シソーラス用語： *B型肝炎ウイルス ,...
準シソーラス用語： CRISPR-Casシステム ,...

ログイン（無料）して見る     続きはJDreamIII（有料）にて  {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=16A1332283&from=J-GLOBAL&jstjournalNo=W0935A") }}

分類 (1件)： 遺伝子操作  (EC02050B)

引用文献 (29件)：

• Bloom, K., Ely, A., Mussolino, C., Cathomen, T. & Arbuthnot, P. (2013) Inactivation of hepatitis B virus replication in cultured cells and in vivo with engineered transcription activator-like effector nucleases. Mol. Ther. 21, 1889-1897.
• Cradick, T.J., Keck, K., Bradshaw, S., Jamieson, A.C. & McCaffrey, A.P. (2010) Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs. Mol. Ther. 18, 947-954.
• Cradick, T.J., Qiu, P., Lee, C.M., Fine, E.J. & Bao, G. (2014) COSMID: a web-based tool for identifying and validating CRISPR/Cas off-target sites. Mol. Ther. Nucleic Acids 3, e214.
• Dong, C., Qu, L., Wang, H., Wei, L., Dong, Y. & Xiong, S. (2015) Targeting hepatitis B virus cccDNA by CRISPR/ Cas9 nuclease efficiently inhibits viral replication. Antiviral Res. 118, 110-117.
• Fu, Y., Sander, J.D., Reyon, D., Cascio, V.M. & Joung, J.K. (2014) Improving CRISPR-Cas nuclease specificity using truncated guide RNAs. Nat. Biotechnol. 32, 279-284.

タイトルに関連する用語 (6件)： B型肝炎ウイルス ,  不活性化 ,  マルチプレックス ,  CRISPR-Cas9 ,  ヌクレアーゼ ,  Cas9