文献

J-GLOBAL ID：201202239865104715   整理番号：12A0056116

エゼチミブ単独療法は酸化ストレスを減少させることで高コレステロール血症患者の血管機能を改善する

Ezetimibe Monotherapy Ameliorates Vascular Function in Patients with Hypercholesterolemia Through Decreasing Oxidative Stress

著者 (18件)： KUROBE Hirotsugu (Dep. of Cardiovascular Surgery, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  AIHARA Ken-ichi (Dep. of Medicine and Bioregulatory Sciences, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  HIGASHIDA Mayuko (Dep. of Nutrition & Metabolism, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  HIRATA Yoichiro (Dep. of Cardiovascular Medicine, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  NISHIYA Masako (Div. of Nursing, Tokushima Univ. Hospital.) ,  MATSUOKA Yuki (Dep. of Cardiovascular Surgery, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  KANBARA Tamotsu (Dep. of Cardiovascular Surgery, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  NAKAYAMA Taisuke (Dep. of Cardiovascular Surgery, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  KINOSHITA Hajime (Dep. of Cardiovascular Surgery, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  SUGANO Mikio (Dep. of Cardiovascular Surgery, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  FUJIMOTO Eiki (Dep. of Cardiovascular Surgery, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  KUROBE Ayako (Div. of Nursing, Tokushima Univ. Hospital.) ,  SUGASAWA Noriko (Dep. of Cardiovascular Surgery, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  KITAICHI Takashi (Dep. of Cardiovascular Surgery, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  AKAIKE Masashi (Dep. of Medical Education, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  SATA Masataka (Dep. of Cardiovascular Medicine, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  MATSUMOTO Toshio (Dep. of Medicine and Bioregulatory Sciences, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.) ,  KITAGAWA Tetsuya (Dep. of Cardiovascular Surgery, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School.)
資料名： Journal of Atherosclerosis and Thrombosis (Web)  (Journal of Atherosclerosis and Thrombosis (Web))
巻： 18  号： 12  ページ： 1080-1089 (J-STAGE)  発行年： 2011年 
JST資料番号： U0153A  ISSN： 1880-3873  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 目的:コレステロールの腸管吸収阻害剤であるエゼチミブは脂質低...

シソーラス用語： ヒト ,...
準シソーラス用語： ボディマスインデックス ,...

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分類 (3件)： 循環系疾患の薬物療法  (GJ05020M) ,  脂質代謝作用薬の臨床への応用  (GW13050X) ,  代謝異常・栄養性疾患の治療  (GD05030F)

物質索引 (1件)： エゼチミブ

引用文献 (29件)：

• 1) Miyashita Y, Endo K, Saiki A, Ban N, Yamaguchi T, Kawana H, Nagayama D, Ohira M, Oyama T, Shirai K: Effects of pitavastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, on cardio-ankle vascular index in type 2 diabetic patients. J Atheroscler Thromb, 2009; 16: 539-545
• 2) Executive summary of the third report of the national cholesterol education program (ncep) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel iii). JAMA, 2001; 285: 2486-2497
• 3) Davidson MH, Maki KC, Pearson TA, Pasternak RC, Deedwania PC, McKenney JM, Fonarow GC, Maron DJ, Ansell BJ, Clark LT, Ballantyne CM: Results of the national cholesterol education (ncep) program evaluation project utilizing novel e-technology (neptune) ii survey and implications for treatment under the recent ncep writing group recommendations. Am J Cardiol, 2005; 96: 556-563
• 4) Altmann SW, Davis HR Jr, Zhu LJ, Yao X, Hoos LM, Tetzloff G, Iyer SP, Maguire M, Golovko A, Zeng M, Wang L, Murgolo N, Graziano MP: Niemann-pick c1 like 1 protein is critical for intestinal cholesterol absorption. Science, 2004; 303: 1201-1204
• 5) Garcia-Calvo M, Lisnock J, Bull HG, Hawes BE, Burnett DA, Braun MP, Crona JH, Davis HR Jr, Dean DC, Detmers PA, Graziano MP, Hughes M, Macintyre DE, Ogawa A, O'Neill K A, Iyer SP, Shevell DE, Smith MM, Tang YS, Makarewicz AM, Ujjainwalla F, Altmann SW, Chapman KT, Thornberry NA: The target of ezetimibe is niemann-pick c1-like 1 (npc1l1). Proc Natl Acad Sci U S A, 2005; 102: 8132-8137

タイトルに関連する用語 (6件)： エゼチミブ ,  単独療法 ,  酸化ストレス ,  高コレステロール血症 ,  患者 ,  血管機能