藤原浩樹

Fujiwara Hiroki

研究分野 (1件)：神経科学一般

論文 (23件)：

Homma Takujiro, Fujiwara Hiroki, Osaki Tsukasa, Fujii Satoshi, Fujii Junichi. Consequences of a peroxiredoxin 4 (Prdx4) deficiency on learning and memory in mice. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2022. 621. 32-38
Goto Jun-Ichi, Fujii Satoshi, Fujiwara Hiroki, Mikoshiba Katsuhiko, Yamazaki Yoshihiko. Synaptic plasticity in hippocampal CA1 neurons of mice lacking inositol-1,4,5-trisphosphate receptor-binding protein released with IP3 (IRBIT). LEARNING & MEMORY. 2022. 29. 4. 110-119
Sugiura Hiroko, Shimada Tadayuki, Moriya-Ito Keiko, Goto Jun-Ichi, Fujiwara Hiroki, Ishii Rie, Shitara Hiroshi, Taya Choji, Fujii Satoshi, Kobayashi Toshiyuki, et al. A Farnesyltransferase Inhibitor Restores Cognitive Deficits in Tsc2(+/-) Mice through Inhibition of Rheb1. JOURNAL OF NEUROSCIENCE. 2022. 42. 12. 2598-2612
Fujii S, Yamazaki Y, Goto JI, Fujiwara H, Mikoshiba K. Depotentiation depends on IP3 receptor activation sustained by synaptic inputs after LTP induction. Learning & Memory. 2020. 27. 2. 52-66
Kurihara K, Homma T, Kobayashi S, Shichiri M, Fujiwara H, Fujii S, Yamada KI, Nakane M, Kawamae K, Fujii J. Ascorbic acid insufficiency impairs spatial memory formation in juvenile AKR1A-knockout mice. ournal of Clinical Biochemistry and Nutrition. 2019. 65. 3. 209-216

講演・口頭発表等 (11件)：

DGK-εKOマウスを用いた行動実験
(山形医学)
IP3 receptor binding protein released with IP3(IRBIT)欠損マウスにおける高次脳機能への影響
(日本生理学雑誌)
持続的なシナプス入力はNMDA受容体および代謝型グルタミン酸受容体-IP3受容体活性化の下流のタンパク質リン酸化/脱リン酸化を介して脱増強とLTP抑制を制御する(Sustained synaptic input regulates depotentiation and LTP suppression via the protein phosphorylation / dephosphorylation under the activation of NMDAR and mGluR-IP3R)
(The Journal of Physiological Sciences)
IP3 receptor binding protein released with IP3(IRBIT)欠損マウスを用いた学習行動解析
(山形医学)
IP3 receptor binding protein released with IP3(IRBIT)KOマウスを用いた学習行動実験
(山形医学)

経歴 (1件)：

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藤原 浩樹