文献

J-GLOBAL ID：201902291512567158   整理番号：19A2931580

アスコルビン酸欠乏は幼若AKR1Aノックアウトマウスにおける空間記憶形成を損なう

Ascorbic acid insufficiency impairs spatial memory formation in juvenile AKR1A-knockout mice

著者 (12件)： Kurihara Kazuki (Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University) ,  Kurihara Kazuki (Department of Anesthesiology, Faculty of Medicine, Yamagata University) ,  Homma Takujiro (Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University) ,  Kobayashi Sho (Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University) ,  Shichiri Mototada (Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)) ,  Fujiwara Hiroki (Department of Physiology, Faculty of Medicine, Yamagata University) ,  Fujii Satoshi (Department of Physiology, Faculty of Medicine, Yamagata University) ,  Yamada Ken-ichi (Physical Chemistry for Life Science Laboratory, Faculty of Pharmaceutical Sciences, Kyushu University) ,  Yamada Ken-ichi (AMED-CREST, Japan Agency for Medical Research and Development) ,  Nakane Masaki (Department of Emergency and Critical Care Medicine, Faculty of Medicine, Yamagata University) ,  Kawamae Kaneyuki (Department of Anesthesiology, Faculty of Medicine, Yamagata University) ,  Fujii Junichi (Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University)
資料名： Journal of Clinical Biochemistry and Nutrition  (Journal of Clinical Biochemistry and Nutrition)
巻： 65  号： 3  ページ： 209-216(J-STAGE)  発行年： 2019年 
JST資料番号： X0851A  ISSN： 0912-0009  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： アルド-ケトレダクターゼのAKR1Aは,アスコルビン酸の合成...

シソーラス用語： ノックアウトマウス ,...
準シソーラス用語： AKR1A遺伝子 ,...

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著者キーワード (4件)： アスコルビン酸 ,  AKR1A ,  Morris水迷路 ,  空間記憶

分類 (2件)： 神経の基礎医学  (GN01020W) ,  ビタミンC  (EB07040W)

物質索引 (1件)： アスコルビン酸

引用文献 (44件)：

• 1 Mandl J, Szarka A, Bánhegyi G. Vitamin C: update on physiology and pharmacology. Br J Pharmacol 2009; 157: 1097-1110.
• 2 Hess CR, McGuirl MM, Klinman JP. Mechanism of the insect enzyme, tyramine beta-monooxygenase, reveals differences from the mammalian enzyme, dopamine beta-monooxygenase. J Biol Chem 2008; 283: 3042-3049.
• 3 Castro MA, Beltrán FA, Brauchi S, Concha II. A metabolic switch in brain: glucose and lactate metabolism modulation by ascorbic acid. J Neurochem 2009; 110: 423-440.
• 4 Ballaz S, Morales I, Rodríguez M, Obeso JA. Ascorbate prevents cell death from prolonged exposure to glutamate in an in vitro model of human dopaminergic neurons. J Neurosci Res 2013; 91: 1609-1617.
• 5 Guo YE, Suo N, Cui X, Yuan Q, Xie X. Vitamin C promotes oligodendrocytes generation and remyelination. Glia 2018; 66: 1302-1316.

タイトルに関連する用語 (3件)： アスコルビン酸欠乏 ,  ノックアウトマウス ,  記憶形成