研究者
J-GLOBAL ID:200901095723829231   更新日: 2020年06月04日

森 隆

Mori Takashi
所属機関・部署:
職名: 教授
競争的資金等の研究課題 (6件):
  • 2014 - 2018 アルツハイマー病:食物由来のβーアミロイド蛋白抑制物質の併用療法と環境療法の探索
  • 2010 - 2014 アルツハイマー病治療の開発:食物由来のβーアミロイド蛋白抑制物質と環境療法の探索
  • 2007 - 2011 Alzheimer病:脳 βアミロイド沈着防止方法の神経病理学的検討
  • 2006 - 2010 アルツハイマー病の病態進展過程におけるグリア細胞の役割
  • 2005 - 2008 細胞死抑制活性強化蛋白質の細胞内導入治療法による肝組織変性の抑制
全件表示
論文 (29件):
  • Darrell Sawmiller, Ahsan Habib, Huayan Hou, Takashi Mori, Anran Fan, Jun Tian, Jin Zeng, Brian Giunta, Paul R. Sanberg, Mark P. Mattson, Jun Tan. A novel apolipoprotein E antagonist functionally blocks apolipoprotein E interaction with N-terminal amyloid precurcor protein, reduces β-amyloid-associated pathology, and improves cognition. Biological Psychiatry. 2019. ***-***
  • Takashi Mori, Naoki Koyama, Jun Tan, Tatsuya Segawa, Masahiro Maeda, Terrence Town. Combined treatment with the phenolics (-)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice. Journal of biological Chemystry. 2019. 294. 8. 2714-2731
  • Ahsan Habib, Huayan Hou, Takashi Mori, Jun Tian, Jin Zeng, Shengnuo Fan, Brian Giunta, Paul R. Sanberg, Darrell Sawmiller, Jun Tan. Human umbilical cord blood serum-derived α-secretase: Functional testing in Alzheimer's disease mouse models. Cell Transplant. 2018
  • Ahsan Habib, Darrell Sawmiller, Song Li, Yang Xiang, David Rongo, Jun Tian, Huayan Hou, Jin Zeng, Adam Smith, Shengnuo Arnord Fan, Brian Giunta, Takashi Mori, Glenn Currier, R. Douglas Shytle, Jun Tan. LISPRO mitigates β-amyloid and associated pathologies in Alzheimer's mice. Cell Death Dis. 2017. e2880
  • Takashi Mori, Naoki Koyama, Jun Tan, Tatsuya Segawa, Masahiro Maeda, Terrence Town. Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer disease. J Biol Chem. 2017. 92. 27. 11310-11325
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講演・口頭発表等 (34件):
  • Immune checkpoint inhibition induce activated dendritic cell infration in PD-L1 negative tumor in mouse neuroblastoma model.
    (50th Congress of the Internatinal Society of Paediatric Oncology 2018)
  • Combination therapy with (-)-epigallocatechin-3-gallate and ferulic acid effectively modifies Alzheimer-like pathology.
    (Neuroscience 17 2017)
  • LISPRO, an ionic cocrystal of lithium, mitigates Alzheimer-like pathological changes in the mice.
    (Neuroscience 17 2017)
  • LISPRO, an ionic cocrystal of lithium, mitigates Alzheimer-like pathological changes in the mice.
    (24th Annual Meeting of the American Society for Neural Therapy and Repair 2017)
  • Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
    (Neuroscience 15 2015)
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学位 (1件):
  • 博士(獣医学) (日本獣医生命科学大学)
委員歴 (1件):
  • 1996/04 - 現在 日本脳循環代謝学会 評議員
所属学会 (6件):
Member of the Society for Neuroscience (Washington, U.S.A.) ,  日本認知症学会 ,  日本脳循環代謝学会 ,  日本獣医病理学専門家協会 ,  日本獣医病理学会 ,  日本獣医学会
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