伊藤拓水

イトウタクミ | Ito Takumi

研究分野 (1件)：生物分子化学

研究キーワード (6件)：ユビキチンリガーゼ , セレブロン , 多発性骨髄腫 , IMiDs , サリドマイド , ケミカルバイオロジー

競争的資金等の研究課題 (8件)：

全件表示

論文 (50件)：

Kiwamu Hatakeyama, Yoshikane Kikushige, Daisuke Ishihara, Shunsuke Yamamoto, Gentaro Kawano, Taro Tochigi, Toshihiro Miyamoto, Teppei Sakoda, Andy Christoforou, Yuya Kunisaki, et al. Thrombospondin-1 is an endogenous substrate of cereblon responsible for immunomodulatory drugs-induced thromboembolism. Blood advances. 2024
Takumi Ito. Protein degraders -from thalidomide to new PROTACs. The Journal of Biochemistry. 2023
Takumi Ito, Tomoko Asatsuma-Okumura, Akinori Endo, Junichi Yamamoto, Yoshiko Iwai, Yuki Yamaguchi, Mikihiko Naito, Hiroshi Handa, Yasushi Saeki. ZNF276 and WIZ are CRBN neosubstrates involved in the anti-angiogenic activity of thalidomide and immunomodulatory drugs. 2023
Akihiro Kimura, Takeshi Takagi, Thiprampai Thamamongood, Satoshi Sakamoto, Takumi Ito, Iwao Seki, Masahiro Okamoto, Hiroyuki Aono, Satoshi Serada, Tetsuji Naka, et al. Extracellular aaRSs drive autoimmune and inflammatory responses in rheumatoid arthritis via the release of cytokines and PAD4. Annals of the rheumatic diseases. 2023
Junichi Yamamoto, Tomoko Asatsuma-Okumura, Takumi Ito, Yuki Yamaguchi, Hiroshi Handa. History of IMiDs and protein degradation as a pharmacological modality. Protein Homeostasis in Drug Discovery: A Chemical Biology Perspective. 2022. 285-315

MISC (43件)：

特許 (13件)：

学歴 (2件)：

経歴 (4件)：

受賞 (2件)：

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伊藤 拓水