文献

J-GLOBAL ID：201202276761315431   整理番号：12A0394448

ビタミンC欠乏老化指標蛋白質-30/グルコノラクトナーゼノックアウトマウスにおける膵臓インスリン放出

Pancreatic insulin release in vitamin C-deficient senescence marker protein-30/gluconolactonase knockout mice

著者 (11件)： SENMARU Takafumi (Dep. of Endocrinology and Metabolism, Kyoto Prefectural Univ. of Medicine Graduate School of Medical Sci.) ,  YAMAZAKI Masahiro (Dep. of Endocrinology and Metabolism, Kyoto Prefectural Univ. of Medicine Graduate School of Medical Sci.) ,  OKADA Hiroshi (Dep. of Endocrinology and Metabolism, Kyoto Prefectural Univ. of Medicine Graduate School of Medical Sci.) ,  ASANO Mai (Dep. of Endocrinology and Metabolism, Kyoto Prefectural Univ. of Medicine Graduate School of Medical Sci.) ,  FUKUI Michiaki (Dep. of Endocrinology and Metabolism, Kyoto Prefectural Univ. of Medicine Graduate School of Medical Sci.) ,  NAKAMURA Naoto (Dep. of Endocrinology and Metabolism, Kyoto Prefectural Univ. of Medicine Graduate School of Medical Sci.) ,  OBAYASHI Hiroshi (Inst. of Bio-Response Informatics) ,  KONDO Yoshitaka (Aging Regulation, Tokyo Metropolitan Inst. of Gerontology) ,  MARUYAMA Naoki (Aging Regulation, Tokyo Metropolitan Inst. of Gerontology) ,  ISHIGAMI Akihito (Aging Regulation, Tokyo Metropolitan Inst. of Gerontology) ,  HASEGAWA Goji (Dep. of Endocrinology and Metabolism, Kyoto Prefectural Univ. of Medicine Graduate School of Medical Sci.)
資料名： Journal of Clinical Biochemistry and Nutrition  (Journal of Clinical Biochemistry and Nutrition)
巻： 50  号： 2  ページ： 114-118 (J-STAGE)  発行年： 2012年 
JST資料番号： X0851A  ISSN： 0912-0009  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 我々は,最近,老化指標蛋白質-30が,ラクトンを加水分解する...

シソーラス用語： ノックアウトマウス ,...
準シソーラス用語： *インシュリン ,...

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分類 (1件)： ビタミンC  (EB07040W)

物質索引 (1件)： ビタミンC

引用文献 (31件)：

• 1 Fujita T, Uchida K, Maruyama N. Purification of senescence marker protein-30 (SMP30) and its androgen-independent decrease with age in the rat liver. Biochim Biophys Acta 1992; 1116: 122–128.
• 2 Ishigami A, Maruyama N. Significance of SMP30 in gerontology. Geriatr Gerontol Int 2007; 7: 316–325.
• 3 Kondo Y, Inai Y, Sato Y, et al. Senescence marker protein 30 functions as gluconolactonase in L-ascorbic acid biosynthesis, and its knockout mice are prone to scurvy. Proc Natl Acad Sci USA 2006; 103: 5723–5728.
• 4 Ishigami A, Fujita T, Handa S, et al. Senescence marker protein-30 knockout mouse liver is highly susceptible to tumor necrosis factor-alpha- and Fas-mediated apoptosis. Am J Pathol 2002; 161: 1273–1281.
• 5 Ishigami A, Kondo Y, Nanba R, et al. SMP30 deficiency in mice causes an accumulation of neutral lipids and phospholipids in the liver and shortens the life span. Biochem Biophys Res Commun 2004; 315: 575–580.

タイトルに関連する用語 (4件)： ビタミンC欠乏 ,  老化指標蛋白質-30 ,  膵臓 ,  インスリン放出