文献

J-GLOBAL ID：201402287260843442   整理番号：14A0044190

大豆由来のイソフラボンは,SIRT1の活性化を通じてC2C12筋管におけるMuRF1を介した筋萎縮を防止する

Isoflavones Derived from Soy Beans Prevent MuRF1-Mediated Muscle Atrophy in C2C12 Myotubes through SIRT1 Activation

著者 (14件)： HIRASAKA Katsuya (Dep. of Nutritional Physiology, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  MAEDA Tasuku (Dep. of Nutritional Physiology, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  IKEDA Chika (Dep. of Nutritional Physiology, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  HARUNA Marie (Dep. of Nutritional Physiology, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  KOHNO Shohei (Dep. of Nutritional Physiology, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  ABE Tomoki (Dep. of Nutritional Physiology, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  OCHI Arisa (Dep. of Nutritional Physiology, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  MUKAI Rie (Dep. of Food Sci., Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  OARADA Motoko (Medical Mycology Res. Center, Chiba Univ.) ,  ESHIMA-KONDO Shigetada (Dep. of Nutritional Physiology, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  OHNO Ayako (Dep. of Nutritional Physiology, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  OKUMURA Yuushi (Dep. of Nutritional Physiology, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  TERAO Junji (Dep. of Food Sci., Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  NIKAWA Takeshi (Dep. of Nutritional Physiology, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School)
資料名： Journal of Nutritional Science and Vitaminology  (Journal of Nutritional Science and Vitaminology)
巻： 59  号： 4  ページ： 317-324 (J-STAGE)  発行年： 2013年 
JST資料番号： F0733A  ISSN： 0301-4800  CODEN： JNSVA5  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 炎症性サイトカインは,筋萎縮を引き起こして,骨格筋のユビキチ...

シソーラス用語： *イソフラボノイド ,...
準シソーラス用語： *MuRF1 ,...

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分類 (3件)： 食品の化学・栄養価  (FJ01020J) ,  運動器系の基礎医学  (GG01020B) ,  筋肉  (EJ10020G)

物質索引 (2件)： ゲニステイン【フラボノイド】 ,  ダイゼイン

引用文献 (30件)：

• 1) Ikemoto M, Nikawa T, Takeda S, Watanabe C, Kitano T, Baldwin KM, Izumi R, Nonaka I, Towatari T, Teshima S, Rokutan K, Kishi K. 2001. Space shuttle flight (STS-90) enhances degradation of rat myosin heavy chain in association with activation of ubiquitin-proteasome pathway. FASEB J 15: 1279-1281.
• 2) Ogawa T, Furochi H, Mameoka M, Hirasaka K, Onishi Y, Suzue N, Oarada M, Akamatsu M, Akima H, Fukunaga T, Kishi K, Yasui N, Ishidoh K, Fukuoka H, Nikawa T. 2006. Ubiquitin ligase gene expression in healthy volunteers with 20-day bedrest. Muscle Nerve 34: 463-469.
• 3) Bodine SC, Latres E, Baumhueter S, Lai VK, Nunez L, Clarke BA, Poueymirou WT, Panaro FJ, Na E, Dharmarajan K, Pan ZQ, Valenzuela DM, DeChiara TM, Stitt TN, Yancopoulos GD, Glass DJ. 2001. Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294: 1704-1708.
• 4) Gomes MD, Lecker SH, Jagoe RT, Navon A, Goldberg AL. 2001. Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy. Proc Natl Acad Sci USA 98: 14440-14445.
• 5) Tintignac LA, Lagirand J, Batonnet S, Sirri V, Leibovitch MP, Leibovitch SA. 2005. Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase. J Biol Chem 280: 2847-2856.

タイトルに関連する用語 (7件)： 大豆 ,  イソフラボン ,  SIRT1 ,  活性化 ,  筋管 ,  MuRF1 ,  筋萎縮