文献

J-GLOBAL ID：201502201060487273   整理番号：15A1328789

エンドセリン受容体アンタゴニスト ボセンタンの軽度症候性肺動脈高血圧症の日本人患者における循環動態および運動能力への効果

Effects of the endothelin receptor antagonist bosentan on hemodynamics and exercise capacity in Japanese patients with mildly symptomatic pulmonary arterial hypertension

著者 (12件)： HATANO Masaru (The Univ. of Tokyo, Dep. of Cardiovascular Medicine, Graduate School of Medicine, 7-3-1 Hongo, 113-8655, Bunkyo-ku ...) ,  YAMADA Hidehiro (St. Marianna Univ. School of Medicine, Div. of Rheumatology and Allergy, Dep. of Internal Medicine, Kanagawa, JPN) ,  FUKUDA Keiichi (Keio Univ. School of Medicine, Dep. of Cardiology, Tokyo, JPN) ,  YOSHIOKA Koichiro (Tokai Univ. School of Medicine, Dep. of Cardiovascular Medicine, Kanagawa, JPN) ,  FUNAUCHI Masanori (Kinki Univ. Fac. of Medicine, Dep. of Hematology and Rheumatology, Osaka, JPN) ,  KUWANA Masataka (Keio Univ. School of Medicine, Div. of Rheumatology, Dep. of Internal Medicine, Tokyo, JPN) ,  SATA Masataka (The Univ. of Tokushima Graduate School, Dep. of Cardiovascular Medicine, Inst. of Health Biosciences, Tokushima, JPN) ,  TANIGUCHI Mitsugu (Kinki Univ. Fac. of Medicine, Div. of Cardiology, Osaka, JPN) ,  NAKANISHI Norifumi (National Cerebral and Cardiovascular Center, Div. of Pulmonary Circulation, Dep. of Cardiovascular Medicine, Osaka, JPN) ,  SAITO Takefumi (National Hospital Organization Ibaraki-Higashi National Hospital, Dep. of Respiratory Medicine, Ibaraki, JPN) ,  SAJI Tsutomu (Toho Univ. Omori Medical Center, Dep. of Pediatrics, Tokyo, JPN) ,  SASAYAMA Shigetake (Kyoto Univ., Kyoto, JPN)
資料名： Heart and Vessels  (Heart and Vessels)
巻： 30  号： 6  ページ： 798-804  発行年： 2015年11月 
JST資料番号： X0101A  ISSN： 0910-8327  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： ドイツ (DEU)  言語： 英語 (EN)

抄録/ポイント： 肺動脈高血圧症(PAH)の臨床試験はほとんどの場合世界保健機...

シソーラス用語： *肺高血圧症 ,...
準シソーラス用語： WHO分類 ,...

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分類 (2件)： 血管作用薬・降圧薬の臨床への応用  (GW07050U) ,  循環系疾患の薬物療法  (GJ05020M)

物質索引 (1件)： ボセンタン

引用文献 (20件)：

• D’Alonzo GE, Barst RJ, Ayres SM, Bergofsky EH, Brundage BH, Detre KM, Fishman AP, Goldring RM, Groves BM, Kernis JT, Levy PS, Pietra GG, Reid LM, Reeves JT, Rich S, Vreim CE, Williams GW, Wu M (1991) Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann Intern Med 115:343-349
• Galiè N, Lj Rubin, Hoeper M, Jansa P, Al-Hiti H, Meyer G, Chiossi E, Kusic-Pajic A, Simonneau G (2008) Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial. Lancet 371:2093-2100
• Sasayama S, Yoshida K, Okazaki A, Nishimoto S (2012) Results of Japanese post-marketing surveillance of bosentan in pulmonary hypertension (in Japanese). Pharma Medica 30:141-156
• Humbert M, Sitbon O, Chaouat A, Bertocchi M, Habib G, Gressin V, Yaïci A, Weitzenblum E, Cordier JF, Chabot F, Dromer C, Pison C, Reynaud-Gaubert M, Haloun A, Laurent M, Hachulla E, Cottin V, Degano B, Jaïs X, Montani D, Souza R, Simonneau G (2010) Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era. Circulation 122:156-163
• Benza RL, Gomberg-Maitland M, Naeije R, Arneson CP, Lang IM (2011) Prognostic factors associated with increased survival in patients with pulmonary arterial hypertension treated with subcutaneous treprostinil in randomized, placebo-controlled trials. J Heart Lung Transplant 30:982-989

タイトルに関連する用語 (9件)： エンドセリン受容体アンタゴニスト ,  ボセンタン ,  軽度 ,  症候 ,  肺動脈高血圧症 ,  日本人 ,  患者 ,  循環動態 ,  運動能力