文献

J-GLOBAL ID：201502240302716242   整理番号：15A0678146

長期間の高脂肪食はマウス体内の鉄分布を変化させ,特に,脾臓における鉄蓄積を増加させる

A Long-Term High-Fat Diet Changes Iron Distribution in the Body, Increasing Iron Accumulation Specifically in the Mouse Spleen

著者 (10件)： YAMANO Noriko (Dep. of Pharmacology, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School) ,  IKEDA Yasumasa (Dep. of Pharmacology, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School) ,  SAKAMA Minoru (Dep. of Radiological Sci., Inst. of Health Biosciences, The Univ. of Tokushima Graduate School) ,  IZAWA-ISHIZAWA Yuki (Dep. of Pharmacology, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School) ,  KIHIRA Yoshitaka (Dep. of Pharmacology, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School) ,  ISHIZAWA Keisuke (Dep. of Medical Pharmacology, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School) ,  MIYAMOTO Licht (Dep. of Medical Pharmacology, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School) ,  TOMITA Shuhei (Div. of Molecular Pharmacology, Fac. of Medicine, Tottori Univ.) ,  TSUCHIYA Koichiro (Dep. of Medical Pharmacology, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School) ,  TAMAKI Toshiaki (Dep. of Pharmacology, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School)
資料名： Journal of Nutritional Science and Vitaminology  (Journal of Nutritional Science and Vitaminology)
巻： 61  号： 1  ページ： 20-27 (J-STAGE)  発行年： 2015年 
JST資料番号： F0733A  ISSN： 0301-4800  CODEN： JNSVA5  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 鉄は必須微量金属であるが,その過剰な存在は人体に酸化ストレス...

シソーラス用語： *高脂肪食 ,...
準シソーラス用語： DMT1 ,...

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分類 (2件)： 代謝異常・栄養性疾患一般  (GD05010J) ,  動物の代謝と栄養一般  (EJ02031R)

引用文献 (23件)：

• 1) Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J. 2004. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306: 2090-2093.
• 2) Fleming RE, Migas MC, Zhou X, Jiang J, Britton RS, Brunt EM, Tomatsu S, Waheed A, Bacon BR, Sly WS. 1999. Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1. Proc Natl Acad Sci USA 96: 3143-3148.
• 3) Mastrogiannaki M, Matak P, Keith B, Simon MC, Vaulont S, Peyssonnaux C. 2009. HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice. J Clin Invest 119: 1159-1166.
• 4) Kremastinos DT, Farmakis D. 2011. Iron overload cardiomyopathy in clinical practice. Circulation 124: 2253-2263.
• 5) Castellani RJ, Moreira PI, Perry G, Zhu X. 2012. The role of iron as a mediator of oxidative stress in Alzheimer disease. Biofactors 38: 133-138.

タイトルに関連する用語 (6件)： 高脂肪食 ,  マウス ,  鉄 ,  分布 ,  脾臓 ,  鉄蓄積