文献

J-GLOBAL ID：201602280777218275   整理番号：16A1315652

IL-27/Stat3軸はリンパ腫の浸潤マクロファージにおけるプログラム細胞死1リガンド(PD-L1/2)の発現を誘導する

An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphoma

著者 (13件)： Horlad Hasita (Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Ma Chaoya (Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Yano Hiromu (Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Pan Cheng (Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Ohnishi Koji (Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Fujiwara Yukio (Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Endo Shinya (Department of Hematology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Kikukawa Yoshitaka (Department of Hematology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Okuno Yutaka (Department of Hematology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Matsuoka Masao (Department of Hematology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Matsuoka Masao (Laboratory of Virus Control, Institute for Virus Research, Kyoto University, Kyoto, Japan) ,  Takeya Motohiro (Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Komohara Yoshihiro (Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan)
資料名： Cancer Science (Web)  (Cancer Science (Web))
巻： 107  号： 11  ページ： 1696-1704  発行年： 2016年 
JST資料番号： U0505A  ISSN： 1349-7006  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： 腫瘍微小環境における免疫逃避および免疫寛容は腫瘍進行と密接に...

シソーラス用語： *インターロイキン ,...
準シソーラス用語： *IL-27 ,...

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著者キーワード (5件)： CD163 ,  macrophage ,  PD-L1 ,  PD-L2 ,  tumor-associated macrophages

分類 (2件)： 血液の腫よう  (GK04000M) ,  基礎腫よう学一般  (GE02010R)

引用文献 (33件)：

• Bingle L, Brown NJ, Lewis CE. The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol 2002; 196: 254-65.
• Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004; 4: 71-8.
• Sica A, Schioppa T, Mantovani A, Allavena P. Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer 2006; 42: 717-27.
• Komohara Y, Jinushi M, Takeya M. Clinical significance of macrophage heterogeneity in human malignant tumors. Cancer Sci 2014; 105: 1-8.
• Komohara Y, Niino D, Ohnishi K, Ohshima K, Takeya M. Role of tumorassociated macrophages in hematological malignancies. Pathol Int 2015; 65: 170-6.

タイトルに関連する用語 (10件)： IL-27 ,  STAT3 ,  リンパ腫 ,  浸潤 ,  マクロファージ ,  プログラム細胞死 ,  リガンド ,  PD-L1 ,  発現 ,  誘導