神沼修

カミヌマオサム | Osamu Kminuma

所属機関・部署：
職名：教授

研究分野 (4件)：分子生物学 , 薬理学 , 免疫学 , 実験動物学

競争的資金等の研究課題 (16件)：

2020 - 2023 歯周病の病態メカニズムに基づく先進的免疫療法の基盤研究
2019 - 2023 免疫研究バイオリソースとしてのT細胞クローンマウスの有用性
2019 - 2022 舌下免疫療法によるマスト細胞脱顆粒抑制機構
2018 - 2021 アレルギー疾患におけるT細胞サブセットに共通する過敏性亢進発症機構の解明
2018 - 2021 ステロイド抵抗性気道炎症の分子基盤解明と新規治療

全件表示

論文 (72件)：

Mamiko Morinaga, Haruyo Nakajima-Adachi, Erika Hiraide, Noriko Kitamura, Osamu Kaminuma, Takachika Hiroi, Katsuyo Ohashi-Doi, Satoshi Hachimura. Epicutaneous allergen administration without antigen delivery device induces local T cell response and alleviates food allergic enteropathy. Allergology international : official journal of the Japanese Society of Allergology. 2020. 69. 4. 622-625
Tomoe Nishimura, Osamu Kaminuma, Mayumi Saeki, Noriko Kitamura, Akio Mori, Takachika Hiroi. Suppressive effect of environmental tobacco smoke on murine Th2 cell-mediated nasal eosinophilic inflammation. Asia Pacific allergy. 2020. 10. 2. e18
Minoru Gotoh, Osamu Kaminuma, Akihiro Nakaya, Mayumi Saeki, Tomoe Nishimura, Noriko Kitamura, Takachika Hiroi, Kimihiro Okubo. Association of Basophil-Expressing Genes with Effectiveness of Sublingual Immunotherapy. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. 2020. 87. 1. 49-52
Masashi Tachibana, Nobumasa Watanabe, Yuzo Koda, Yukako Oya, Osamu Kaminuma, Kazufumi Katayama, Zifei Fan, Fuminori Sakurai, Kenji Kawabata, Takachika Hiroi, et al. Ablation of IL-17A leads to severe colitis in IL-10-deficient mice: implications of myeloid-derived suppressor cells and NO production. International immunology. 2020. 32. 3. 187-201
Noriko Kitamura, Mayumi Shindo, Jun Ohtsuka, Akira Nakamura, Masaru Tanokura, Takachika Hiroi, Osamu Kaminuma. Identification of novel interacting regions involving calcineurin and nuclear factor of activated T cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020. 34. 2. 3197-3208

MISC (25件)：

Kohei Kobatake, Ken-Ichiro Ikeda, Yuichiro Nakata, Norimasa Yamasaki, Takeshi Ueda, Akinori Kanai, Kazuhiro Sentani, Yasuyuki Sera, Tetsutaro Hayashi, Miho Koizumi, et al. Kdm6a Deficiency Activates Inflammatory Pathways, Promotes M2 Macrophage Polarization, and Causes Bladder Cancer in Cooperation with p53 Dysfunction. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020. 26. 8. 2065-2079
Mayumi Saeki, Osamu Kaminuma, Tomoe Nishimura, Noriko Kitamura, Akio Mori, Takachika Hiroi. Th2 and Th9 cells induce airway eosinophilic inflammation by distinct mechanisms. CYTOKINE. 2017. 100. 135-135
Tomoe Nishimura, Osamu Kaminuma, Mayumi Saeki, Noriko Kitamura, Akio Mori, Takachika Hiroi. Influence of environmental tobacco smoke on murine models of allergic nasal inflammation. CYTOKINE. 2017. 100. 136-136
Akio Mori, Satoshi Kouyama, Miyako Yamaguchi, Akemi Ohtomo-Abe, Yosuke Kamide, Hiroaki Hayashi, Kentaro Watai, Chihiro Mitsui, Kiyoshi Sekiya, Takahiro Tsuburai, et al. Blockade of Costimulatory Signal Enhanced Glucocorticoid Suppression of T Cell-Induced Eosinophilia. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017. 139. 2. AB94-AB94
Akio Mari, Satoshi Kouyama, Miyako Yamaguchi, Arisa Kinoshita, Yosuke Kamide, Hiroaki Hayashi, Kentaro Watai, Chihiro Mitsui, Chiyako Oshikata, Kiyoshi Sekiya, et al. Blocking CD28 signal in steroid resistant asthma. JOURNAL OF IMMUNOLOGY. 2016. 196

講演・口頭発表等 (12件)：

Silencing of the NFATc4 gene is crucial for cytokine production by T cells
(第47回日本免疫学会総会 2018)
Functional diversity of NFAT family transcription factors
(第91回日本生化学会大会 2018)
Pharmacological characterization of T cell-induced broncho-constriction in vitro and in vivo.
(ERS International Congress 2018 2018)
Algorithmic prediction of responder and non-responder allergic rhinitis patients recieving sublingual immunotherapy
(18th World Congress of Basic and Clinical Pharmacology 2018)
T細胞の核移植によるアレルギー疾患モデルマウス
(第55回筑波実験動物研究会講演会 2018)

※　J-GLOBALの研究者情報は、researchmapの登録情報に基づき表示しています。登録・更新については、こちらをご覧ください。

前のページに戻る

神沼 修

神沼修