文献

J-GLOBAL ID：201702213827273314   整理番号：17A0431056

C型肝炎ウイルスの未成熟コア蛋白質は酵母モデル系においてERAD-Lの阻害を介して非折畳み蛋白質応答を誘導する

Immature Core protein of hepatitis C virus induces an unfolded protein response through inhibition of ERAD-L in a yeast model system

著者 (14件)： Takahashi Shota (Department of Microbiology, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981-8558, Japan) ,  Sato Naoko (Department of Microbiology, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981-8558, Japan) ,  Sato Naoko (Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan) ,  Kikuchi Junichi (Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan) ,  Kakinuma Hideaki (Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan) ,  Okawa Jun (Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan) ,  Masuyama Yukiko (Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan) ,  Iwasa Singo (Department of Microbiology, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981-8558, Japan) ,  Irokawa Hayato (Department of Microbiology, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981-8558, Japan) ,  Hwang Gi-Wook (Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan) ,  Naganuma Akira (Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan) ,  Kohara Michinori (Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan) ,  Kuge Shusuke (Department of Microbiology, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981-8558, Japan) ,  Kuge Shusuke (Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, 980-8578, Japan)
資料名： Genes to Cells  (Genes to Cells)
巻： 22  号： 2  ページ： 160-173  発行年： 2017年02月 
JST資料番号： W0935A  ISSN： 1356-9597  CODEN： GECEFL  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オーストラリア (AUS)  言語： 英語 (EN)

抄録/ポイント： C型肝炎ウイルス(HCV)の構造蛋白質コア,細胞質蛋白質は肝...

シソーラス用語： *C型肝炎ウイルス ,...
準シソーラス用語： *細胞生理 ,...

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分類 (2件)： ウイルスの生化学  (EG04030F) ,  細胞生理一般  (EF02010S)

引用文献 (57件)：

• Afzal, M.S., Alsaleh, K., Farhat, R., Belouzard, S., Danneels, A., Descamps, V., Duverlie, G., Wychowski, C., Zaidi, N., Dubuisson, J. & Rouille, Y. (2015) Regulation of core expression during the hepatitis C virus life cycle. J. Gen. Virol. 96, 311-321.
• Aizawa, S., Okamoto, T., Sugiyama, Y. et al. (2016) TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis. Nat. Commun. 7, 11379.
• Asselah, T., Bieche, I., Mansouri, A. et al. (2010) In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C. J. Pathol. 221, 264-274.
• Bartenschlager, R., Frese, M. & Pietschmann, T. (2004) Novel insights into hepatitis C virus replication and persistence. Adv. Virus Res. 63, 71-180.
• Bordallo, J., Plemper, R.K., Finger, A. & Wolf, D.H. (1998) Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins. Mol. Biol. Cell 9, 209-222.

タイトルに関連する用語 (9件)： C型肝炎ウイルス ,  成熟 ,  コア蛋白質 ,  酵母 ,  モデル ,  ERAD ,  阻害 ,  非折畳み蛋白質応答 ,  誘導