文献

J-GLOBAL ID：201702216320609775   整理番号：17A0136618

原因不明の女性不妊症におけるJUNO遺伝子の変異分析

Mutation analysis of the JUNO gene in female infertility of unknown etiology

著者 (11件)： Takaiso Nobue (Division of Genetic Counseling, Department of Clinical Laboratory Medicine, Graduate School of Health Sciences, Fujita Health University) ,  Takaiso Nobue (Department of Breast Oncology Aichi Cancer Center Hospital) ,  Nishizawa Haruki (Department of Obstetrics and Gynecology, Fujita Health University School of Medicine) ,  Nishiyama Sachie (Nishiyama Clinic) ,  Sawada Tomio (Sawada Women’s Clinic) ,  Hosoba Eriko (Division of Molecular Genetics, Institute for Comprehensive Medical Sciences, Fujita Health University) ,  Ohye Tamae (Division of Genetic Counseling, Department of Clinical Laboratory Medicine, Graduate School of Health Sciences, Fujita Health University) ,  Ohye Tamae (Molecular Laboratory Medicine, Faculty of Medical Technology, School of Health Sciences, Fujita Health University) ,  Sato Tsutomu (Department of Ethics, Fujita Health University School of Medicine) ,  Inagaki Hidehito (Division of Molecular Genetics, Institute for Comprehensive Medical Sciences, Fujita Health University) ,  Kurahashi Hiroki (Division of Molecular Genetics, Institute for Comprehensive Medical Sciences, Fujita Health University)
資料名： Fujita Medical Journal (Web)  (Fujita Medical Journal (Web))
巻： 2  号： 3  ページ： 59-61(J-STAGE)  発行年： 2016年 
JST資料番号： U0775A  ISSN： 2189-7255  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 女性不妊症の遺伝的病因はほとんど完全には分かっていない。最近...

シソーラス用語： ヒト ,...
準シソーラス用語： JUNO ,...

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著者キーワード (4件)： JUNO ,  IZUMO1 ,  Infertility ,  Sperm-egg fusion

分類 (1件)： 婦人科疾患,妊産婦の疾患  (GS03000D)

引用文献 (13件)：

• 1. de Kretser, DM. Male infertility. Lancet 1997;349:787-90.
• 2. Inoue N, Ikawa M, Isotani A, Okabe M. The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs. Nature 2005;434:234-8.
• 3. Bianchi E, Doe B, Goulding D, Wright GJ. Juno is the egg Izumo receptor and is essential for mammalian fertilization. Nature 2014;508:483-7.
• 4. Inoue N, Hagihara Y, Wright D, Suzuki T, Wada I. Oocyte-triggered dimerization of sperm IZUMO1 promotes sperm-egg fusion in mice. Nat Commun 2015;6:8858.
• 5. Ohto U, Ishida H, Krayukhina E, Uchiyama S, Inoue N, Shimizu T. Structure of IZUMO1-JUNO reveals spermoocyte recognition during mammalian fertilization. Nature 2016;534:566-9.

タイトルに関連する用語 (4件)： 原因 ,  女性不妊症 ,  遺伝子 ,  変異分析