文献

J-GLOBAL ID：201702223884017474   整理番号：17A0972345

稀なFBXO18変異と統合失調症のリスク:2名の親に影響された子孫トリオの全エクソーム解析とそれに続く再解析および症例対照研究

Rare FBXO18 variations and risk of schizophrenia: Whole-exome sequencing in two parent-affected offspring trios followed by resequencing and case-control studies

著者 (14件)： Hoya Satoshi (Department of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Watanabe Yuichiro (Department of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Watanabe Yuichiro (Department of Psychiatry, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, Japan) ,  Hishimoto Akitoyo (Department of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Nunokawa Ayako (Department of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Nunokawa Ayako (Oojima Hospital, Sanjo, Japan) ,  Inoue Emiko (Department of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Igeta Hirofumi (Department of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Otsuka Ikuo (Department of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Shibuya Masako (Department of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Shibuya Masako (Division of Medical Education, Comprehensive Medical Education Center, School of Medicine, Faculty of Medicine, Niigata University, Niigata, Japan) ,  Egawa Jun (Department of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Sora Ichiro (Department of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Someya Toshiyuki (Department of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan)
資料名： Psychiatry and Clinical Neurosciences  (Psychiatry and Clinical Neurosciences)
巻： 71  号： 8  ページ： 562-568  発行年： 2017年08月 
JST資料番号： W1032A  ISSN： 1323-1316  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オーストラリア (AUS)  言語： 英語 (EN)

抄録/ポイント： 目的:希少変異は統合失調症の遺伝的病因において役割を果たして...

シソーラス用語： *統合失調症 ,...
準シソーラス用語： エキソーム解析 ,...

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著者キーワード (5件)： FBXO18 ,  Japanese ,  rare variation ,  schizophrenia ,  whole-exome sequencing

分類 (1件)： 精神科の臨床医学一般  (GR01030T)

引用文献 (23件)：

• Owen MJ, Sawa A, Mortensen PB. Schizophrenia. Lancet 2016; 388: 86-97.
• Kavanagh DH, Tansey KE, O'Donovan MC, Owen MJ. Schizophrenia genetics: Emerging themes for a complex disorder. Mol. Psychiatry 2015; 20: 72-76.
• Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci. Nature 2014; 511: 421-427.
• Kushima I, Aleksic B, Nakatochi M et al. High-resolution copy number variation analysis of schizophrenia in Japan. Mol. Psychiatry 2017; 22: 430-440.
• CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nat. Genet. 2017; 49: 27-35.

タイトルに関連する用語 (7件)： 変異 ,  統合失調症 ,  リスク ,  親 ,  全エクソーム解析 ,  再解析 ,  症例対照研究