文献

J-GLOBAL ID：201702224028036698   整理番号：17A0932545

卵巣がないヤギで黄体形成ホルモン生成を刺激するのに最低限必要な量のTAK-683投与による,卵巣が完全なヤギにおける黄体形成ホルモンの大量生成

An administration of TAK-683 at a minimally effective dose for luteinizing hormone stimulation under the absence of the ovary induces luteinizing hormone surge in ovary-intact goats

著者 (11件)： KANAI Nahoko (Laboratory of Veterinary Reproduction, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan) ,  ENDO Natsumi (Laboratory of Veterinary Reproduction, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan) ,  OHKURA Satoshi (Laboratory of Animal Production Science, Nagoya University, Nagoya 464-8601, Japan) ,  WAKABAYASHI Yoshihiro (Laboratory of Neurobiology, National Institute of Agrobiological Sciences, Ibaraki 305-8602, Japan) ,  MATSUI Hisanori (Takeda Pharmaceutical Company Limited, Kanagawa 251-0012, Japan) ,  MATSUMOTO Hirokazu (Takeda Pharmaceutical Company Limited, Kanagawa 251-0012, Japan) ,  ISHIKAWA Kaori (Takeda Pharmaceutical Company Limited, Kanagawa 251-0012, Japan) ,  TANAKA Akira (Takeda Pharmaceutical Company Limited, Kanagawa 251-0012, Japan) ,  WATANABE Tatsuya (Takeda Pharmaceutical Company Limited, Kanagawa 251-0012, Japan) ,  OKAMURA Hiroaki (Laboratory of Neurobiology, National Institute of Agrobiological Sciences, Ibaraki 305-8602, Japan) ,  TANAKA Tomomi (Laboratory of Veterinary Reproduction, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan)
資料名： Journal of Reproduction and Development  (Journal of Reproduction and Development)
巻： 63  号： 3  ページ： 305-310(J-STAGE)  発行年： 2017年 
JST資料番号： F0766A  ISSN： 0916-8818  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 本研究では,以前の試験で,卵巣を摘出手術したヤギの黄体形成ホ...

シソーラス用語： *ヤギ ,...
準シソーラス用語： *黄体形成ホルモン分泌促進ホルモン ,...

ログイン（無料）して見る     続きはJDreamIII（有料）にて  {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=17A0932545&from=J-GLOBAL&jstjournalNo=F0766A") }}

著者キーワード (4件)： Goats ,  Luteinizing hormone (LH) surge ,  Ovary ,  TAK-683

分類 (2件)： 生殖生理一般  (EJ15010E) ,  羊,山羊  (FD02050F)

物質索引 (4件)： TAK-652 ,  TAK-683 ,  プロゲステロン ,  プロスタグランジンF_2α

引用文献 (27件)：

• 1. Ohkura S, Uenoyama Y, Yamada S, Homma T, Takase K, Inoue N, Maeda K, Tsukamura H. Physiological role of metastin/kisspeptin in regulating gonadotropin-releasing hormone (GnRH) secretion in female rats. Peptides 2009; 30: 49-56.
• 2. Okamura H, Yamamura T, Wakabayashi Y. Kisspeptin as a master player in the central control of reproduction in mammals: an overview of kisspeptin research in domestic animals. Anim Sci J 2013; 84: 369-381.
• 3. Matsui H, Masaki T, Akinaga Y, Kiba A, Takatsu Y, Nakata D, Tanaka A, Ban J, Matsumoto S, Kumano S, Suzuki A, Ikeda Y, Yamaguchi M, Watanabe T, Ohtaki T, Kusaka M. Pharmacologic profiles of investigational kisspeptin/metastin analogues, TAK-448 and TAK-683, in adult male rats in comparison to the GnRH analogue leuprolide. Eur J Pharmacol 2014; 735: 77-85.
• 4. Scott G, Ahmad I, Howard K, MacLean D, Oliva C, Warrington S, Wilbraham D, Worthington P. Double-blind, randomized, placebo-controlled study of safety, tolerability, pharmacokinetics and pharmacodynamics of TAK-683, an investigational metastin analogue in healthy men. Br J Clin Pharmacol 2013; 75: 381-391.
• 5. Ohkura S, Tanaka T, Kuroiwa T, Wakbayashi Y, Ohtaki T, Kusaka M, Okamura H. Effects of investigational metastin/kisspeptin analog, TAK-683, on luteinizing hormone secretion in peripheral plasma, and gonadotropin-releasing hormone secretion in the pituitary portal circulation in goats. In ENDO Annual Meeting; 2011; Boston, USA. Abstract P2-273.

タイトルに関連する用語 (6件)： 卵巣 ,  ヤギ ,  黄体形成ホルモン ,  刺激 ,  量 ,  投与