文献

J-GLOBAL ID：201702257099284323   整理番号：17A0877034

トロンボスポンジン-1の発現は門脈血流閉塞による肝委縮機構に関与している可能性がある

Thrombospondin-1 expression may be implicated in liver atrophic mechanism due to obstructed portal venous flow

著者 (11件)： Hayashi Hiromitsu (Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Hayashi Hiromitsu (Department of Surgery, Saiseikai Kumamoto Hospital, Kumamoto, Japan) ,  Kuroki Hideyuki (Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Higashi Takaaki (Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Takeyama Hideaki (Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Yokoyama Naomi (Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Okabe Hirohisa (Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Nitta Hidetoshi (Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Beppu Toru (Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan) ,  Takamori Hiroshi (Department of Surgery, Saiseikai Kumamoto Hospital, Kumamoto, Japan) ,  Baba Hideo (Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan)
資料名： Hepatology Research  (Hepatology Research)
巻： 47  号： 8  ページ： 803-812  発行年： 2017年07月 
JST資料番号： W1284A  ISSN： 1386-6346  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オーストラリア (AUS)  言語： 英語 (EN)

抄録/ポイント： 目的:肝臓は,血流状態により再生性変化も萎縮性変化も起こり得...

シソーラス用語： ヒト ,...
準シソーラス用語： *トロンボスポンジン-1 ,...

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著者キーワード (4件)： atrophic liver ,  obstructed portal flow ,  Smad signal ,  thrombospondin-1

分類 (2件)： 消化器の疾患  (GH03000W) ,  蛋白質・ペプチド一般  (EB03010N)

引用文献 (20件)：

• Hayashi H, Beppu T, Sugita H et al. Increase in the serum bile acid level predicts the effective hypertrophy of the nonembolized hepatic lobe after right portal vein embolization. World J Surg 2009; 33: 1933-40.
• Hayashi H, Beppu T, Sugita H et al. Serum HGF and TGF-β1 levels after right portal vein embolization. Hepatol Res 2010; 40: 311-7.
• Crawford SE, Stellmach V, Murphy-Ullrich JE et al. Thrombospondin-1 is a major activator of TGF-β1 in vivo. Cell 1998; 93: 1159-70.
• Adams JC. Thrombospondins: multifunctional regulators of cell interactions. Annu Rev Cell Dev Biol 2001; 17: 25-51.
• Kyriakides TR, Madauchlan S. The role of thrombospondins in wound healing, ischemia, and the foreign body reaction. J Cell Commun Signal 2009; 3: 215-25.

タイトルに関連する用語 (6件)： トロンボスポンジン-1 ,  発現 ,  門脈血流 ,  閉塞 ,  肝委縮 ,  可能性