文献

J-GLOBAL ID：201702275461564261   整理番号：17A0136219

セロトニン5-HT2B受容体拮抗作用は過酸化水素に曝露したPC12細胞を保護する基本である

Serotonin 5-HT2B receptor antagonism is fundamental for protecting PC12 cells exposed to hydrogen peroxide

著者 (12件)： Takayanagi Takeshi (Division of Endocrinology and Metabolism, Department of Internal Medicine, Fujita Health University School of Medicine) ,  Kaneko S. Yoko (Department of Physiology, Fujita Health University School of Medicine) ,  Nagasaki Hiroshi (Department of Physiology, Fujita Health University School of Medicine) ,  Kodani Yu ,  Nakashima Akira ,  Mori Keiji (Department of Health Sciences, Kinjo University) ,  Suzuki Atsushi (Division of Endocrinology and Metabolism, Department of Internal Medicine, Fujita Health University School of Medicine) ,  Itoh Mitsuyasu (Division of Endocrinology and Metabolism, Department of Internal Medicine, Fujita Health University School of Medicine) ,  Kondo Kazunao (Department of Pharmacology, Fujita Health University School of Medicine) ,  Nagatsu Toshiharu (Department of Pharmacology, Fujita Health University School of Medicine) ,  Ota Miyuki (Department of Psychiatry, Tosei General Hospital) ,  Ota Akira (Department of Physiology, Fujita Health University School of Medicine)
資料名： Fujita Medical Journal (Web)  (Fujita Medical Journal (Web))
巻： 1  号： 1  ページ： 1-5(J-STAGE)  発行年： 2015年 
JST資料番号： U0775A  ISSN： 2189-7255  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 目的:以前の研究に基づくと,アリピプラゾールは過酸化水素(H...

シソーラス用語： PC12細胞 ,...

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著者キーワード (5件)： hydrogen peroxide ,  PC12 cells ,  aripiprazole ,  serotonin 5-HT2B-receptor ,  dopamine D1-receptor

分類 (1件)： 向精神薬の基礎研究  (GW03100Y)

物質索引 (1件)： アリピプラゾール

引用文献 (36件)：

• 1. Burris KD, Molski TF, Xu C, Ryan E, Tottori K, Kikuchi T, Yocca FD, Molinoff PB. Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors. J Pharmacol Exp Ther 2002;302:381-9.
• 2. Jordan S, Koprivica V, Chen R, Tottori K, Kikuchi T, Altar CA. The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT1A receptor. Eur J Pharmacol 2002;441:137-40.
• 3. Keltner NL, Johnson V. Biological perspectives. Aripiprazole: a third generation of antipsychotics begins? Perspect Psychiatr Care 2002;38:157-9.
• 4. Roth BL, Ciaranello RD, Meltzer HY. Binding of typical and atypical antipsychotic agents to transiently expressed 5-HT1C receptors. J Pharmacol Exp Ther 1992;260:1361-5.
• 5. Shapiro DA, Renock S, Arrington E, Chiodo LA, Liu LX, Sibley DR, Roth BL, Mailman R. Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology. Neuropsychopharmacology 2003;28:1400-11.

タイトルに関連する用語 (6件)： セロトニン ,  5-HT2B受容体 ,  拮抗作用 ,  過酸化水素 ,  曝露 ,  PC12細胞