謝家暉

Tse Ka Fai William

所属機関・部署：
職名：准教授

研究分野 (1件)：地球生命科学

研究キーワード (4件)： Deubiquitinase , Fish Osmoregulation , Disease model and mechanism , Developmental Toxicology

競争的資金等の研究課題 (31件)：

2023 - 2025 Unfolding the pathogenesis of craniofacial related intractable diseases by zebrafish model
2022 - 2025 Glutathione modulates the extracellular matrix organization of craniofacial neural crest cells in Type 3 POLR`C Treacher Collins syndrome
2022 - 2024 The impact of microplastics on brain health and reproductive system health and the damage of barrier function
2022 - 2023 Effect of osmotic stress on gill micriobiota in medaka
2020 - 2023 The role of polr1c in regulating endodermal cells in Type 3 Treacher Collins syndrome

2020 - 2022 The osmoregulatory mechanism in medaka

2020 - 2022 Effects of plastic microparticles and their environmental pollutants enrichment on reproductive ability of parents and offspring

2019 - 2020 The role of polr1c in regulating endodermal cells in Type 3 Treacher Collins syndrome

2019 - 2020 The osmoregulatory roles of Ostf1b in medaka

2019 - 2020 Triclosan: a risk factor of fatty liver disease

2018 - 2019 水環境の金属酸化物ナノ粒子の発生毒性影響評価

2018 - 2019 Triclosan: a risk factor of fatty liver disease

2018 - 2019 The osmoregulatory roles of Ostf1b in medaka

2018 - 2019 Generation of osmotic stress transcription factor 1b knockout medaka for fish osmoregulation studies

2017 - 2019 モデル動物を用いた、3 型トレチャーコリンズ症候群に対する抗酸化剤の治療効果の検討

2018 - 2019 The emerging craniofacial developmental roles of polr1c in Treacher Collins Syndrome

2017 - 2019 The potential use of antioxidant to treat the POLR1C-dependent Type 3 Treacher Collins Syndrome.

2017 - 2018 ゼブラフィッシュ胚を使用した水質検査ガイドラインの確立

2017 - 2018 Generation of knockout medaka for fish osmoregulation studies

2017 - 2018 ゼブラフィッシュ胚を使用した水質検査ガイドラインの確立/To establish the guideline of using zebrafish embryos to monitor the water quality

2015 - 2016 Screening for transgenic craniofacial developmental model for live-imaging.

2015 - 2016 Role of deubiquitylating enzyme, cops6, in zebrafish craniofacial palatogenesis.

2014 - 2016 To Define the Effects of Endocrine-Disrupting Chemicals on Gonadal Sex Development.

2013 - 2016 Start-up

2015 - 2015 The Role of DUBs in Cancer Metastasis.

2015 - 2015 Characterization of cpt1a in liver development and the generation of cpt1a transgenic zebrafish for environmental toxicology screening.

2014 - 2014 Functional Studies of polr1c in Facial Development.

2014 - 2014 Functions of Deubiquitylating Enzymes on Craniofacial Development.

2013 - 2013 The Characterization of Novel mib Alleles.

2013 - 2013 Characterization of Treacher Collins syndrome using zebrafish mutant polr1c line.

2009 - 2011 Osmoregulation and Osmosensing mechanisms in eel mitochondria-rich cells

全件表示

論文 (78件)：

Cristian Prieto-Garcia, Vigor Matkovic, Thorsten Mosler, Congxin Li, Jie Liang, James A Oo, Felix Haidle, Igor Mačinković, Alfredo Cabrera-Orefice, Rayene Berkane, et al. Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy. Science (New York, N.Y.). 2024. 386. 6723. 768-776
Zulvikar Syambani Ulhaq, May-Su You, Taijiro Yabe, Shinji Takada, Jen-Kun Chen, Yukiko Ogino, Yun-Jin Jiang, William Ka Fai Tse. Fgf8 contributes to the pathogenesis of Nager syndrome. International journal of biological macromolecules. 2024. 280. Pt 3. 135692-135692
Ziyi Lin, Zijie Li, Shuqin Ji, Hoi Shing Lo, Baki Billah, Ayesha Sharmin, Xiaofang Han, Wing-Yee Lui, William Ka Fai Tse, James Kar-Hei Fang, et al. Size-dependent deleterious effects of nano- and microplastics on sperm motility. Toxicology. 2024. 506. 153834-153834
Wei Yan, Zi-Jie Li, Zi-Yi Lin, Shu-Qin Ji, William Ka Fai Tse, Zhi-Qiang Meng, Chang Liu, Lei Li. Microplastic exposure disturbs sleep structure, reduces lifespan, and decreases ovary size in Drosophila melanogaster. Zoological research. 2024. 45. 4. 805-820
Keng Po Lai, Delbert Almerick T Boncan, Xian Qin, Ting Fung Chan, William Ka Fai Tse. Roles and occurrences of microbiota in the osmoregulatory organs, gills and gut, in marine medaka upon hypotonic stress. Comparative biochemistry and physiology. Part D, Genomics & proteomics. 2024. 52. 101285-101285

書籍 (4件)：

Advances in Environmental Research
Nova Science Publishers, New York 2020
Advances in medicine and biology
Nova Science Publishers, New York 2019
Zebrafish: Topics in Reproduction and Development
Nova Science Publishers, New York 2014
Eel: Physiology, Habitat and Conservation
Nova Science Publishers, New York 2012

講演・口頭発表等 (22件)：

Zebrafish as a toxicant screening model
(Key Laboratory of Environmental Pollution and Integrative Omics, Guilin Medical University, China 2022)
The pathogenesis of Type 3 Treacher Collins Syndrome
(Institute of Molecular and Cellular Regulation, Gunma University 2018)
Current trend in developmental toxicology and the application of omics
(The 53rd Annual Meeting of the Japanese Society of Developmental Biologists (JSDB) 2020)
Unfolding the disease mechanism of Type 3 Treacher Collins syndrome by zebrafish model
(2019 International Zebrafish Conference 2019)
The developmental toxicity of metal nanoparticle in zebrafish
(The 52nd Annual Meeting of the Japanese Society of Developmental Biologists (JSDB) 2019)

経歴 (5件)：

2016/04 - 現在九州大学農学研究院
2012/06 - 2016/03 香港浸会大学生物学部
2011/09 - 2012/06 ハーバード大学/マサチューセッツ総合病院医学部
2009/09 - 2011/04 東京大学大気海洋研究所
2007/11 - 2009/09 シンガポール A*STAR 分子細胞生物学研究所

委員歴 (7件)：

2023/11 - 現在 BMC Biology Associate Editor
2020/08 - 現在 Translational Oncology Advisory Board
2019/10 - 現在 Antibiotics Topic Editor
2018/05 - 現在 BMC Genomics Associate Editor
2022/04 - 2026/03 九州大学九州大学外国人教員アドバイザリーグループ SHARE-Q International Advisory Group (SIAG)

全件表示

受賞 (4件)：

2009/09 - The Japan Society for the Promotion of Science (JSPS) JSPS Postdoctoral Fellowship
2009/05 - The Asia-Pacific Developmental Biology Network (APDBN) APDBN Travel Award
2006/01 - 7th International Congress on the Biology of Fish Student Travel Award
2004/09 - Hong Kong Baptist University Postgraduate studentship

所属学会 (3件)：

The Asia-Pacific Developmental Biology Network , Hong Kong Society for Developmental Biology , Japanese Society of Developmental Biology

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