研究者

J-GLOBAL ID：201801012194906559 更新日: 2023年03月22日

角南明彦

Sunami Akihiko

所属機関・部署：
職名：教授

研究分野 (1件)：薬系衛生、生物化学

研究キーワード (1件)：イオンチャネル

競争的資金等の研究課題 (1件)：

2002 - 2003 Naチャネルポア内側部の構造決定

論文 (43件)：

Nakagawa H, Munakata T, Sunami A. Mexiletine Block of Voltage-Gated Sodium Channels: Isoform- and State-Dependent Drug-Pore Interactions. Molecular pharmacology. 2019. 95. 3. 236-244
Akihiko Sunami. Drug-Binding Sites of Cardiac Sodium Channel. journal of arrhythmia. 2011. 27. 4. 241
Asami Kaihara, Akihiko Sunami, Junko Kurokawa, Tetsushi Furukawa. A Genetically Encoded Bioluminescent Indicator for the Sodium Channel Activity in Living Cells. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2009. 131. 12. 4188-+
Naomasa Makita, Elijah Behr, Wataru Shimizu, Minoru Horie, Akihiko Sunami, Lia Crotti, Eric Schulze-Bahr, Shigetomo Fukuhara, Naoki Mochizuki, Takeru Makiyama, et al. The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome. JOURNAL OF CLINICAL INVESTIGATION. 2008. 118. 6. 2219-2229
A Sunami, A Tracey, IW Glaaser, GM Lipkind, DA Hanck, HA Fozzard. Accessibility of mid-segment domain IVS6 residues of the voltage-gated Na+ channel to methanethiosulfonate reagents. JOURNAL OF PHYSIOLOGY-LONDON. 2004. 561. 2. 403-413

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MISC (17件)：

中川博揮, 宗像達夫, 角南明彦. 抗不整脈薬によるヒト心筋Naチャネル抑制作用のチャネルポア分子構造基盤. 日本薬理学会関東部会プログラム・要旨集. 2016. 134th. 63
Asami Kaihara, Akihiko Sunami, Junko Kurokawa, Tetsushi Furukawa. A GENETICALLY ENCODED BIOLUMINESCENT INDICATOR FOR THE SODIUM CHANNEL IN LIVING CELLS. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2009. 59. 250-250
Sasaki Koji, Makita Naomasa, Shirai Nobumasa, Yokoi Hisataka, Kitabatake Akira, Sunami Akihiko, Kimura Akinori, Hiraoka Masayasu. An SCN5A Mutation Associated With Idiopathic Ventricular Fibrillation Alters The Na^+ Channel Pore Structure And Responses To Antiarrhythmic Drugs. Circulation journal : official journal of the Japanese Circulation Society. 2002. 66. 118-118
A Sunami, T Sawanobori, HA Fozzard. Cysteine scanning analysis of domain IVS6 in sodium channel. JAPANESE JOURNAL OF PHARMACOLOGY. 2002. 88. 215P-215P
A Sunami, IW Glaaser, GM Lipkind, HA Fozzard. The structure and orientation of domain IVS6 in sodium channel determined by cysteine scanning mutagenesis. CIRCULATION. 2001. 104. 17. 216-216

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書籍 (3件)：

Advances in Health and Disease (vol. 63)
Nova Science 2023
Encyclopedia of Molecular Pharmacology, 3rd Edition
Springer 2021
不整脈学
南江堂 2012

講演・口頭発表等 (2件)：

Differences of pore structures between prokaryotic and eukaryotic voltage-gated sodium channels
(Biophysical Society Annual Meeting 2015)
Drug-binding sites of cardiac sodium channel
(4th Asia Pacific Heart Rhythm Society Scientific Session 2011)

学位 (1件)：

薬学博士 (岡山大学大学院自然科学研究科)

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