文献

J-GLOBAL ID：201802212114680697   整理番号：18A0134038

ENIGMAと個人:世界35カ国における脳に影響を及ぼす因子の予測【Powered by NICT】

ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide

著者 (106件)： Thompson Paul M. (Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Marina del Rey 90292, USA) ,  Thompson Paul M. (Departments of Neurosciences, Radiology, Psychiatry, and Cognitive Science, University of California, San Diego 92093, CA, USA) ,  Andreassen Ole A. (NORMENT-KG Jebsen Centre, Institute of Clinical Medicine, University of Oslo, Oslo 0315, Norway) ,  Andreassen Ole A. (NORMENT-KG Jebsen Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo 0315, Norway) ,  Arias-Vasquez Alejandro (Donders Center for Cognitive Neuroscience, Departments of Psychiatry, Human Genetics & Cognitive Neuroscience, Radboud University Medical Center, Nijmegen 6525, The Netherlands) ,  Bearden Carrie E. (Department of Psychiatry & Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA) ,  Bearden Carrie E. (Dept. of Psychology, University of California, Los Angeles, CA 90095, USA) ,  Bearden Carrie E. (Brain Research Institute, University of California, Los Angeles, CA 90095, USA) ,  Boedhoe Premika S. (Department of Anatomy & Neurosciences, VU University Medical Center, Amsterdam, The Netherlands) ,  Boedhoe Premika S. (Department of Psychiatry, VU University Medical Center (VUMC), Amsterdam, The Netherlands) ,  Boedhoe Premika S. (Neuroscience Campus Amsterdam, VU/VUMC, Amsterdam, The Netherlands) ,  Brouwer Rachel M. (Brain Center Rudolf Magnus, Department of Psychiatry, UMC Utrecht, Utrecht 3584 CX, The Netherlands) ,  Buckner Randy L. (Department of Psychiatry, Massachusetts General Hospital, Boston 02114, USA) ,  Buitelaar Jan K. (Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen 6500 HB, The Netherlands) ,  Buitelaar Jan K. (Department of Psychology, Center for Brain Science, Harvard University, Cambridge, MA 02138, USA) ,  Bulayeva Kazima B. (N.I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Gubkin str. 3, Moscow 119991, Russia) ,  Cannon Dara M. (National Institute of Mental Health Intramural Research Program, Bethesda 20892, USA) ,  Cannon Dara M. (Neuroimaging & Cognitive Genomics Centre (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, H91 TK33 Galway, Ireland) ,  Cohen Ronald A. (Institute on Aging, University of Florida, Gainesville, FL 32611, USA) ,  Conrod Patricia J. (Department of Psychological Medicine and Psychiatry, Section of Addiction, King’s College London, University of London, UK) ,  Dale Anders M. (Departments of Neurosciences, Radiology, Psychiatry, and Cognitive Science, University of California, San Diego, La Jolla, CA 92093-0841, USA) ,  Deary Ian J. (Centre for Cognitive Ageing and Cognitive Epidemiology, Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK) ,  Dennis Emily L. (Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Marina del Rey 90292, USA) ,  de Reus Marcel A. (Brain Center Rudolf Magnus, Department of Psychiatry, UMC Utrecht, Utrecht 3584 CX, The Netherlands) ,  Desrivieres Sylvane (MRC-SGDP Centre, Institute of Psychiatry, King’s College London, London SE5 8AF, UK) ,  Dima Danai (Institute of Psychiatry, Psychology and Neuroscience, King’s College London, UK) ,  Dima Danai (Clinical Neuroscience Studies (CNS) Center, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, USA) ,  Donohoe Gary (Neuroimaging and Cognitive Genomics center (NICOG), School of Psychology, National University of Ireland, Galway, Ireland) ,  Fisher Simon E. (Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen 6525 XD, The Netherlands) ,  Fisher Simon E. (Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen 6500 HB, The Netherlands) ,  Fouche Jean-Paul (Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa) ,  Francks Clyde (Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen 6525 XD, The Netherlands) ,  Francks Clyde (Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen 6500 HB, The Netherlands) ,  Frangou Sophia (Clinical Neuroscience Studies (CNS) Center, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, USA) ,  Franke Barbara (Department of Human Genetics, Radboud University Medical Center, Nijmegen 6525, The Netherlands) ,  Franke Barbara (Department of Psychiatry, Radboud University Medical Center, Nijmegen 6525, The Netherlands) ,  Franke Barbara (Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen 6500 HB, The Netherlands) ,  Ganjgahi Habib (Department of Statistics, The University of Warwick, Coventry, UK) ,  Garavan Hugh (Psychiatry Department, University of Vermont, VT, USA) ,  Glahn David C. (Department of Psychiatry, Yale University, New Haven, CT 06511, USA) ,  Glahn David C. (Olin Neuropsychiatric Research Center, Hartford, CT 06114, USA) ,  Grabe Hans J. (Department of Psychiatry, University Medicine Greifswald, Greifswald 17489, Germany) ,  Grabe Hans J. (Department of Psychiatry and Psychotherapy, HELIOS Hospital, Stralsund 18435, Germany) ,  Guadalupe Tulio (Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen 6525 XD, The Netherlands) ,  Guadalupe Tulio (International Max Planck Research School for Language Sciences, Nijmegen 6525 XD, The Netherlands) ,  Gutman Boris A. (Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Marina del Rey 90292, USA) ,  Hashimoto Ryota (Molecular Research Center for Children’s Mental Development, United Graduate School of Child Development, Osaka University, Japan) ,  Hibar Derrek P. (Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Marina del Rey 90292, USA) ,  Holland Dominic (Departments of Neurosciences, Radiology, Psychiatry, and Cognitive Science, University of California, San Diego, La Jolla, CA 92093-0841, USA) ,  Hoogman Martine (Department of Human Genetics, Radboud University Medical Center, Nijmegen 6525, The Netherlands) ,  Hoogman Martine (Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen 6500 HB, The Netherlands) ,  Pol Hilleke E. Hulshoff (Brain Center Rudolf Magnus, Department of Psychiatry, UMC Utrecht, Utrecht 3584 CX, The Netherlands) ,  Hosten Norbert (Department of Radiology University Medicine Greifswald, Greifswald 17475, Germany) ,  Jahanshad Neda (Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Marina del Rey 90292, USA) ,  Kelly Sinead (Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Marina del Rey 90292, USA) ,  Kochunov Peter (Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21201, USA) ,  Kremen William S. (Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA) ,  Lee Phil H. (Center for Human Genetic Research, Massachusetts General Hospital, USA) ,  Lee Phil H. (Department of Psychiatry, Harvard Medical School, USA) ,  Lee Phil H. (Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA) ,  Mackey Scott (Department of Psychiatry, University of Vermont, Burlington 05401, VT, USA) ,  Martin Nicholas G. (QIMR Berghofer Medical Research Institute, Brisbane 4006, Australia) ,  Mazoyer Bernard (Groupe d’imagerie Neurofonctionnelle, UMR5296 CNRS CEA Universite de Bordeaux, France) ,  McDonald Colm (Neuroimaging & Cognitive Genomics Centre (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, H91 TK33 Galway, Ireland) ,  Medland Sarah E. (QIMR Berghofer Medical Research Institute, Brisbane 4006, Australia) ,  Morey Rajendra A. (Duke Institute for Brain Sciences, Duke University, NC 27710, USA) ,  Nichols Thomas E. (Department of Statistics & WMG, University of Warwick, Coventry CV4 7AL, UK) ,  Nichols Thomas E. (FMRIB Centre, University of Oxford, Oxford OX3 9DU, UK) ,  Paus Tomas (Rotman Research Institute, Baycrest, Toronto, ON, Canada) ,  Paus Tomas (Departments of Psychology and Psychiatry, University of Toronto, Toronto, Canada) ,  Paus Tomas (Child Mind Institute, NY, USA) ,  Pausova Zdenka (The Hospital for Sick Children, University of Toronto, Toronto, Canada) ,  Pausova Zdenka (Departments of Physiology and Nutritional Sciences, University of Toronto, Toronto, Canada) ,  Schmaal Lianne (Department of Psychiatry, VU University Medical Center (VUMC), Amsterdam, The Netherlands) ,  Schmaal Lianne (Neuroscience Campus Amsterdam, VU/VUMC, Amsterdam, The Netherlands) ,  Schumann Gunter (MRC-SGDP Centre, Institute of Psychiatry, King’s College London, London SE5 8AF, UK) ,  Shen Li (Center for Neuroimaging, Dept. of Radiology and Imaging Sciences, Indiana University School of Medicine, 355 W. 16th Street, Suite 4100, Indianapolis, IN 46202, USA) ,  Shen Li (Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, 355 W. 16th Street, Suite 4100, Indianapolis, IN 46202, USA) ,  Sisodiya Sanjay M. (Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London WC1N 3BG, UK and Epilepsy Society, Bucks, UK) ,  Smit Dirk J.A. (Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands) ,  Smit Dirk J.A. (Neuroscience Campus Amsterdam, VU/VUMC, Amsterdam, The Netherlands) ,  Smoller Jordan W. (Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, USA) ,  Stein Dan J. (Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa) ,  Stein Dan J. ,  Stein Jason L. (Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Marina del Rey 90292, USA) ,  Stein Jason L. ,  Toro Roberto ,  Turner Jessica A. ,  van den Heuvel Martijn P. (Brain Center Rudolf Magnus, Department of Psychiatry, UMC Utrecht, Utrecht 3584 CX, The Netherlands) ,  van den Heuvel Odile L. (Department of Anatomy & Neurosciences, VU University Medical Center, Amsterdam, The Netherlands) ,  van den Heuvel Odile L. (Department of Psychiatry, VU University Medical Center (VUMC), Amsterdam, The Netherlands) ,  van den Heuvel Odile L. (Neuroscience Campus Amsterdam, VU/VUMC, Amsterdam, The Netherlands) ,  van Erp Theo G.M. ,  van Rooij Daan (Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen 6500 HB, The Netherlands) ,  Veltman Dick J. (Department of Anatomy & Neurosciences, VU University Medical Center, Amsterdam, The Netherlands) ,  Veltman Dick J. (Department of Psychiatry, VU University Medical Center (VUMC), Amsterdam, The Netherlands) ,  Veltman Dick J. (Neuroscience Campus Amsterdam, VU/VUMC, Amsterdam, The Netherlands) ,  Walter Henrik ,  Wang Yalin ,  Wardlaw Joanna M. ,  Wardlaw Joanna M. (Centre for Cognitive Ageing and Cognitive Epidemiology, Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK) ,  Wardlaw Joanna M. ,  Whelan Christopher D. (Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Marina del Rey 90292, USA) ,  Wright Margaret J. ,  Ye Jieping ,  Ye Jieping
資料名： NeuroImage  (NeuroImage)
巻： 145  号： PB  ページ： 389-408  発行年： 2017年 
JST資料番号： W3139A  ISSN： 1053-8119  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 本レビューでは,ENIGMAコンソーシアム(http://enigma.ini.usc.edu)による最近の研究を考察する500以上の科学者のグローバルアライアンスは,脳画像,臨床的および遺伝的データを解析する集団的35か国の200施設に広がる。脳対策に対する遺伝的影響を検出するために形成された,ENIGMAをプールすることにより12種類の主要な脳疾患研究及び脳データを比較するワーキンググループを30以上に成長している。今日までの最大の神経画像研究のいくつかでは統合失調症および大うつ病-ENIGMAのは世界的に一致していることを脳に複製可能な疾患効果だけでなく,疾患効果を調節する因子を見出した。ADNI,電荷,IMAGEN等~11略語を含む他の共同体との提携:ADNI,アルツハイマー病神経画像処理イニシアティブ(http://www.adni info.org)CHARGE,コホート心臓と老化研究のためのゲノム疫学コンソーシアム(http://www.chargeconsortium.com)IMAGEN,IMAging GENeticsコンソーシアム(http://www.imagen europe.com)。ENIGMAの30,000MRIスキャン上の番号付け-ゲノムスクリーンは脳容積に影響する少なくとも8遺伝子座を明らかにした。遺伝子所見,ENIGMAの下流では一般的にこれらの個々の変異体および遺伝的変異体は,疾患の脳とリスクの両方にどのように影響するか明らかにした。ENIGMAコンソーシアムは,個々の脳スキャンとゲノムデータを結びつける将来予測因子として役立つであろうことを脳構造および機能に影響を及ぼすことを発見する因子である。対象の特定のグループの正常な発達または加齢からのずれの検出に有用であることを脳施策-十千人のからに関する標準的なデータの大プールを発生している。個々の課題と新しいコホートにこれらの予測因子を適用する際の課題と機会と同様に,著者らはこれまで謎の努力において学んだ教訓を論じた。Copyright 2018 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【Powered by NICT】

シソーラス用語： 老化 ,  コミュニティ ,  遺伝的影響 ,  母集団 ,  Alzheimer病 ,  遺伝子 ,  *統合失調症 ,  走査 ,  遺伝
準シソーラス用語： 予測因子 ,  脳容積 ,  大欝病性障害 ,  ニューロイメージング ,  脳画像 ,  コンソーシアム , 【Automatic Indexing@JST】

分類 (4件)： 精神障害の診断  (GR02000T) ,  精神障害  (GR03000A) ,  精神科の基礎医学  (GR01020I) ,  精神科の臨床医学一般  (GR01030T)

タイトルに関連する用語 (5件)： 個人 ,  世界 ,  脳 ,  因子 ,  予測