文献

J-GLOBAL ID：201802213431237459   整理番号：18A1010925

無菌X-SCIDブタの作製と飼育

Production and rearing of germ-free X-SCID pigs

著者 (17件)： Hara Hiromasa (Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan) ,  Shibata Hiroaki (Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan) ,  Shibata Hiroaki (Center for Development of Advanced Medical Technology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan) ,  Nakano Kazuaki (Department of Life Sciences, School of Agriculture, Meiji University, 1-1-1 Higashi-Mita, Tama, Kawasaki, Kanagawa 214-8571, Japan) ,  Abe Tomoyuki (Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan) ,  Abe Tomoyuki (Center for Development of Advanced Medical Technology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan) ,  Uosaki Hideki (Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan) ,  Uosaki Hideki (Center for Development of Advanced Medical Technology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan) ,  Ohnuki Takahiro (Center for Development of Advanced Medical Technology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan) ,  Hishikawa Shuji (Center for Development of Advanced Medical Technology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan) ,  Kunita Satoshi (Center for Development of Advanced Medical Technology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan) ,  Watanabe Masahito (Meiji University International Institute for Bio-Resource Research, 1-1-1 Higashi-Mita, Tama, Kawasaki, Kanagawa 214-8571, Japan) ,  Nureki Osamu (Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Nagashima Hiroshi (Department of Life Sciences, School of Agriculture, Meiji University, 1-1-1 Higashi-Mita, Tama, Kawasaki, Kanagawa 214-8571, Japan) ,  Nagashima Hiroshi (Meiji University International Institute for Bio-Resource Research, 1-1-1 Higashi-Mita, Tama, Kawasaki, Kanagawa 214-8571, Japan) ,  Hanazono Yutaka (Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan) ,  Hanazono Yutaka (Center for Development of Advanced Medical Technology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan)
資料名： Experimental Animals  (Experimental Animals)
巻： 67  号： 2  ページ： 139-146(J-STAGE)  発行年： 2018年 
JST資料番号： Z0755A  ISSN： 1341-1357  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： インターロイキン-2受容体γ鎖遺伝子(IL2RG遺伝子)の突...

シソーラス用語： *ブタ ,...
準シソーラス用語： IL2RG遺伝子 ,...

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著者キーワード (4件)： 無菌ブタ ,  ノトビオート ,  インターロイキン2受容体γ鎖遺伝子(IL2rg)ノックアウト ,  X連鎖重症複合免疫不全症(X-SCID)

分類 (3件)： 免疫性疾患・アレルギー性疾患一般  (GD04010C) ,  実験用生物  (EA03070Y) ,  遺伝学研究法  (EC01020N)

引用文献 (24件)：

• 1. Buckley R.H. 2004. Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution. Annu. Rev. Immunol. 22: 625-655.
• 2. Cao X., Shores E.W., Hu-Li J., Anver M.R., Kelsall B.L., Russell S.M., Drago J., Noguchi M., Grinberg A., Bloom E.T., Paul W.E., Katz S.I., Love P.E., and Leonard W.J. 1995. Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain. Immunity 2: 223-238.
• 3. Charbonneau M.R., O’Donnell D., Blanton L.V., Totten S.M., Davis J.C., Barratt M.J., Cheng J., Guruge J., Talcott M., Bain J.R., Muehlbauer M.J., Ilkayeva O., Wu C., Struckmeyer T., Barile D., Mangani C., Jorgensen J., Fan Y.M., Maleta K., Dewey K.G., Ashorn P., Newgard C.B., Lebrilla C., Mills D.A., and Gordon J.I. 2016. Sialylated milk oligosaccharides promote microbiota-dependent growth in models of infant undernutrition. Cell 164: 859-871.
• 4. Fujishiro S.H., Nakano K., Mizukami Y., Azami T., Arai Y., Matsunari H., Ishino R., Nishimura T., Watanabe M., Abe T., Furukawa Y., Umeyama K., Yamanaka S., Ema M., Nagashima H., and Hanazono Y. 2013. Generation of naive-like porcine-induced pluripotent stem cells capable of contributing to embryonic and fetal development. Stem Cells Dev. 22: 473-482.
• 5. Giovanella B.C., Stehlin J.S., Wall M.E., Wani M.C., Nicholas A.W., Liu L.F., Silber R., and Potmesil M. 1989. DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts. Science 246: 1046-1048.

タイトルに関連する用語 (5件)： 無菌 ,  SCID ,  ブタ ,  作製 ,  飼育