文献

J-GLOBAL ID：201802223301240457   整理番号：18A1014088

SHRSP5/Dmcrラットにおいて高脂肪および高コレステロール食は,心臓線維症,血管内皮および左心室拡張機能障害を誘発する

A High-Fat and High-Cholesterol Diet Induces Cardiac Fibrosis, Vascular Endothelial, and Left Ventricular Diastolic Dysfunction in SHRSP5/Dmcr Rats

著者 (14件)： Watanabe Shogo (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Kumazaki Shota (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Kusunoki Katsuhiro (Department of Medical Technology, Faculty of Health Sciences, Okayama University) ,  Inoue Terumi (Department of Medical Technology, Faculty of Health Sciences, Okayama University) ,  Maeda Yui (Department of Medical Technology, Faculty of Health Sciences, Okayama University) ,  Usui Shinichi (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Shinohata Ryoko (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Ohtsuki Takashi (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Hirohata Satoshi (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Kusachi Shozo (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Kitamori Kazuya (College of Human Life and Environment, Kinjo Gakuin University) ,  Mori Mari (Institute for World Health Development, Mukogawa Women’s University) ,  Yamori Yukio (Institute for World Health Development, Mukogawa Women’s University) ,  Oka Hisao (Department of Medical Technology, Graduate School of Health Sciences, Okayama University)
資料名： Journal of Atherosclerosis and Thrombosis (Web)  (Journal of Atherosclerosis and Thrombosis (Web))
巻： 25  号： 5  ページ： 439-453(J-STAGE)  発行年： 2018年 
JST資料番号： U0153A  ISSN： 1880-3873  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 目的:非アルコール性脂肪性肝炎(NASH)はメタボリックシン...

シソーラス用語： 病態モデル ,...
準シソーラス用語： *拡張機能障害 ,...

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著者キーワード (6件)： 動脈硬化 ,  非アルコール性脂肪肝炎 ,  SHRSP5/DMCR ,  内皮機能 ,  高脂肪 ,  高コレステロール食

分類 (3件)： 循環系の基礎医学  (GJ01020K) ,  代謝異常・栄養性疾患一般  (GD05010J) ,  循環系一般  (EJ04010S)

引用文献 (53件)：

• 1) Bentzon JF, Otsuka F, Virmani R, Falk E: Mechanisms of plaque formation and rupture. Circ Res, 2014; 114: 1852-1866
• 2) Kunimasa K, Yoshitomi H, Miura C, Mori H, Tsuchikura S, Ikeda K, Gao M, Yamori Y, Mori M: High susceptibility of obese hypertensive SHRSP.Z-Lepr(fa) /IzmDmcr rats to lipid deposition in the mesenteric artery. Clin Exp Pharmacol Physiol, 2010; 37: 1102-1104
• 3) Gordts PL, Bartelt A, Nilsson SK, Annaert W, Christoffersen C, Nielsen LB, Heeren J, Roebroek AJ: Impaired LDL receptor-related protein 1 translocation correlates with improved dyslipidemia and atherosclerosis in apoE-deficient mice. PLoS One, 2012; 7: e38330
• 4) Kitamori K, Naito H, Tamada H, Kobayashi M, Miyazawa D, Yasui Y, Sonoda K, Tsuchikura S, Yasui N, Ikeda K, Moriya T, Yamori Y, Nakajima T: Development of novel rat model for high-fat and high-cholesterol dietinduced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr. Environ Health Prev Med, 2012; 17: 173-182
• 5) Yamori Y, Kitamura Y, Nara Y, Iritani N: Mechanism of hypercholesterolemia in arteriolipidosis-prone rats (ALR). Jpn Circ J, 1981; 45: 1068-1073

タイトルに関連する用語 (8件)： ラット ,  脂肪 ,  高コレステロール食 ,  心臓線維症 ,  血管内皮 ,  左心室拡張 ,  機能障害 ,  誘発