文献

J-GLOBAL ID：201802257017745781   整理番号：18A0556889

タバコ煙抽出物は甲状腺ホルモンとその受容体が媒介する転写活性を撹乱する

Cigarette Smoke Extract Disrupts Transcriptional Activities Mediated by Thyroid Hormones and Its Receptors

著者 (9件)： Hayashi Misa (Department of Medicine and Clinical Science, Graduate School of Pharmaceutical Sciences, Mukogawa Women’s University) ,  Futawaka Kumi (Department of Medicine and Clinical Science, Graduate School of Pharmaceutical Sciences, Mukogawa Women’s University) ,  Matsushita Midori (Department of Medicine and Clinical Science, Graduate School of Pharmaceutical Sciences, Mukogawa Women’s University) ,  Hatai Mayuko (Department of Medicine and Clinical Science, Graduate School of Pharmaceutical Sciences, Mukogawa Women’s University) ,  Yoshikawa Noriko (Department of Medicine and Clinical Science, Graduate School of Pharmaceutical Sciences, Mukogawa Women’s University) ,  Nakamura Kazuki (Department of Medicine and Clinical Science, Graduate School of Pharmaceutical Sciences, Mukogawa Women’s University) ,  Tagami Tetsuya (Division of Endocrinology, Metabolism and Hypertension, Clinical Research Institute, Kyoto Medical Center, National Hospital Organization) ,  Moriyama Kenji (Department of Medicine and Clinical Science, Graduate School of Pharmaceutical Sciences, Mukogawa Women’s University) ,  Moriyama Kenji (Division of Endocrinology, Metabolism and Hypertension, Clinical Research Institute, Kyoto Medical Center, National Hospital Organization)
資料名： Biological and Pharmaceutical Bulletin (Web)  (Biological and Pharmaceutical Bulletin (Web))
巻： 41  号： 3  ページ： 383-393(J-STAGE)  発行年： 2018年 
JST資料番号： U1402A  ISSN： 1347-5215  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： タバコの煙は4800を超える化合物を含み,少なくとも200の...

シソーラス用語： ヒト ,...
準シソーラス用語： 共役因子 ,...

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著者キーワード (6件)： signal transduction ,  thyroid hormone receptor ,  endocrine disruptor ,  signal transduction ,  thyroid hormone receptor ,  endocrine disruptor

分類 (1件)： 有機化合物の毒性  (GZ02030Y)

引用文献 (61件)：

• 1) Hoffmann D, Hoffmann I, El-Bayoumy K. The less harmful cigarette: a controversial issue. A tribute to Ernst L. Wynder. Chem. Res. Toxicol., 14, 767-790 (2001).
• 2) Aoshiba K, Nagai A. Oxidative stress, cell death, and other damage to alveolar epithelial cells induced by cigarette smoke. Tob. Induc. Dis., 1, 219-226 (2003).
• 3) Fearon IM, Faux SP. Oxidative stress and cardiovascular disease: Novel tools give (free) radical insight. J. Mol. Cell. Cardiol., 47, 372-381 (2009).
• 4) Tuder RM, Petrache I. Pathogenesis of chronic obstructive pulmonary disease. J. Clin. Invest., 122, 2749-2755 (2012).
• 5) Takahashi Y, Horiyama S, Honda C, Suwa K, Nakamura K, Kunitomo M, Shimma S, Toyoda M, Sato H, Shizuma M, Takayama M. A chemical approach to searching for bioactive ingredients in cigarette smoke. Chem. Pharm. Bull., 61, 85-89 (2013).

タイトルに関連する用語 (6件)： タバコ煙 ,  抽出物 ,  甲状腺ホルモン ,  受容体 ,  転写活性 ,  撹乱