文献

J-GLOBAL ID：201802281980720109   整理番号：18A0827084

HDAC阻害剤,SAHAはDSS誘発大腸炎において炎症性サイトカインおよびケモカインを抑制することにより結腸炎症を予防する

The HDAC Inhibitor, SAHA, Prevents Colonic Inflammation by Suppressing Pro-inflammatory Cytokines and Chemokines in DSS-induced Colitis

著者 (12件)： Ali Mohmand Noor (Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki) ,  Ali Mohmand Noor (Laboratory of Veterinary Pathology, Department of Veterinary, Faculty of Agriculture, University of Miyazaki) ,  Choijookhuu Narantsog (Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki) ,  Takagi Hideaki (Division of Immunology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki) ,  Srisowanna Naparee (Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki) ,  Nguyen Nhat Huynh Mai (Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki) ,  Yamaguchi Yuya (Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki) ,  Synn Oo Phyu (Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki) ,  Tin Htwe Kyaw Myat (Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki) ,  Sato Katsuaki (Division of Immunology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki) ,  Yamaguchi Ryoji (Laboratory of Veterinary Pathology, Department of Veterinary, Faculty of Agriculture, University of Miyazaki) ,  Hishikawa Yoshitaka (Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki)
資料名： Acta Histochemica et Cytochemica (Web)  (Acta Histochemica et Cytochemica (Web))
巻： 51  号： 1  ページ： 33-40(J-STAGE)  発行年： 2018年 
JST資料番号： U0129A  ISSN： 1347-5800  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 炎症性腸疾患(IBD)は,免疫系の機能不全および遺伝的および...

シソーラス用語： *炎症 ,...
準シソーラス用語： CCL2 ,...

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著者キーワード (4件)： 炎症性腸疾患 ,  ヒストンデアセチラーゼ阻害剤 ,  デキストラン硫酸ナトリウム ,  炎症性サイトカインとケモカイン

分類 (3件)： 消化器の基礎医学  (GH01020E) ,  消炎薬の基礎研究  (GW15010T) ,  腸  (EJ06040N)

物質索引 (1件)： SAHA

引用文献 (30件)：

• 1 Arimura, K., Takagi, H., Uto, T., Fukaya, T., Nakamura, T., Choijookhuu, N., Hishikawa, Y., Yamashita, Y. and Sato, K. (2017) Crucial role of plasmacytoid dendritic cells in the development of acute colitis through the regulation of intestinal inflammation. Mucosal Immunol. 10; 957-970.
• 2 Banks, C., Bateman, A., Payne, R., Johnson, P. and Sheron, N. (2003) Chemokine expression in IBD. Mucosal chemokine expression is unselectively increased in both ulcerative colitis and Crohn’s disease. J. Pathol. 199; 28-35.
• 3 Batmunkh, B., Choijookhuu, N., Srisowanna, N., Byambatsogt, U., Synn Oo, P., Noor Ali, M., Yamaguchi, Y. and Hishikawa, Y. (2017) Estrogen accelerates cell proliferation through estrogen receptor alpha during rat liver regeneration after partial hepatectomy. Acta Histochem. Cytochem. 50; 39-48.
• 4 Bode, K. A., Schroder, K., Hume, D. A., Ravasi, T., Heeg, K., Sweet, M. J. and Dalpke, A. H. (2007) Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. Immunology 122; 596-606.
• 5 Chun, E., Lavoie, S., Michaud, M., Gallini, C. A., Kim, J., Soucy, G., Odze, R., Glickman, J. N. and Garrett, W. S. (2015) CCL2 promotes colorectal carcinogenesis by enhancing poly­morphonuclear myeloid-derived suppressor cell population and function. Cell Rep. 12; 244-257.

タイトルに関連する用語 (9件)： HDAC阻害剤 ,  SAHA ,  DSS ,  誘発 ,  大腸炎 ,  炎症性サイトカイン ,  ケモカイン ,  結腸炎 ,  予防