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J-GLOBAL ID：201902244485000112   整理番号：19A0492999

出生時のカドミウムとサイズへの出生前曝露の臨界窓【JST・京大機械翻訳】

Critical Windows of Prenatal Exposure to Cadmium and Size at Birth

著者 (34件)： Cheng Lu (Key Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Cheng Lu (State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Zhang Bin (Key Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Zhang Bin (State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Zhang Bin (Women and Children Medical and Healthcare Center of Wuhan, Wuhan 430000, Hubei, China) ,  Zheng Tongzhang (Department of Epidemiology, Brown University, Providence, RI 02912, USA) ,  Hu Jie (Key Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Hu Jie (State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Zhou Aifen (Women and Children Medical and Healthcare Center of Wuhan, Wuhan 430000, Hubei, China) ,  Bassig Bryan A. (Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT 06520, USA) ,  Xia Wei (Key Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Xia Wei (State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Savitz David A. (Department of Epidemiology, Brown University, Providence, RI 02912, USA) ,  Buka Stephen (Department of Epidemiology, Brown University, Providence, RI 02912, USA) ,  Xiong Chao (Women and Children Medical and Healthcare Center of Wuhan, Wuhan 430000, Hubei, China) ,  Braun Joseph M. (Department of Epidemiology, Brown University, Providence, RI 02912, USA) ,  Zhang Yaqi (Women and Children Medical and Healthcare Center of Wuhan, Wuhan 430000, Hubei, China) ,  Zhou Yanqiu (Key Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Zhou Yanqiu (State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Pan Xinyun (Key Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Pan Xinyun (State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Wu Chuansha (Key Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Wu Chuansha (State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Wang Youjie (Key Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Wang Youjie (State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Qian Zhengmin (Department of Epidemiology, College for Public Health and Social Justice, Saint Louis University, Saint Louis, MO 63103, USA) ,  Yang Aimin (College of Earth and Environmental Science, Lanzhou University, Lanzhou 730000, Gansu, China) ,  Romano Megan E. (Department of Epidemiology, Brown University, Providence, RI 02912, USA) ,  Shi Kunchong (Department of Epidemiology, Brown University, Providence, RI 02912, USA) ,  Xu Shunqing (Key Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Xu Shunqing (State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Li Yuanyuan (Key Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Li Yuanyuan (State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China) ,  Li Yuanyuan (Department of Epidemiology, Brown University, Providence, RI 02912, USA)
資料名： International Journal of Environmental Research and Public Health (Web)  (International Journal of Environmental Research and Public Health (Web))
巻： 14  号： 1  ページ： 58  発行年： 2017年 
JST資料番号： U7208A  ISSN： 1660-4601  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： スイス (CHE)  言語： 英語 (EN)

抄録/ポイント： 出生前カドミウム(Cd)曝露は有害な出生結果と関連しているが,以前の研究の知見は矛盾している。著者らは,中国,武漢の282人の女性から,13,24,および35週齢の尿試料中のCd濃度を測定した。一般化された推定方程式モデルを用いて,各妊娠期における母親のクレアチニン調整尿中Cd濃度と出生時サイズの間の関連性を評価した。有意な逆相関が,第1の妊娠中に測定されたより高い母親のCdレベルと少女における出生サイズの間で観察された。第1の3半期からのCd(μg/gクレアチニン)レベルにおける各ログ単位増加に対して,116.99g(95%信頼区間(CI):-208.87,-25.11g)による出生体重の減少があった。第1および第2期からのCdレベルは,少女におけるポンデラル指数と有意に関連していた。三半期特異的影響の共同推定は,ポンデラル指数(pint=0.02)に対するCdレベルとの関連が,三半期間で有意に異なり,出生時体重に対する妊娠期の影響に対する差は,少女においてわずかに有意であることを示唆した。有意な関連性は,男児におけるすべての妊娠者と出生サイズからのCdレベルの間で観察されなかった。妊娠初期の母親のCd曝露は,胎児の成長遅延に大きな影響を及ぼす可能性がある。Copyright 2019 The Author(s) All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 妊娠期 ,  女性 ,  胎児 ,  妊娠初期 ,  *カドミウム ,  信頼区間 ,  妊娠 ,  疫学 ,  ラクタム
準シソーラス用語： 出生体重 ,  少女 ,  逆相関 ,  武漢市 ,  胎児期曝露 ,  *出生 , 【Automatic Indexing@JST】

著者キーワード (5件)： カドミウム ,  出生体重 ,  胎児曝露 ,  臨界窓 ,  疫学

分類 (3件)： 人間に対する影響  (EE05050C) ,  公衆衛生  (GB02000X) ,  その他の汚染原因物質  (SB05040W)

物質索引 (1件)： クレアチニン

引用文献 (33件)：

• Satarug, S.; Garrett, S.H.; Sens, M.A.; Sens, D.A. Cadmium, environmental exposure, and health outcomes. Environ. Health Perspect. 2010, 118, 182-190.
• Adams, S.V.; Quraishi, S.M.; Shafer, M.M.; Passarelli, M.N.; Freney, E.P.; Chlebowski, R.T.; Luo, J.; Meliker, J.R.; Mu, L.; Neuhouser, M.L. Dietary cadmium exposure and risk of breast, endometrial, and ovarian cancer in the women′s health initiative. Environ. Health Perspect. 2014, 122, 594-600.
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• Tellez-Plaza, M.; Navas-Acien, A.; Menke, A.; Crainiceanu, C.M.; Pastor-Barriuso, R.; Guallar, E. Cadmium exposure and all-cause and cardiovascular mortality in the us general population. Environ. Health Perspect. 2012, 120, 1017-1022.
• World Health Organization. Arsenic, Metals, Fibres, and Dusts. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans; World Health Organization: Geneva, Switzerland, 2012.

タイトルに関連する用語 (6件)： 出生 ,  カドミウム ,  サイズ ,  出生前曝露 ,  臨界 ,  窓