研究キーワード (5件):
Retinal development
, Photoreceptor cells
, Unfolded protein response
, ER stress
, Retinal degeneration
論文 (25件):
Hung-Ju Chiang, Yuko Nishiwaki, Wei-Chieh Chiang, Ichiro Masai. Male germ cell-associated kinase (MAK) is required for axoneme formation during ciliogenesis in zebrafish photoreceptors. Disease Models & Mechanisms. 2023
Kyle Kim, Lance A. Safarta, Wei-Chieh J. Chiang, Judith A. Coppinger, Eun-Jin Lee, Jonathan H. Lin. Network biology analysis of P23H rhodopsin interactome identifies protein and mRNA quality control mechanisms. Scientific Reports. 2022
Heike Kroeger, Julia M. D. Grandjean, Wei-Chieh Jerry Chiang, Daphne D. Bindels, Rebecca Mastey, Jennifer Okalova, Amanda Nguyen, Evan T. Powers, Jeffery W. Kelly, Neil J. Grimsey, et al. ATF6 is essential for human cone photoreceptor development. Proceedings of the National Academy of Sciences. 2021. 118. 39
Eun-Jin Lee, Wei-Chieh Jerry Chiang, Heike Kroeger, Chloe Xiaoke Bi, Daniel L. Chao, Dorota Skowronska-Krawczyk, Rebecca R. Mastey, Stephen H Tsang, Leon Chea, Kyle Kim, et al. Multiexon deletion alleles of ATF6 linked to achromatopsia. JCI Insight. 2020
Wei-Chieh Jerry Chiang, Heike Kroeger, Lulu Chea, Jonathan H. Lin. Pathomechanisms of ATF6-Associated Cone Photoreceptor Diseases. Retinal Degenerative Diseases. 2019
Wei-Chieh Chiang, Priscilla Chan, Susanne Kohl, Aioy Vincent, Anna Skorczyk-Werner, Maciej Robert Krawczynski, Stephen H. Tsang, Elise Heon, Bernd Wissinger, Jonathan H. Lin. Functional Diversity of Human ATF6 Mutations Associated with Achromatopsia. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2016. 57. 12
Heike Kroeger, Wei-Chieh Chiang, R. Luke Wiseman, Jonathan H. Lin. "ATF6 Promotes Early Stem Cell Development". FASEB JOURNAL. 2016. 30
Wei-Chieh Chiang, Priscilla Chan, Jonathan H. Lin. Functional Diversity of Novel Disease Mutations in the Unfolded Protein Response regulator, ATF6. FASEB JOURNAL. 2016. 30
Unfolded Protein Response Regulator, ATF6, is Essential for Stress Survival in Cone Photoreceptors
(ARVO2019 2019)
Mutations in the Unfolded Protein Response Regulator Atf6 Cause the Cone Dysfunction Disorder Achromatopsia
(Pathology Research Lecture Series (PRLS), University of California, San Diego 2015)
Endoplasmic Reticulum-Associated Degradation (ERAD) of Misfolded Rhodopsin in Retinal Degeneration
(Cellular and Molecular Medicine (CMM) Symposium, University of California, San Diego 2014)
Chemical-genetic activation of the Unfolded Protein Response reduces protein misfolding
(Pathology Research Lecture Series (PRLS), University of California, San Diego 2010)
Chemical-genetic activation of the Unfolded Protein Response reduces protein misfolding
(Federation of American Societies for Experimental Biology (FASEB) conference 2010)
- 2008 University of California, San Diego Chemistry and Biochemistry Ph.D.
- 2007 San Diego State University Chemistry M.A.
- 2001 National Taiwan University Chemistry B.S.
学位 (1件):
Ph.D. (University of California, San Diego)
経歴 (4件):
2019 - 現在 Okinawa Institute of Science and Technology Graduate University Developmental Neurobiology Unit Staff Scientist
2018 - 2019 University of California, San Diego Pathology Associate Project Scientist
2014 - 2018 VA San Diego Health Care System Research Biologist
2008 - 2014 University of California, San Diego Pathology Postdoctoral Research Fellow
受賞 (9件):
2019 - The Association for Research in Vision and Ophthalmology ARVO 2019 Travel Award
2018 - American Society for Investigative Pathology American Society for Investigative Pathology Trainee Travel Award
2018 - BrightFocus Foundation Travel Award BrightFocus Foundation Travel Award for XVIIIth International Symposium on Retinal Degenerations
2014 - NEI Travel Award for XVIth International Symposium on Retinal Degenerations
2014 - American Society for Investigative Pathology American Society for Investigative Pathology A. D. Sobel - ASIP Education Fund Scholar Awards
2010 - American Society for Investigative Pathology Young Pathologist Fellowship
2009 - Fight-For-Sight Fight-For-Sight Postdoctoral Fellowship Unfolded Protein Response Signaling in Rhodopsin Protein Processing and Stability
2005 - California Metabolic Research Foundation Arne N. Wick Predoctoral Research Fellowship
2003 - Graduate Division at San Diego State University Research fellowship of Shared Visions Fund
全件表示
所属学会 (4件):
International Zebrafish Society
, American Society for Cell Biology
, The Association for Research in Vision and Ophthalmology
, American Society for Investigative Pathology