文献

J-GLOBAL ID：202002217752778689   整理番号：20A1419964

肝細胞癌へのホウ素中性子捕獲療法のための10BSH封入水中油中水型エマルジョンの動脈内注入による単回投与毒性試験【JST・京大機械翻訳】

Single-dose toxicity study by intra-arterial injection of ¹⁰BSH entrapped water-in-oil-in-water emulsion for boron neutron capture therapy to hepatocellular carcinoma

著者 (34件)： Yanagie Hironobu (Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan) ,  Yanagie Hironobu (Cooperative Unit of Medicine & Engineering, The University of Tokyo Hospital, Tokyo, 113-8655, Japan) ,  Yanagie Hironobu (Research Institute of Healthy Living, Niigata University of Pharmacy & Applied Life Sciences, Niigata, 956-8603, Japan) ,  Yanagawa Masashi (Veterinary Medical Center, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, 080-8555, Japan) ,  Higuchi Tsuyoshi (Department of Pharmacology, Kumamoto Institute Branch, LSI Medience Ltd. Co., Kumamoto, 869-0425, Japan) ,  Mizumachi Ryouji (Department of Pharmacology, Kumamoto Institute Branch, LSI Medience Ltd. Co., Kumamoto, 869-0425, Japan) ,  Fujihara Mitsuteru (SPG Techno Ltd. Co., Miyazaki, 880-0303, Japan) ,  Morishita Yasuyuki (Department of Human & Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan) ,  Sakurai Yuriko (Cooperative Unit of Medicine & Engineering, The University of Tokyo Hospital, Tokyo, 113-8655, Japan) ,  Sakurai Yuriko (Research Institute of Healthy Living, Niigata University of Pharmacy & Applied Life Sciences, Niigata, 956-8603, Japan) ,  Mouri Kikue (Cooperative Unit of Medicine & Engineering, The University of Tokyo Hospital, Tokyo, 113-8655, Japan) ,  Mouri Kikue (Research Institute of Healthy Living, Niigata University of Pharmacy & Applied Life Sciences, Niigata, 956-8603, Japan) ,  Dewi Novriana (Cooperative Unit of Medicine & Engineering, The University of Tokyo Hospital, Tokyo, 113-8655, Japan) ,  Dewi Novriana (Research Institute of Healthy Living, Niigata University of Pharmacy & Applied Life Sciences, Niigata, 956-8603, Japan) ,  Nonaka Yasumasa (Department of Surgery, Keiai-kai Hoyo Hospital, Iwate, 028-3111, Japan) ,  Shinohara Atsuko (Department of Humanities, The Graduate School of Seisen University, Tokyo, 141-8642, Japan) ,  Shinohara Atsuko (Department of Hygiene, Faculty of Medicine, Juntendo University, Tokyo, 113-8421, Japan) ,  Matsukawa Takehisa (Department of Hygiene, Faculty of Medicine, Juntendo University, Tokyo, 113-8421, Japan) ,  Kubota Ayano (Department of Hygiene, Faculty of Medicine, Juntendo University, Tokyo, 113-8421, Japan) ,  Yokoyama Kazuhito (Department of Hygiene, Faculty of Medicine, Juntendo University, Tokyo, 113-8421, Japan) ,  Suzuki Minoru (Kyoto Univ Institute for Integrated Radiation & Nuclear Science, Osaka, 590-0494, Japan) ,  Masunaga Shin-ichiro (Kyoto Univ Institute for Integrated Radiation & Nuclear Science, Osaka, 590-0494, Japan) ,  Sakurai Yohinori (Kyoto Univ Institute for Integrated Radiation & Nuclear Science, Osaka, 590-0494, Japan) ,  Tanaka Hiroki (Kyoto Univ Institute for Integrated Radiation & Nuclear Science, Osaka, 590-0494, Japan) ,  Ono Koji (Kansai BNCT Medical Center, Osaka Medical College, Osaka, 569-8686, Japan) ,  Yamauchi Haruo (Cooperative Unit of Medicine & Engineering, The University of Tokyo Hospital, Tokyo, 113-8655, Japan) ,  Yamauchi Haruo (Department of Cardiac Surgery, The University of Tokyo Hospital, Tokyo, 113-8655, Japan) ,  Ono Minoru (Cooperative Unit of Medicine & Engineering, The University of Tokyo Hospital, Tokyo, 113-8655, Japan) ,  Ono Minoru (Department of Cardiac Surgery, The University of Tokyo Hospital, Tokyo, 113-8655, Japan) ,  Nakajima Jun (Cooperative Unit of Medicine & Engineering, The University of Tokyo Hospital, Tokyo, 113-8655, Japan) ,  Nakajima Jun (Department of Pulmonary Surgery, The University of Tokyo Hospital, Tokyo, 113-8655, Japan) ,  Higashi Shushi (Department of Surgery, Kojin-kai Medicalcity East Hospital, Miyazaki, 885-0035, Japan) ,  Takahashi Hiroyuki (Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan) ,  Takahashi Hiroyuki (Cooperative Unit of Medicine & Engineering, The University of Tokyo Hospital, Tokyo, 113-8655, Japan)
資料名： Applied Radiation and Isotopes  (Applied Radiation and Isotopes)
巻： 163  ページ： Null  発行年： 2020年 
JST資料番号： C0201A  ISSN： 0969-8043  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： イギリス (GBR)  言語： 英語 (EN)

抄録/ポイント： 肝細胞癌(HCC)治療のための10B封入WOWエマルションとして適用するために,水中油中水(WOW)エマルションを調製するために,Shirasu多孔性ガラスMillipore膜を付着させることによる混合医療装置を開発した。10BSH封入WOWの動脈内注射による単回投与毒性試験をウサギとブタで行い,副作用は観察されなかった。HCCに対する学際的治療として10B化合物の更なる評価のための前臨床および臨床研究への進行を期待する。Copyright 2020 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 乳濁液 ,  動脈内投与 ,  副作用 ,  境界領域 ,  *肝細胞癌 ,  *単回投与 ,  *毒性試験
準シソーラス用語： ホウ素中性子捕獲療法 ,  O/W型 ,  W/O/Wエマルション ,  動脈内注入 ,  臨床研究 , 【Automatic Indexing@JST】

著者キーワード (5件)： BNCT ,  肝細胞癌 ,  WOWエマルション ,  混合医療装置 ,  動脈内注射

分類 (1件)： 腫ようの放射線療法  (GE03034K)

タイトルに関連する用語 (8件)： 肝細胞癌 ,  ホウ素中性子捕獲療法 ,  封入 ,  水中油中水型 ,  エマルジョン ,  動脈内注入 ,  単回投与 ,  毒性試験