文献

J-GLOBAL ID：202002266982025763   整理番号：20A2212129

RAS-RAF軸における発癌性変異はGREB1の発現を増加させ,結腸直腸癌の腫瘍増殖を引き起こす

Oncogenic mutation in RAS-RAF axis leads to increased expression of GREB1, resulting in tumor proliferation in colorectal cancer

著者 (16件)： Kochi Masatoshi (Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Hinoi Takao (Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Hinoi Takao (Department of Surgery, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan) ,  Hinoi Takao (Department of Clinical and Molecular Genetics, Hiroshima University Hospital, Hiroshima, Japan) ,  Niitsu Hiroaki (Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA) ,  Miguchi Masashi (Department of Gastroenterological, Breast and Transplant Surgery, Hiroshima Prefectural Hospital, Hiroshima, Japan) ,  Saito Yasufumi (Department of Surgery, Chugoku Rosai Hospital, Hiroshima, Japan) ,  Sada Haruki (Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Sada Haruki (Department of Surgery, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan) ,  Sentani Kazuhiro (Department of Molecular Pathology, Hiroshima University Institute of Biomedical and Health Sciences, Hiroshima, Japan) ,  Sakamoto Naoya (Department of Molecular Pathology, Hiroshima University Institute of Biomedical and Health Sciences, Hiroshima, Japan) ,  Oue Naohide (Department of Molecular Pathology, Hiroshima University Institute of Biomedical and Health Sciences, Hiroshima, Japan) ,  Tashiro Hirotaka (Department of Surgery, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan) ,  Sotomaru Yusuke (Natural Science Center for Basic Research and Development, Hiroshima University, Hiroshima, Japan) ,  Yasui Wataru (Department of Molecular Pathology, Hiroshima University Institute of Biomedical and Health Sciences, Hiroshima, Japan) ,  Ohdan Hideki (Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan)
資料名： Cancer Science (Web)  (Cancer Science (Web))
巻： 111  号： 10  ページ： 3540-3549  発行年： 2020年 
JST資料番号： U0505A  ISSN： 1349-7006  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： BRAF^V600E変異は,ヒト結腸直腸...

シソーラス用語： マウス ,...
準シソーラス用語： BRAF遺伝子 ,...

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著者キーワード (5件)： BRAF変異 ,  結腸直腸癌 ,  ER ,  GREB1 ,  マウスモデル

分類 (2件)： 発癌機序・因子  (GE02020C) ,  遺伝子発現  (EC02040Q)

タイトルに関連する用語 (7件)： Ras ,  Raf ,  発癌性 ,  変異 ,  発現 ,  結腸直腸癌 ,  腫瘍増殖