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J-GLOBAL ID：202002274298077173   整理番号：20A1255604

加齢黄斑変性患者由来のヒト人工多能性幹細胞株,BRCI004-Aの生成【JST・京大機械翻訳】

Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration

著者 (27件)： Kamata Kazuma (iPSC-based Drug discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan) ,  Otsuka Yuki (iPSC-based Drug discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan) ,  Otsuka Yuki (Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan) ,  Otsuka Yuki (Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan) ,  Imamura Keiko (iPSC-based Drug discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan) ,  Imamura Keiko (Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan) ,  Imamura Keiko (Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), Kyoto, 606-8507, Japan) ,  Oishi Akio (Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan) ,  Kondo Takayuki (iPSC-based Drug discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan) ,  Kondo Takayuki (Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan) ,  Kondo Takayuki (Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), Kyoto, 606-8507, Japan) ,  Suga Mika (iPSC-based Drug discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan) ,  Suga Mika (Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan) ,  Shibukawa Ran (iPSC-based Drug discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan) ,  Shibukawa Ran (Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan) ,  Okanishi Yasue (iPSC-based Drug discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan) ,  Sagara Yukako (iPSC-based Drug discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan) ,  Tsukita Kayko (iPSC-based Drug discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan) ,  Tsukita Kayko (Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan) ,  Yasukawa Tsutomu (Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan) ,  Usui Hideaki (Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan) ,  Muguruma Keiko (Laboratory for Cell Asymmetry, RIKEN Center for Developmental Biology, Kobe, 650-0047, Japan) ,  Muguruma Keiko (Department of iPS Cell Applied Medicine, Graduate School of Medicine, Kansai Medical University, Hirakata, 573-1010, Japan) ,  Tsujikawa Akitaka (Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan) ,  Inoue Haruhisa (iPSC-based Drug discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan) ,  Inoue Haruhisa (Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan) ,  Inoue Haruhisa (Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan)
資料名： Stem Cell Research (Web)  (Stem Cell Research (Web))
巻： 45  ページ： Null  発行年： 2020年 
JST資料番号： U7041A  ISSN： 1873-5061  資料種別： 逐次刊行物 (A)
記事区分： 短報  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 加齢黄斑変性(AMD)は遅発性進行性失明疾患である。著者らは,AMD患者からヒト誘発多能性幹細胞(iPSC)を確立した。発生したiPSC系統は,in vitroで多能性マーカーと3-胚芽層分化能を示した。このiPSC系統は,AMDに対する病理学的機構と創薬の解明に有用である。Copyright 2020 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： ヒト ,  分化 ,  汎用性 ,  胚芽 ,  in vitro実験 ,  *多能性幹細胞 ,  *iPS細胞
準シソーラス用語： *老人性黄斑変性 ,  創薬 ,  後期発症 , 【Automatic Indexing@JST】

分類 (1件)： 発生と分化  (EJ16020W)

タイトルに関連する用語 (5件)： 加齢黄斑変性 ,  患者 ,  ヒト ,  人工多能性幹細胞 ,  株