文献

J-GLOBAL ID：202102244192047711   整理番号：21A0289067

TRAF6と腫瘍の関係【JST・京大機械翻訳】

The relationship between TRAF6 and tumors

著者 (35件)： Li Jiaoduan (Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China) ,  Li Jiaoduan (National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China) ,  Li Jiaoduan (Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Changsha, China) ,  Li Jiaoduan (Hunan Engineering Research Center of Skin Health and Disease, Xiangya Hospital, Changsha, China) ,  Li Jiaoduan (Xiangya Clinical Research Center for Cancer Immunotherapy, Central South University, Changsha, China) ,  Liu Nian (Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China) ,  Liu Nian (National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China) ,  Liu Nian (Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Changsha, China) ,  Liu Nian (Hunan Engineering Research Center of Skin Health and Disease, Xiangya Hospital, Changsha, China) ,  Liu Nian (Xiangya Clinical Research Center for Cancer Immunotherapy, Central South University, Changsha, China) ,  Tang Ling (Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China) ,  Tang Ling (National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China) ,  Tang Ling (Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Changsha, China) ,  Tang Ling (Hunan Engineering Research Center of Skin Health and Disease, Xiangya Hospital, Changsha, China) ,  Tang Ling (Xiangya Clinical Research Center for Cancer Immunotherapy, Central South University, Changsha, China) ,  Yan Bei (Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China) ,  Yan Bei (National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China) ,  Yan Bei (Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Changsha, China) ,  Yan Bei (Hunan Engineering Research Center of Skin Health and Disease, Xiangya Hospital, Changsha, China) ,  Yan Bei (Xiangya Clinical Research Center for Cancer Immunotherapy, Central South University, Changsha, China) ,  Chen Xiang (Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China) ,  Chen Xiang (National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China) ,  Chen Xiang (Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Changsha, China) ,  Chen Xiang (Hunan Engineering Research Center of Skin Health and Disease, Xiangya Hospital, Changsha, China) ,  Chen Xiang (Xiangya Clinical Research Center for Cancer Immunotherapy, Central South University, Changsha, China) ,  Zhang Jianglin (Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China) ,  Zhang Jianglin (National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China) ,  Zhang Jianglin (Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Changsha, China) ,  Zhang Jianglin (Hunan Engineering Research Center of Skin Health and Disease, Xiangya Hospital, Changsha, China) ,  Zhang Jianglin (Xiangya Clinical Research Center for Cancer Immunotherapy, Central South University, Changsha, China) ,  Peng Cong (Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China) ,  Peng Cong (National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China) ,  Peng Cong (Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Changsha, China) ,  Peng Cong (Hunan Engineering Research Center of Skin Health and Disease, Xiangya Hospital, Changsha, China) ,  Peng Cong (Xiangya Clinical Research Center for Cancer Immunotherapy, Central South University, Changsha, China)
資料名： Cancer Cell International (Web)  (Cancer Cell International (Web))
巻： 20  号： 1  ページ： 1-12  発行年： 2020年 
JST資料番号： U7315A  ISSN： 1475-2867  資料種別： 逐次刊行物 (A)
記事区分： 文献レビュー  発行国： イギリス (GBR)  言語： 英語 (EN)

抄録/ポイント： 腫瘍壊死因子受容体(TNFR)関連因子(TRAF)は,腫瘍壊死因子スーパーファミリー(TNFSF)およびToll様/インターロイキン-1受容体(TLR/ILR)スーパーファミリーにおける重要なリンカー分子である。7つのメンバー:TRAF1-TRAF7がそれらのメンバーの間にあり,腫瘍壊死因子受容体関連因子6(TRAF6)は,腫瘍形成と発生に関連する様々な腫瘍でアップレギュレートされる。TRAF6と異なるタイプの腫瘍の間の関係の綿密な研究で,TRAF6は腫瘍形成,腫瘍発生,浸潤,および種々のシグナル伝達経路を介した転移に関与する発癌特性を有し,従ってTRAF6の標的化は腫瘍治療のための新規戦略を提供する。本レビューでは,TRAF6および腫瘍に関する現在の研究と組み合わせた腫瘍形成および腫瘍発生におけるTRAF6の役割をまとめ,分析した。Copyright 2021 The Author(s) All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 浸潤 ,  *腫瘍 ,  受容体 ,  発癌 ,  TNF【壊死因子】 ,  ターゲティング ,  インターロイキン1 ,  腫瘤形成
準シソーラス用語： *TRAF ,  腫瘍治療 , 【Automatic Indexing@JST】

著者キーワード (5件)： TRAF6 ,  腫瘍形成 ,  E3ユビキチンリガーゼ ,  AP-1 ,  NF-κB

分類 (1件)： 細胞生理一般  (EF02010S)

引用文献 (118件)：

• Cell; A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor; M Rothe, SC Wong, WJ Henzel, DV Goeddel; 78; 4; 1994; 681-692; citation_id=CR1
• J Exp Med; Tumor necrosis factor receptor-associated factor 6 (TRAF6) stimulates extracellular signal-regulated kinase (ERK) activity in CD40 signaling along a ras-independent pathway; M Kashiwada, Y Shirakata, JI Inoue, H Nakano, K Okazaki, K Okumura, T Yamamoto, H Nagaoka, T Takemori; 187; 2; 1998; 237-244; citation_id=CR2
• Oncogene; Tumor necrosis factor receptor-associated factors (TRAFs); JR Bradley, JS Pober; 20; 44; 2001; 6482-6491; citation_id=CR3
• J Invest Dermatol; TRAF1 is critical for DMBA/solar UVR-induced skin carcinogenesis; H Yamamoto, J Ryu, E Min, N Oi, R Bai, TA Zykova, DH Yu, K Moriyama, AM Bode, Z Dong; 137; 6; 2017; 1322-1332; citation_id=CR4
• Cancer Res; TRAF1 is critical for regulating the BRAF/MEK/ERK pathway in non-small cell lung carcinogenesis; Q Wang, G Gao, T Zhang, K Yao, H Chen, MH Park, H Yamamoto, K Wang, W Ma, M Malakhova; 78; 14; 2018; 3982-3994; citation_id=CR5

タイトルに関連する用語 (2件)： TRAF6 ,  腫瘍