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J-GLOBAL ID：202102260108991715   整理番号：21A0037540

ABC輸送体の新しい分類に対する構造的および機能的多様性コール【JST・京大機械翻訳】

Structural and functional diversity calls for a new classification of ABC transporters

著者 (46件)： Thomas Christoph (Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Germany) ,  Aller Stephen G. (Department of Pharmacology and Toxicology, University of Alabama at Birmingham, AL, USA) ,  Beis Konstantinos (Department of Life Sciences, Imperial College London, London South Kensington, UK) ,  Beis Konstantinos (Rutherford Appleton Laboratory, Research Complex at Harwell, Didcot, UK) ,  Carpenter Elisabeth P. (Structural Genomics Consortium, University of Oxford, UK) ,  Chang Geoffrey (Skaggs School of Pharmacy and Pharmaceutical Sciences and Department of Pharmacology, School of Medicine, University of California, San Diego, La Jolla, CA, USA) ,  Chen Lei (State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Peking University, Beijing, China) ,  Chen Lei (Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China) ,  Dassa Elie (Institut Pasteur, Paris Cedex 15, France) ,  Dean Michael (Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Gaithersburg, MD, USA) ,  Duong Van Hoa Franck (Department of Biochemistry and Molecular Biology, Faculty of Medicine, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada) ,  Ekiert Damian (Department of Cell Biology and Department of Microbiology, New York University School of Medicine, NY, USA) ,  Ford Robert (Faculty of Biology, Medicine and Health, The University of Manchester, UK) ,  Gaudet Rachelle (Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA) ,  Gong Xin (Department of Biology, Southern University of Science and Technology, Shenzhen, China) ,  Holland I. Barry (Institute for Integrative Biology of the Cell (I2BC), Universite Paris-Sud, Orsay, France) ,  Huang Yihua (National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China) ,  Kahne Daniel K. (Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA) ,  Kato Hiroaki (Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Japan) ,  Koronakis Vassilis (Department of Pathology, University of Cambridge, UK) ,  Koth Christopher M. (Structural Biology, Genentech Inc., South San Francisco, CA, USA) ,  Lee Youngsook (Division of Integrative Bioscience and Biotechnology, POSTECH, Pohang, Korea) ,  Lewinson Oded (Department of Biochemistry, The Bruce and Ruth Rappaport Faculty of Medicine, The Technion-Israel Institute of Technology, Haifa, Israel) ,  Lill Roland (Institut fuer Zytobiologie, Philipps-Universitaet Marburg, Germany) ,  Martinoia Enrico (Department of Plant and Microbial Biology, University Zurich, Switzerland) ,  Martinoia Enrico (International Research Centre for Environmental Membrane Biology, Foshan University, Foshan, China) ,  Murakami Satoshi (Department of Life Science, Tokyo Institute of Technology, Yokohama, Japan) ,  Pinkett Heather W. (Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA) ,  Poolman Bert (Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands) ,  Rosenbaum Daniel (Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA) ,  Sarkadi Balazs (Institute of Enzymology, Research Center for Natural Sciences (RCNS), Budapest, Hungary) ,  Schmitt Lutz (Institute of Biochemistry, Heinrich Heine University Duesseldorf, Duesseldorf, Germany) ,  Schneider Erwin (Department of Biology/Microbial Physiology, Humboldt-University of Berlin, Germany) ,  Shi Yigong (Institute of Biology, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, China) ,  Shyng Show-Ling (Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, OR, USA) ,  Slotboom Dirk J. (Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands) ,  Tajkhorshid Emad (Department of Biochemistry, Center for Biophysics and Quantitative Biology, NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, IL, USA) ,  Tieleman D. Peter (Department of Biological Sciences and Centre for Molecular Simulation, University of Calgary, AB, Canada) ,  Ueda Kazumitsu (Institute for Integrated Cell-Material Sciences (WPI-iCeMS), KUIAS, Kyoto University, Japan) ,  Varadi Andras (Institute of Enzymology, Research Center for Natural Sciences (RCNS), Budapest, Hungary) ,  Wen Po-Chao (Department of Biochemistry, Center for Biophysics and Quantitative Biology, NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, IL, USA) ,  Yan Nieng (Department of Molecular Biology, Princeton University, NJ, USA) ,  Zhang Peng (National Key Laboratory of Plant Molecular Genetics, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China) ,  Zheng Hongjin (Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA) ,  Zimmer Jochen (Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA, USA) ,  Tampe Robert (Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Germany)
資料名： FEBS Letters  (FEBS Letters)
巻： 594  号： 23  ページ： 3767-3775  発行年： 2020年 
JST資料番号： D0575A  ISSN： 0014-5793  資料種別： 逐次刊行物 (A)
記事区分： 文献レビュー  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： ATP結合カセット(ABC)輸送体スーパーファミリーのメンバーは,広範な化学的に多様な基質を移動する。ヌクレオチド結合ドメイン(NBD)におけるそれらのエポニムATP結合カセットは高度に保存されるが,転座経路を形成する膜貫通ドメイン(TMD)は,異なる折畳みとトポロジーを示し,進化時に,古代運動ドメインが様々な細胞過程を調整する異なる膜貫通機械的系と結合することを示唆した。近年,異なるTMD折畳みが多数のABC輸送体を分類するのに最も適していることが明らかになってきた。従って,TMDの構造相同性に基づく新しいABC輸送体分類を提案した。Copyright 2021 Wiley Publishing Japan K.K. All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 位相幾何学 ,  ATPアーゼ ,  基質 ,  ヌクレオチド ,  系統発生 ,  折畳み ,  結合部位 ,  膜タンパク質 ,  転座 ,  相同性 ,  *ABC輸送体
準シソーラス用語： *輸送体 ,  ATP結合カセット ,  ドメイン構造 ,  膜貫通領域 , 【Automatic Indexing@JST】

著者キーワード (10件)： ABCトランスポーター ,  ATPアーゼ ,  クライオ-EM ,  膜蛋白質 ,  分子機械 ,  系統発生 ,  一次活性輸送体 ,  配列アラインメント ,  構造生物学 ,  X線結晶学

分類 (1件)： 生物学的機能  (EB03040U)

タイトルに関連する用語 (4件)： ABC輸送体 ,  分類 ,  多様性 ,  コール