文献

J-GLOBAL ID：202202237266596977   整理番号：22A1029760

体重と摂食量の増加は,マウスにおいて食餌脂肪の増加と炭水化物または蛋白質増加に関連する【JST・京大機械翻訳】

Increased Variation in Body Weight and Food Intake Is Related to Increased Dietary Fat but Not Increased Carbohydrate or Protein in Mice

著者 (32件)： Wu Yingga (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Wu Yingga (University of Chinese Academy of Sciences, Beijing, China) ,  Wu Yingga (Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, United Kingdom) ,  Hu Sumei (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Hu Sumei (Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center of Food Additives, National Soybean Processing Industry Technology Innovation Center, Beijing, China) ,  Yang Dengbao (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Li Li (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Li Li (University of Chinese Academy of Sciences, Beijing, China) ,  Li Baoguo (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Li Baoguo (University of Chinese Academy of Sciences, Beijing, China) ,  Wang Lu (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Wang Lu (University of Chinese Academy of Sciences, Beijing, China) ,  Wang Lu (Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, United Kingdom) ,  Li Min (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Li Min (University of Chinese Academy of Sciences, Beijing, China) ,  Li Min (Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, United Kingdom) ,  Li Min (Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China) ,  Wang Guanlin (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Wang Guanlin (University of Chinese Academy of Sciences, Beijing, China) ,  Wang Guanlin (Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, United Kingdom) ,  Li Jianbo (University of Dali, Dali, China) ,  Xu Yanchao (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Zhang Xueying (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Zhang Xueying (University of Chinese Academy of Sciences, Beijing, China) ,  Zhang Xueying (Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, United Kingdom) ,  Zhang Xueying (Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China) ,  Niu Chaoqun (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Niu Chaoqun (Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China) ,  Speakman John R. (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) ,  Speakman John R. (Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, United Kingdom) ,  Speakman John R. (Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China) ,  Speakman John R. (CAS Center of Excellence in Animal Evolution and Genetics, Kunming, China)
資料名： Frontiers in Nutrition (Web)  (Frontiers in Nutrition (Web))
巻： 9  ページ： 835536  発行年： 2022年 
JST資料番号： U7088A  ISSN： 2296-861X  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： スイス (CHE)  言語： 英語 (EN)

抄録/ポイント： 種々の近交系マウス系統が代謝障害の研究に使用されている。近交系にもかかわらず,それらは食物摂取や体重のような多くの形質に対して大きな個体間変動を示す。しかし,異なるマウス菌株の体重と食物摂取における食事マクロ栄養素と個人間変動の間の関係はまだ不明である。異なる蛋白質,脂肪,および炭水化物含有量を有する24の異なる飼料に5つの異なるマウス菌株(C57BL/6,BALB/c,C3H,DBA/2,およびFVB)を曝露することによって,食事のマクロ栄養素含有量と食物摂取,体組成,およびグルコース耐性の変化の間の関連を調査した。食餌脂肪の増加のみを見出したが,蛋白質または炭水化物は,食品摂取と体重の両方の変化と有意な関連(陽性)を示した。体重と食物摂取の最も高い変動は,50%の食事脂肪で発生した。しかし,食事蛋白質,脂肪,または炭水化物レベルによる脂肪と痩せた質量の変化の間には,有意な関係はなかった。さらに,食餌性マクロ栄養素のどれも,C57BL/6マウスにおけるグルコース耐性能力の変化に有意な影響を及ぼさなかった。結論として,食物摂取と体重変化の変化は,食事脂肪レベルの上昇に伴って増加した。Copyright 2022 The Author(s) All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 実験動物 ,  *タンパク質 ,  *マウス ,  食事 ,  *摂食 ,  多量要素 ,  代謝異常 ,  *脂肪 ,  *体重 ,  耐糖性
準シソーラス用語： 近交系マウス ,  体重変化 ,  C57BL/6マウス ,  *食事性脂肪 ,  *食事摂取量 ,  近交系 , 【Automatic Indexing@JST】

著者キーワード (6件)： 蛋白質 ,  脂肪 ,  炭水化物 ,  マウス ,  歪 ,  変化

分類 (2件)： 代謝異常・栄養性疾患一般  (GD05010J) ,  動物の代謝と栄養一般  (EJ02031R)

引用文献 (39件)：

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• Schutz Y. Macronutrients and energy balance in obesity. Metabolism. (1995) 44:7-11. doi: 10.1016/0026-0495(95)90311-9
• Speakman JR. The roles of different macronutrients in regulation of appetite, energy intake and adiposity. Curr Opin Endocr Metabol Res. (2021) 22:100297. doi: 10.1016/j.coemr.2021.100297
• van Dam RM, Seidell JC. Carbohydrate intake and obesity. Eur J Clin Nutr. (2007) 61:S75-99. doi: 10.1038/sj.ejcn.1602939
• Willett WC. Dietary fat and obesity: an unconvincing relation. Am J Clin Nutr. (1998) 68:1149-50. doi: 10.1093/ajcn/68.6.1149

タイトルに関連する用語 (6件)： 体重 ,  摂食量 ,  マウス ,  食餌脂肪 ,  炭水化物 ,  蛋白質