Rchr
J-GLOBAL ID:200901000007031155
Update date: Jan. 16, 2025 Yamashita Satoshi
ヤマシタ サトシ | Yamashita Satoshi
Affiliation and department: Job title:
Professor
Homepage URL (1): https://www.acoffice.jp/mithp/KgApp?resId=S000123 Research field (5):
Analytical chemistry
, Genomics
, Molecular biology
, Applied biochemistry
, Tumor biology
Research keywords (6):
DNA methylation
, epigenome
, ゲノム
, cancer
, mutation
, 分析化学
Research theme for competitive and other funds (10): - 2021 - 2024 Synthetic lethality with gene silencing
- 2021 - 2024 Revealing specific local invasion mechanism in CNS using small cell lung cancer metastasis cell lines
- 2019 - 2022 Identification of individual carcinogenic factors by mutation signature analysis in normal human tissues
- 2016 - 2019 Quantification of ultra-rare somatic mutations using molecular barcode and risk assessment of cancer
- 2016 - 2018 enome-wide DNA methylation profiling identifies primary central nervous system lymphomas as a distinct entity from systemic diffuse large B-cell lymphomas
- 2011 - 2013 Molecular mechanisms for induction of DNA methylation by testosterone overdose in the rat prostate
- 2008 - 2010 Establishment of a transgenic rat model which develop tumors with high frequent aberrant DNA methylation
- 2005 - 2009 Identification of tumor suppressor genes in gastric cancers by genome-wide analysis of DNA methylation and its functional analysis
- 2003 - 2005 Scd2トランスジェニックラットの発がん感受性
- 2001 - 2002 大量・高速なマッピングシステムを目指した電極による遺伝子型決定法の開発
Show all
Papers (159): -
リュウ・ユユ, 竹内 千尋, 山下 聡, 牛島 俊和. 若年者エピゲノムの高可塑性 AYAがんの高悪性度の原因の可能性(High plasticity of the epigenome in youth: possible cause of aggressive AYA cancers). 日本癌学会総会記事. 2024. 83回. IS06-7
-
竹内 千尋, 山下 聡, リュウ・ユユ, 竹島 秀幸, 藤城 光弘, 牛島 俊和. DNAメチル化の加速とエピゲノム景観の変化を伴う腸上皮化生の前癌性(Precancerous nature of intestinal metaplasia with accelerated DNA methylation along with altered epigenomic landscape). 日本癌学会総会記事. 2024. 83回. YIA1-2
-
Yuta Yamamoto, Tatsuro Watanabe, Hiroshi Ureshino, Yuki Kurahashi, Yuki Fukuda-Kurahashi, Kazuharu Kamachi, Kazunori Kawasoe, Keisuke Kidoguchi, Satoshi Yamashita, Naoko Hattori, et al. DNA demethylating agents for chemoprevention of oncovirus-associated leukemogenesis. Leukemia. 2024
-
Yu-Yu Liu, Chihiro Takeuchi, Satoshi Yamashita, Toshikazu Ushijima. Abstract 7016: Plastic epigenome in youth: Insights from open chromatin in stem cells. Cancer Research. 2024. 84. 6_Supplement. 7016-7016
-
Akiko Sasaki, Hideyuki Takeshima, Satoshi Yamashita, Chikamasa Ichita, Jun Kawachi, Wataru Naito, Yui Ohashi, Chihiro Takeuchi, Masahide Fukuda, Yumi Furuichi, et al. Severe induction of aberrant DNA methylation by nodular gastritis in adults. Journal of gastroenterology. 2024
more... MISC (37): -
LIU Yuyu, 竹内千尋, 山下聡, 牛島俊和. 胃幹細胞における「ランダムな少数細胞でのオープンクロマチン領域」の加齢による消失と環境刺激への脆弱性の増加. 日本分子生物学会年会プログラム・要旨集(Web). 2024. 47th
-
Sho Tsuyuki, Hideyuki Takeshima, Yukinori Yamagata, Takayuki Ando, Satoshi Yamashita, Shin Maeda, Toshikazu Ushijima. Comparable somatic mutation profiles between gastric cancers with past H. pylori infection and current infection. CANCER SCIENCE. 2022. 113. 1661-1661
-
佐々木重嘉, 久米賢, 立石健祐, 中村大志, 井林賢志, 山岸夢希, 齊藤邦昭, 小林啓一, 松下裕子, 日比谷優子, et al. Paired mutational analysis in secondary nervous system lymphoma and PCNSL systemic relapse reveals driver mutation candidates in the central nervous system. 日本脳腫瘍学会学術集会プログラム・抄録集. 2022. 40th
-
Tatsuro Watanabe, Hiroshi Ureshino, Satoshi Yamashita, Toshikazu Ushijima, Seiji Okada, Eisaburo Sueoka, Shinya Kimura. DNA hypermethylation of THEMIS, a regulator of T-Cell Receptor signaling, in adult T-cell leukemia-lymphoma. CANCER SCIENCE. 2021. 112. 260-260
-
福田昌英, 九嶋亮治, 石垣宏仁, 佐々木亜希子, 水上一弘, 上尾哲也, 村上和成, 織田麻奈美, 織田麻奈美, 山下聡, et al. Fundic gland polyps and gastric-foveolar type neoplasm. 日本病理学会会誌. 2021. 110. 1. 174-174
more... Patents (10): Books (36): - エピゲノム異常
羊土社 2024
- バイオアナライザ・TapeStationとRIN値・DIN値
羊土社 2022
- エピジェネティックスな状態を知る〜がんとDNAメチル化を例に
羊土社 2022
- InfiniumによるDNAメチル化解析
羊土社 2017
- ハイエンド研究・分析装置への招待状(vol.2)次世代シークエンサー(第4回)NGSで解き明かすエピゲノム
2017
more... Education (4): - 1995 - 1998 The University of Tokyo Graduate School, Division of Engineering
- 1995 - 1998 The University of Tokyo The Graduate School of Engineering Department of Chemistry and Biotechnology
- 1990 - 1992 The University of Tokyo The Graduate School of Engineering
- 1986 - 1990 The University of Tokyo The Faculty of Engineering
Professional career (1): Work history (9): - 2022/04 - 現在 Maebashi Institute of Technology
- 2013/04 - 現在 Nagoya City University
- 2010/04 - 2022/03 国立研究開発法人 国立がん研究センター 研究所 エピゲノム解析分野 室長
- 2011/04 - 2014/03 独立行政法人国立環境研究所 大学等非常勤研究員
- 2007/04 - 2010/03 国立がんセンター 研究所 発がん研究部 室長
- 2006/04 - 2007/03 国立がんセンター 研究所 発がん研究部 主任研究員
- 1999/07 - 2006/03 国立がんセンター 研究所 発がん研究部 研究員
- 1998/04 - 1999/06 がん研究振興財団 研究員・ポスドク
- 1992/04 - 1995/03 東レ株式会社
Show all
Committee career (1): Association Membership(s) (2): Return to Previous Page