Rchr
J-GLOBAL ID:200901000315656140   Update date: Nov. 16, 2024

Araki Norie

アラキ ノリエ | Araki Norie
Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): http://srv02.medic.kumamoto-u.ac.jp/dept/tumor/index.html
Research field  (5): Genomics ,  Tumor biology ,  Pathobiochemistry ,  Functional biochemistry ,  Medical biochemistry
Research keywords  (7): PROTEINCHEMISTRY ,  BIOCHEMISTRY ,  Hepatic cancer ,  Neural tumor ,  Cancer Stem Cell ,  Proteomics ,  Tumor Genetics and BIology
Research theme for competitive and other funds  (164):
  • 2023 - 2026 Elucidation of transcription control mechanism by the intrinsically disordered proteins
  • 2024 - 2025 Elucidation of intracellular and extracellular signals involved in abnormal neural differentiation and tumorigenesis in neurofibromatosis and development of therapeutic strategies
  • 2022 - 2025 神経線維腫症の神経系細胞異常分化と腫瘍化の責任因子シグナルと治療標的の解明
  • 2022 - 2024 Target screening for cancer stem cells by a novel integrated N-terminomics and phospho- proteomics
  • 2021 - 2024 Identification of tumor-specific antigens to construct the novel combination immunotherapy
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Papers (136):
  • Takumi Yamamoto, Arisu Furukawa, Yue Zhou, Nobuaki Kono, Shojiro Kitajima, Hiroto Ohguchi, Yawara Kawano, Shingo Ito, Norie Araki, Sumio Ohtsuki, et al. Increased CSN5 expression enhances the sensitivity to lenalidomide in multiple myeloma cells. iScience. 2024. inpress
  • Shujiro Okuda, Akiyasu C. Yoshiza, Daiki Kobayashi, Yushi Takahashi, Yu Watanabe, Yuki Moriya, Atsushi Hatano, Tomoyo Takami, Masaki Matsumo, Norie Araki, et al. jPOST environment accelerates the reuse and reanalysis of public proteome mass spectrometry data. Nucleic Acids Research. 2024. 1-7
  • Tsuyoshi Tabata, Akiyasu C Yoshizawa, Kosuke Ogata, Chih-Hsiang Chang, Norie Araki, Naoyuki Sugiyama, Yasushi Ishihama. UniScore, a unified and universal measure for peptide identification by multiple search engines. bioRxiv,. 2024
  • Akiko Niibori-Nambu, Yoshimune Yamasaki, Daiki Kobayashi, Kiyohiko Angata, Atsushi Kuno, Orasa Panawan, Atit Silsirivanit, Hisashi Narimatsu, Norie Araki. Chondroitin sulfate modification of CSPG4 regulates the maintenance and differentiation of glioma-initiating cells via integrin-associated signaling. Journal of Biological Chemistry. 2024. 300. 3. 105706-105706
  • Chutima Talabnin, Thanawat Trasaktaweesakul, Pitchanun Jaturutthaweechot, Pundit Asavaritikrai, Dusit Kongnawakun, Atit Silsirivanit, Norie Araki, Krajang Talabnin. Altered O-linked glycosylation in benign and malignant meningiomas. PeerJ. 2024. 12. e16785-e16785
more...
MISC (202):
  • 高橋悠志, 吉沢明康, 小林大樹, 守屋勇樹, 幡野敦, 高見知代, 松本雅記, 荒木令江, 田畑剛, 田畑剛, et al. Accelerating data re-analysis in jPOST using metadata from JPDM data papers. 日本プロテオーム学会大会プログラム・抄録集. 2024. 2024 (Web)
  • Hideaki Naoe, Takehisa Watanabe, Katsuya Nagaoka, Nahoko Fujimoto, Norie Araki, Jiro Fujimoto, Motohiko Tanaka, Yutaka Sasaki. MULTI-OMICS ANALYSES IDENTIFY NUCLEOPHOSMIN AS A KEY REGULATOR OF APOPTOSIS RESISTANCE IN HUMAN HEPATOCELLULAR CARCINOMA. HEPATOLOGY. 2019. 70. 562A-562A
  • Norie Araki, Akiko Namubu Niibori, Daiki Kobayashi, Takuichiro Hide, Hideo Nakamura, Junichi Kuratsu. Integrated phospho-glyco-proteogenomics identified the potential clinical target signals against glioma stem cells. CANCER SCIENCE. 2018. 109. 656-656
  • Diwakar Guragain, Norie Araki, Atit Silsinivanit, Wunchana Seubwai, Ubon Cha'on. ANTI-MALARIAL DRUGS ARTESUNATE AND CHLOROQUINE INDUCE CELL DEATH BY DIFFERENT MECHANISMS IN BILE DUCT CANCER CELL LINES. ANTICANCER RESEARCH. 2018. 38. 3. 1830-1830
  • Norie Araki, Akiko N. Nambu, Atit Silsirivanit, Hiroki Okanishi, Daiki Kobayashi, Takuichiro Hide, Hideo Nakamura. Studies of key signals related to the maintenance and differentiation of glioma initiating cells by integrated-omics. CANCER SCIENCE. 2018. 109. 630-630
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Patents (10):
Books (38):
  • プロテオミクス辞典
    講談社 2013
  • 神経線維腫症2型,母斑と母斑症,皮膚科臨床アセット15
    中山書店 2013
  • 融合プロテオミクスによる病態メカニズムの解析『創薬のためのタンパク質・プロテオミクス解析』
    羊土社 2010
  • 疾患プロテオミクスの最前線 : プロテオミクスで病気を治せるか
    メディカルドゥ 2005 ISBN:4944157320
  • 「in vitroラベル法」オンラインLC-MS法による発現プロファイル解析
    “決定版!プロテオーム解析マニュアル" 磯辺俊明・高橋信弘編集, 羊土社 2004
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Lectures and oral presentations  (151):
  • Construction of Japan Proteome Standard Repository/Database
    (jPOST 2016)
  • Extraction and validation of the specific signal network in cancer tissue cells by proteomics-based integrated -omics
    (2015)
  • Identification of TCTP-mTOR signaling as a novel biological target for Neurofibromatosis Type 1-associated tumors
    (2015)
  • The frontier of proteomics-based life science and its clinical application.
    (2015)
  • Proteome-Centric Approaches to Decipher Biological Functions
    (15th Annual International Proteomics Conference 2015)
more...
Works (31):
  • プロテオミクス解析による創薬ターゲットの探索
    2013 - 2015
  • 融合プロテオミクス統合マイニングソフトweb application
    2011 -
  • 最先端解析技術によるがんの体系的プロテオミクス研究戦略
    2005 - 2010
  • 脳神経系特異的な虚血性細胞死の分子シグナル制御機構の解明
    2006 - 2007
  • 悪性脳腫瘍関連遺伝子h-neuの機能解析とそれを応用した分子標的治療の開発
    2005 - 2007
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Education (3):
  • 1987 - 1992 熊本大学大学院研究員 (医学博士)
  • 1982 - 1984 Graduate School Kyushu University
  • 1978 - 1982 Kyushu University
Professional career (1):
  • 医学博士 (熊本大学)
Work history (13):
  • 2007 - 現在 Kumamoto University Graduate School of Medical Sciences Associate Professor
  • 2010 - Associate Professor,Faculty of Life Sciences(Basic medicine group),Kumamoto University
  • 2006 - 2007 Kumamoto University Graduate School of Medical Sciences Associate Professor
  • 2006 - 2007 Associate Professor,
  • 2003 - 2006 Kumamoto University School of Medicine Associate Professor
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Committee career (10):
  • 2020 - 現在 International Human Proteome Organization executive board member
  • 2018 - 現在 日本プロテオーム学会 理事
  • 2015 - 2016 日本ブロテーム学会/日本ヒトプロテオーム機構学術総会 学会年会長
  • 2009 - 2014 日本プロテオーム学会 理事
  • 2002 - 2014 日本ヒトプロテオーム機構 理事
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Awards (19):
  • 2024/09 - 日本癌学会 女性がん研究者シンポジウムベスト発表賞
  • 2022/11 - タイ国立コンケン大学 名誉博士号学位授与 分子生物学医学生化学分野の長年の貢献に対する名誉博士号学位
  • 2022 - Kumamoto University Kumamoto University Award for Education
  • 2018 - 熊本大学 熊本大学研究奨励賞
  • 2017/07 - Japan Proteome Organization Academic Aword Application of integrated proteomics for cancer research
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Association Membership(s) (13):
国際プロテオーム学会(IPPC) ,  The protein society ,  米国生物学会(FASEB) ,  Methods in Protein Structure Analysis(MPSA) ,  日本プロテオーム学会 ,  The protein society ,  JAPAN SOCIETY OF CLINICAL PROTEOGENOMICS ,  JAPANESE SOCIETY FOR BIOMEDICAL MASS SPECTROMETRY ,  PROTEIN SCIENCE SOCIETY OF JAPAN ,  THE JAPANESE CANCER ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  International Human Proteome Organization
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