- 2015 - 2018 Development of Thermal Refolding and application for antibody production
- 2012 - 2015 Structural characterization of L-amino acid oxidase with high substrate specificity and industrial applications
- 2009 - 2011 Development of thermostable protein-refolding catalysis and characterization of the kinetic properties
- 2006 - 2008 Studies on Isozymes of Human Lung Selenophosphate Synthetase
- 2006 - 2007 Structural and functional analysis of anti-tumor microbial enzymes and their application for development of next generation anti-tutor enzymes.
- 2002 - 2004 Structure and fanctional analysis of NAD^+-dependent isocitrate dehydrogenase from the chemolithotroph Aci dithiobacillus thiooxidans
- 2002 - 2003 Preparation and characterization of sinefungin synthetase
- 2001 - 2002 Dynamism of activated-selenium species: Structural biological analysis of mechanism of biosynthesis of selenium-containing proteins
- 2001 - 2001 新規抗腫瘍性酵素の開発と癌治療への応用
- 1999 - 2001 Purification and Molcular Cloning of Sinefungin synthetase fom Streptomyces incarnatus NRRL8089.
- 1999 - 2000 チオレドキシン還元酵素のセレノシステイン残基の触媒機能
- 1998 - 2000 ANALYSIS OF SUBSTRATE RECOGNITION MECHANISM OF ISOPROPYLMALATE DEHYDROGENASE
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