Inanami Osamu

2019 - 2022 Development of a method of 3D oxygen and pH mapping of tumors using electron spin resonance spectroscopy

2019 - 2022 Development of a novel radiotherapy targeting iron-dependent cell death ferroptosis

2018 - 2022 Elucidation of pathological pain via nociceptors and its application to pain relief

2019 - 2021 Development of a MS imaging-based diagnosis for novel cancer senotherapy

2018 - 2021 Analysis of radioresistance factors of tumors in radiotherapy by using MS imaging and ESR imaging techniques

2019 - 2021 がん特異的グルタミン代謝とアセテート代謝を標的とした新規がん治療法の開発

2018 - 2020 Sono-mechanotherapy for neurite outgrowth

2016 - 2020 Development of the optimal medication for individuals exposed to lethal radiation

2014 - 2017 次世代放射線治療の最適化のための新規機能イメージング技術による基盤研究

2014 - 2015 腫瘍転移巣の術中迅速診断を目標とした新規近赤外発光イメージング技術の開発

2011 - 2015 Role of functional change of microglia in neuropathogenesis of prion diseases

2012 - 2014 Risk-communication of exposure to radioacive contaminants after the Great East Japan Earthquake disaster

2012 - 2012 Characterization of malignant glioma and development of potent treatment strategy focusing on hypoxia dynamics

2010 - 2012 Cellular and Immune Responses of Dairy Cows Induced by Intramammary Infusion of Lactic Acid Bacteria and Therapeutic Trials to Quarters of Cows with Mastitis.

2009 - 2011 Structural analysis of zoonosis-related high-molecular protein aggregation by double electron-electron resonance (DEER) technique

2009 - 2010 膜透過性ペプチド融合アポトーシス誘導タンパク質を用いた新規放射線がん治療

2007 - 2009 From the ER to the plasma membrane : Vesicular transport of membrane skeleton units and the diseases

2006 - 2009 Elucidation of the mechanism on the formation of early pathological lesion of prion diseases

2006 - 2009 Regulatory mechanisms of vanilloid receptor on pain signaling

2007 - 2008 Molecular imaging of prion protein by atomic force microscop yand a novel electro-spin-resonance techniques

2006 - 2008 Placental/Umbilical cord blood-derived mesenchymal stem cell-likestroma cells support the hematopoietic recovery of X-irradiated human CD34+ cells

2006 - 2007 プリオンと銅イオン相互作用の新しいパルス電子スピン共鳴法を用いたアプローチ

2005 - 2007 Immunological and molecular analysis of responses of mammary gland against infection and modulation of the immunological functions in dairy cows

2005 - 2006 Structural analysis of prion proteins and mechanism of PrPsc transition by using a novel dynamic molecular structure analysis

2005 - 2006 実験動物頭部のファンクショナルMRIによる痛覚のビジュアリゼーション

2004 - 2006 Molecular pathology for down-regulation of erythroid-specific genes in prion diseases

2004 - 2006 Hierarchical Correlation Dynamics among Cellular Rhythms: Coordination and Dissociation of Non-linear Biological Oscillators.

2004 - 2006 Does the bovine lactoferrin improve chronic inflammation in the immuno-suppressive condition induced by FIV infection?

2004 - 2006 神経因性疼痛発生の分子機構の解明と痛覚評価系の開発に関する研究

2003 - 2005 Role of store-operated Ca entry mechanism in signal transduction in gastrointestinal intrinsic neurons

2003 - 2004 Dysfunction of neutrophil during parturition and proteome analysis of placenta and serum in cow

2002 - 2004 Characterization of host defence capability of dairy cows during peripartum period and modulation of the immunological functions.

2002 - 2003 抗酸化物質を用いた新たな神経突起・神経細胞分化誘導法の開発

2002 - 2003 Molecular mechanisms for the assembly of the red cell membrane skeleton during erythroid cell development

2001 - 2002 Analysis for putative relationship between causative genes for hereditary disorder and quantitative traits loci in cattle

2001 - 2002 ネコ免疫不全FIVの抗酸化剤治療の基礎的検討と臨床応用

2000 - 2002 Hormonal system for regulating local defense

2001 - 2001 NADPHオキシダーゼコンポーネントp47^<phox>のSH3Aドメインの構造解析 -部位特異的スピンラベル法と飽和移動法による研究-

2001 - 2001 新規ヌクレオシド系制ガン剤と放射線照射併用によるアポトーシス細胞死増感作用

2000 - 2001 Development of antitumor drugs to enhance apoptotic cell death and clinical application

2000 - 2001 Development of new antitumor drugs and apoptotic signal transudation - Application to feline leukemia and canine lymphoma -

2000 - 2001 Molecular mechanism for the assembly of red cell membrane skeletons based on pathobiology of congenital hemolytic anemia in cattle

2000 - 2001 Action of optimum cytokine for the recovery of X-irradiated human hematopoietic stem and progenitor cells

1999 - 2001 Characterization of CD18-Deficient Neutrophil Functions and Some Modulations of Bovine Neutrophils from Cattle with Bovine Leukocyte Adhesion Deficiency

2000 - 2000 部位特異的スピンラベル法を用いたオキシダーゼ活性化と蛋白構造変化に関する研究-p47phoxのリン酸化による構造変化とその細胞膜への移動との関連性-

1997 - 1998 Clonic granulomaous disease (CGD) and its deficients in bactricidal activity-Basic research for gene therapy for CGD-

1997 - 1998 The defect of biodefense mechanisms in bovine leukocyte adhesion deficiency syndrome (BLAD) as observed from signal transduction pathway

1997 - 1998 Steric visualization of diseased organs of laboratory small animals by three-dimensionally reconstructing MRI method

1997 - 1998 Pathobiology of leukocyte functions from cattle with leukocyte adhesion deficiency(BLAD)and trials of bone marrow transplantation to BLAD-cattle.

1996 - 1997 Fundamental studies on the molecular therapy for botulisms

1996 - 1996 好中球NADPHオキシダーゼの解析と活性酸素生成機構-慢性肉芽腫症の遺伝子治療の基礎的解析-

1995 - 1996 Spin-trapping detection of nitric oxide (NO) production from macrophage during matuation

1995 - 1995 嗅球におけるNO合成酵素およびMAPキナーゼ発現の分子制御機構-免疫組織化学、in situ PCR hybridizationならびにノーザン・ブロッティング法による解析

1995 - 1995 ボツリヌス中毒症の分子治療法に関する基礎的研究

1994 - 1994 成牛ならび新生子牛の多核白血球の活性酸素産生機構解明に関する研究

1994 - 1994 嗅覚系におけるプログラム細胞死の発現動態とその分子制御機構-遺伝子組織化学,免疫組織化学ならびにレクチン組織化学的による解析

1988 - 1989 Regulation of cerebral blood flows by cholinergic fibers originating in the nucleus basalis of Meynert.