Nagamitsu Tohru

ナガミツトオル | Nagamitsu Tohru

Affiliation and department：
Job title：教授
Homepage URL (1)： https://www.pharm-kitasato-u-orgsyn.com

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (1)：天然物化学

Research theme for competitive and other funds (9)：

2022 - 2025 位置選択的なヨード環化反応を鍵反応とするフサリシドの不斉合成研究
2014 - 2017 Synthetic study of habiterpenol
2010 - 2012 Total synthesis and structure-activity relationship study of pyripyropene A, a potent and selective ACAT2 Inhibitor
2009 - 2011 THE CHEMICAL BIOLOGY OF NEW MICROBIAL ANTI-INFECTIVE AGENTS
2006 - 2008 Discovery and development of selectivity-defined inhibitors toward two acyl-CoA : cholesterol acyltransferase isozymes

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Papers (87)：

Hanaka Satoh, Daiki Lee, Shiho Arima, Kanji Hosoda, Satoru Shigeno, Hiroshi Tomoda, Taichi Ohshiro, Tohru Nagamitsu. Total syntheses of mavintramycin A and its structural analog, cytosaminomycin C, and evaluation of their antibacterial activities against Mycobacterium avium and Mycobacterium intracellulare. Tetrahedron. 2024. 134299-134299
Ayuki Nakano, Akane Morita, Shiho Arima, Tohru Nagamitsu, Tsutomu Nakahara. Role of mammalian target of rapamycin in the formation and progression of retinopathy of prematurity-like vascular abnormalities in neonatal rats. Microvascular research. 2024. 152. 104626-104626
Kotaro Tanaka, Shou Suzuki, Daiki Lee, Shiho Arima, Satoshi Ohte, Taichi Ohshiro, Ryuji Uchida, Hiroshi Tomoda, Tohru Nagamitsu. Total synthesis of tanzawaic acid A. Tetrahedron. 2023. 133556-133556
Haruki Taguchi, Mayuko Kawaguchi, Tohru Nagamitsu, Masaki Ohtawa. Concise syntheses of (-)-habiterpenol and (+)-2,3-<i>epi</i>-habiterpenol <i>via</i> redox radical cyclization of alkenylsilane. Organic & Biomolecular Chemistry. 2023
Daiki Lee, Takuya Tokizaki, Shiho Arima, Tohru Nagamitsu. Total syntheses of furopyridones CJ-16,170 and 2-epi-CJ-16,169. Tetrahedron Letters. 2022. 154095-154095

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MISC (10)：

森田茜, 宮永香純, 浅野大樹, 有馬志保, 森麻美, 森麻美, 坂本謙司, 坂本謙司, 長光亨, 中原努. The Visualization of ERK Activity at the Vascular Front in the Neonatal Mouse Retina. 眼薬理. 2021. 35. 1
Keisuke Kobayashi, Ryuji Uchida, Takashi Fukuda, Tohru Nagamitsu, Kenichiro Nagai, Hiroshi Tomoda. The study of non-antibiotics potentiating antifungal amphotericin B activity from microbial origins. Kagaku Kogyo. 2021. 72. 1. 28-37
Takashi Fukuda, Nobuhiro Koyama, Kenta Shimoyama, Tohru Nagamitsu, Hiroshi Tomoda. Study on inhibitors of yellow pigment production in Staphylococcus aureus. Kagaku Kogyo. 2016. 67. 9. 687-695
大多和正樹, 大村智, 供田洋, 長光亨. Design and synthesis of A-ring truncated pyripyropene A analogs as potent ACAT2 selective inhibitors. Medchem News. 2014. 24. 3. 25-31
Masaki Ohtawa, Satoshi Omura, Hiroshi Tomoda, Tohru Nagamitsu. Structure-activity relationship study and total synthesis of pyripyropene A as a potent ACAT2-selective inhibitor. Yuki Gosei Kagaku Kyokaishi. 2013. 71. 8. 830-843

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Lectures and oral presentations (25)：

Tanzawaic acid Aの全合成研究
(日本薬学会関東支部大会講演要旨集 2021)
Total syntheses of CJ-16,170 and 2-epi-CJ-16,169 via the regioselective iodocyclization
(複素環化学討論会講演要旨集 2021)
骨分化阻害物質scopranoneとアミノ酸との反応
(日本薬学会年会要旨集 2020)
4-epi-Atpenin A5の全合成
(反応と合成の進歩シンポジウム講演要旨集 2019)
4'-epi-Atpenin A5の合成研究
(日本薬学会年会要旨集 2018)

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Professional career (2)：

Association Membership(s) (3)：

日本化学会 , 有機合成化学協会 , 日本薬学会

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