Nagamitsu Tohru

ナガミツトオル | Nagamitsu Tohru

Affiliation and department：
Job title：教授
Homepage URL (1)： https://www.pharm-kitasato-u-orgsyn.com

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (1)：天然物化学

Research theme for competitive and other funds (9)：

2022 - 2025 位置選択的なヨード環化反応を鍵反応とするフサリシドの不斉合成研究
2014 - 2017 Synthetic study of habiterpenol
2010 - 2012 Total synthesis and structure-activity relationship study of pyripyropene A, a potent and selective ACAT2 Inhibitor
2009 - 2011 THE CHEMICAL BIOLOGY OF NEW MICROBIAL ANTI-INFECTIVE AGENTS
2006 - 2008 Discovery and development of selectivity-defined inhibitors toward two acyl-CoA : cholesterol acyltransferase isozymes

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Papers (85)：

Kotaro Tanaka, Shou Suzuki, Daiki Lee, Shiho Arima, Satoshi Ohte, Taichi Ohshiro, Ryuji Uchida, Hiroshi Tomoda, Tohru Nagamitsu. Total synthesis of tanzawaic acid A. Tetrahedron. 2023. 133556-133556
Haruki Taguchi, Mayuko Kawaguchi, Tohru Nagamitsu, Masaki Ohtawa. Concise syntheses of (-)-habiterpenol and (+)-2,3-<i>epi</i>-habiterpenol <i>via</i> redox radical cyclization of alkenylsilane. Organic & Biomolecular Chemistry. 2023
Daiki Lee, Takuya Tokizaki, Shiho Arima, Tohru Nagamitsu. Total syntheses of furopyridones CJ-16,170 and 2-epi-CJ-16,169. Tetrahedron Letters. 2022. 154095-154095
Miyuki Konya, Shiho Arima, Daiki Lee, Masaki Ohtawa, Kenta Shimoyama, Takashi Fukuda, Ryuji Uchida, Hiroshi Tomoda, Noriyuki Yamaotsu, Nobutada Tanaka, et al. Synthesis and Evaluation of Habiterpenol Analogs. Chemical and Pharmaceutical Bulletin. 2022. 70. 4. 261-268
Manahito Aoki, Midori Naya, Shiho Arima, Kaori Shinohara, Masahiro Kato, Kiyoshi Shibuya, Masaki Ohtawa, Tohru Nagamitsu, Katsuya Otori. Mixture of clopidogrel bisulfate and magnesium oxide tablets reduces clopidogrel dose administered through a feeding tube. Journal of Pharmaceutical Health Care and Sciences. 2021. 7. 1. 18-25

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MISC (10)：

森田茜, 宮永香純, 浅野大樹, 有馬志保, 森麻美, 森麻美, 坂本謙司, 坂本謙司, 長光亨, 中原努. The Visualization of ERK Activity at the Vascular Front in the Neonatal Mouse Retina. 眼薬理. 2021. 35. 1
Keisuke Kobayashi, Ryuji Uchida, Takashi Fukuda, Tohru Nagamitsu, Kenichiro Nagai, Hiroshi Tomoda. The study of non-antibiotics potentiating antifungal amphotericin B activity from microbial origins. Kagaku Kogyo. 2021. 72. 1. 28-37
Takashi Fukuda, Nobuhiro Koyama, Kenta Shimoyama, Tohru Nagamitsu, Hiroshi Tomoda. Study on inhibitors of yellow pigment production in Staphylococcus aureus. Kagaku Kogyo. 2016. 67. 9. 687-695
大多和正樹, 大村智, 供田洋, 長光亨. Design and synthesis of A-ring truncated pyripyropene A analogs as potent ACAT2 selective inhibitors. Medchem News. 2014. 24. 3. 25-31
Masaki Ohtawa, Satoshi Omura, Hiroshi Tomoda, Tohru Nagamitsu. Structure-activity relationship study and total synthesis of pyripyropene A as a potent ACAT2-selective inhibitor. Yuki Gosei Kagaku Kyokaishi. 2013. 71. 8. 830-843

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Lectures and oral presentations (25)：

Tanzawaic acid Aの全合成研究
(日本薬学会関東支部大会講演要旨集 2021)
Total syntheses of CJ-16,170 and 2-epi-CJ-16,169 via the regioselective iodocyclization
(複素環化学討論会講演要旨集 2021)
骨分化阻害物質scopranoneとアミノ酸との反応
(日本薬学会年会要旨集 2020)
4-epi-Atpenin A5の全合成
(反応と合成の進歩シンポジウム講演要旨集 2019)
4'-epi-Atpenin A5の合成研究
(日本薬学会年会要旨集 2018)

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Professional career (2)：

Association Membership(s) (3)：

日本化学会 , 有機合成化学協会 , 日本薬学会

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