Rchr
J-GLOBAL ID:200901005265862160
Update date: Sep. 27, 2024
Saijo Masafumi
サイジョウ マサフミ | Saijo Masafumi
Affiliation and department:
Job title:
Associate Professor
Research field (1):
Molecular biology
Research keywords (7):
Nucleotide excision repair
, CSB
, CSA
, UVSSA
, XPA
, DNA修復
, Nuclear matrix
Research theme for competitive and other funds (19):
- 2020 - 2023 Functional analysis of Cockayne syndrome proteins in transcription-coupled nucleotide excision repair
- 2015 - 2018 Elucidation of molecular mechanism of transcription-coupled nucleotide excision repair
- 2012 - 2015 Analyses of nucleotide excision repair factors in the regulation of gene expression
- 2005 - 2009 Molecular genetic analysis of cellular response to transcription-blocking DNA damage and its defective disorders
- 2000 - 2004 転写とヌクレオチド除去修復機構を共役する新規蛋白質複合体の解析
- 1999 - 2001 Molecular genetics of human diseases with defect in transcription and DNA repair
- 1999 - 1999 DNA修復におけるXPAの機能と紫外線誘発皮膚発癌に伴う遺伝子変化の解析
- 1998 - 1998 DNA修復におけるXPA蛋白質の機能とその欠損による紫外線誘発皮膚発癌の解析
- 1996 - 1998 Molecular biology of nucleotide excision repair-deficient diseases
- 1997 - 1997 DNA除去修復におけるXPA蛋白質の機能解析
- 1996 - 1996 新規XPA結合蛋白質の解析
- 1996 - 1996 ヌクレオチド除去修復におけるXPA蛋白質の機能解析
- 1995 - 1996 Molecular Dissection of Human DNA Excision Repair Genes
- 1995 - 1995 DNA除去修復におけるXPA蛋白質の機能解析
- 1994 - 1995 Analysis of DNA repair functions of xeroderma pigmentosum gene
- 1994 - 1994 DNA除去修復における色素性乾皮症蛋白の相互作用の解析
- 1990 - 1990 細胞増殖におけるDNAトポイソメラーゼIIのリン酸化と活性の調節
- ヌクレオチド除去修復の分子機構
- Molecular mechanism of nucleotide excision and repair
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Papers (58):
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Ryo Sakasai, Mitsuo Wakasugi, Tadashi Matsui, Yumi Sunatani, Masafumi Saijo, Tsukasa Matsunaga, Kuniyoshi Iwabuchi. Camptothecin compromises transcription recovery and cell survival against cisplatin and ultraviolet irradiation regardless of transcription-coupled nucleotide excision repair. DNA Repair. 2022. 113. 103318-103318
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Alisha A Galande, Masafumi Saijo, Saroj S Ghaskadbi, Surendra Ghaskadbi. Xeroderma pigmentosum A homolog from Hydra partially complements DNA repair defect in human XPA-deficient cells. Journal of Biosciences. 2021. 46. 2. Article: 48
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Tomio S Takahashi, Yusuke Sato, Atsushi Yamagata, Sakurako Goto-Ito, Masafumi Saijo, Shuya Fukai. Structural basis of ubiquitin recognition by the winged-helix domain of Cockayne syndrome group B protein. Nucleic acids research. 2019. 47. 7. 3784-3794
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Galande AA, Perween N, Saijo M, Ghaskadbi SS, Ghaskadbi S. Analysis of the conserved NER helicases (XPB and XPD) and UV-induced DNA damage in Hydra. Biochimica et biophysica acta. General subjects. 2018. 1862. 9. 2031-2042
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Yooksil Sin, Futaba Makimura, Masafumi Saijo, Satoshi Obika. Generation of splice switching oligonucleotides targeting the Cockayne syndrome group B gene product in order to change the diseased cell state. Biochemical and Biophysical Research Communications. 2018. 500. 2. 163-169
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MISC (6):
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SIN Yooksil, SIN Yooksil, TANAKA Kiyoji, SAIJO Masafumi. 転写と共役した修復におけるCSBタンパク質の機能にはC末端領域とSUMO化が必要である. 日本生化学会大会(Web). 2015. 88th
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K. Sugasawa, Y. Okuda, M. Saijo, R. Nishi, Y. Shimizu, N. Matsuda, K. Tanaka, K. Tanaka, O. F. Hanaoka. Ubiquitylation of XPC protein by DDB-E3 complex. CELL STRUCTURE AND FUNCTION. 2004. 29. 11-11
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Tanaka Kiyoji, Horibata Katsuyoshi, Ren Yan, Kamiuchi Shinya, Saijo Masafumi, Yoshino Masafumi, Nakatsu Yoshimichi, Murai Machiko, Enokido Yasushi, Inamura Naoko, et al. Repair of Chromosomal Damage : Transcription-Coupled DNA Repair and Its Disorders(Symposium : Manipulating Chromosomes)(Abstracts of the 52nd Annual Meeting of the Society of Chromosome Research) :. Chromosome science. 2001. 5. 4. 164-171
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西条 将文, 田中 亀代次. 色素性乾皮症(XP)原因遺伝子群 (がん遺伝子研究の展望-2-). 現代化学増刊. 1997. 33. 135-142
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Kuraoka Isao, Saijo Masafumi, Nakatsu Yoshimichi, Tanaka Kiyoji. Characterization of a XPA/RPAIERCC1 complex : Characterization of a XPA/RPAIERCC1 complex. Journal of radiation research. 1995. 36. 4. 369-369
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Education (1):
- - 1990 The University of Tokyo
Professional career (1):
Association Membership(s) (2):
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