Art

J-GLOBAL ID：201802285529944889   Reference number：18A0837660

Generation of splice switching oligonucleotides targeting the Cockayne syndrome group B gene product in order to change the diseased cell state

病気の細胞状態を変化させるためにCockayne症候群B遺伝子産物を標的とするスプライススイッチングオリゴヌクレオチドの生成【JST・京大機械翻訳】

Author (5)： Sin Yooksil (National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Saito-Asagi, Ibaraki, Osaka, 567-0085, Japan) ,  Makimura Futaba (National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Saito-Asagi, Ibaraki, Osaka, 567-0085, Japan) ,  Saijo Masafumi (Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka, 565-0871, Japan) ,  Obika Satoshi (National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Saito-Asagi, Ibaraki, Osaka, 567-0085, Japan) ,  Obika Satoshi (Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka, 565-0871, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 500  Issue： 2  Page： 163-169  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Cockayne syndrome (CS) is a se...

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Thesaurus term： mRNA ,  patient ,  *gene ,  gene expression ,  termination codon ,  Up-Regulation ,  allele ,  nonsense mutation ,  Mutation ,  sensitivity ,  mitochondrial function ,  Membrane Potential, Mitochondrial ,  homozygosity ,  transposable element ,  molecular genetic phenomenon ,  genome
Semi thesaurus term： transposable element ,  *Cockayne症候群 , 【Automatic Indexing@JST】

Author keywords (5)： DNA repair ,  Cockayne syndrome ,  UV sensitive syndrome ,  Antisense oligonucleotides ,  Exon skipping

JST classification (3)： Structure and chemistry of genes  (EC02020U) ,  Genetic variation  (EC01030Y) ,  Molecular genetics in general  (EC02010J)

Terms in the title (5)： 病気 ,  細胞 ,  Cockayne症候群 ,  遺伝子産物 ,  標的