Rchr
J-GLOBAL ID：200901007833363819   Update date: Nov. 19, 2024

Kajihara Yasuhiro

カジハラ ヤスヒロ | Kajihara Yasuhiro
Affiliation and department：
Osaka University Graduate School of Science

About Osaka University Graduate School of Science


Homepage URL  (2)： http://www.chem.sci.osaka-u.ac.jp/lab/kajihara/index.html ,  http://www.chem.sci.osaka-u.ac.jp/lab/kajihara/en_index.html
Research field  (2)： Bioorganic chemistry ,  Structural/physical organic chemistry
Research keywords  (2)： Organic Chemistry, Carbohydrate Chemistry, Protein Chemistry ,  Organic Chemistry
Research theme for competitive and other funds  (30)：
  • 2021 - 2026 New Synthetic Methods for Glycoproteins and the Integrated Approaches to Elucidate the Functions of Post-translational Modifications
  • 2021 - 2024 Evaluation of the effect of natural or unnatural glycosylation modes on the activity of glycoproteins
  • 2021 - 2022 Novel simi-synthetic methods for glycoproteins and approaches to elucidate the function of post-translational modifications
  • 2016 - 2021 Chemical Biology of ER related glycan modifications
  • 2016 - 2021 糖鎖構造の可変を可能にする糖タンパク質の精密半化学合成とその品質分析技術の開発
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Papers (106)：
  • Yuta Maki, Akihiro Manbo, Abe Junpei, Hiroki Nobutou, Kohtaro Hirao, Ryo Okamoto, Masayuki Izumi, Shusuke Yamanaka, Mitsutaka Okumura, Yasuhiro Kajihara. Harnessing Free Sulfate Groups in Glycosylation Reactions. Angewandte Chemie (International ed. in English). 2024. e202416743
  • Yasuhiro Kajihara, Yanbo Liu, Yuta Maki, Ryo Okamoto, Ayano Satoh, Yasuto Todokoro, Yurie Kanemitsu, Keito Otani. Uncovering a Latent Bioactive Interleukin-6 Glycoform. Angewandte Chemie International Edition. 2024
  • Tatsunari Akiyama, Yusuke Tanaka, Ryo Okamoto, Yasuhiro Kajihara, Masayuki Izumi. Isopeptide bond formation mediated by δ-selenolysine for chemical ubiquitination. Frontiers in Chemistry. 2023. 11
  • Yugoviandi P Mamahit, Yuta Maki, Ryo Okamoto, Yasuhiro Kajihara. Semisynthesis of homogeneous misfolded glycoprotein interleukin-8. Carbohydrate research. 2023. 531. 108847-108847
  • Kota Nomura, Ryo Okamoto, Yuta Maki, Ayumu Hayashibara, Toshifumi Takao, Tomoya Fukuoka, Eiji Miyoshi, Bradley L Pentelute, Yasuhiro Kajihara. Rapid Chemical Synthesis of Serine Protease Inhibitor Kazal-type 13 (SPINK13) Glycoform by a Combined Method with Glycan Insertion Strategy and Fast-Flow Fmoc SPPS. Chemistry (Weinheim an der Bergstrasse, Germany). 2023. 29. 42. e202300646
ｍore...
MISC (78)：
  • 岡本亮, 岡本亮, 真木勇太, 真木勇太, 佐藤あやの, 梶原康宏, 梶原康宏. Revisiting the function of glycans on glycoproteins in protein-protein interaction. 日本糖質学会年会要旨集. 2022. 41st
  • 佐藤あやの, 真木勇太, 川田一稀, 岡本亮, 梶原康宏. 糖タンパク質の細胞内逆行輸送の定量化. 日本生化学会大会(Web). 2022. 95th
  • 西川晴美, 上田南, 真木勇太, 真木勇太, 岡本亮, 岡本亮, 和泉雅之, 梶原康宏, 梶原康宏. Glycopeptide synthesis for construction of quaternary structure of IgG antibody Fc region. 日本糖質学会年会要旨集. 2022. 41st
  • 真木勇太, 佐藤あやの, 川田一希, 岡本亮, 梶原康宏. Chemical synthesis of glycosylated Cholera toxin B-subunit and its delivering into living cells. 日本糖質学会年会要旨集. 2021. 40th
  • 野村幸汰, 真木勇太, 真木勇太, 岡本亮, 岡本亮, 佐藤あやの, 梶原康宏, 梶原康宏. Homogeneous Glycoprotein Synthesis by Chemical Insertion of Glycan. 日本糖質学会年会要旨集. 2021. 40th
ｍore...
Patents (2)：
  • 糖鎖アスパラギンを有する糖ペプチドの製造方法および該糖ペプチド
  • 糖鎖アスパラギン誘導体の製造方法
Books (2)：
  • Glycobiophysics
    Springer 2018
  • Glycochemical synthesis
    Wiley 2016
Lectures and oral presentations  (8)：
  • N-Glycans on Proteins
    (E. Fischer memorial symposium "What would E Fischer do todays?", Berlin 2019)
  • Chemical Synthesis of homogeneous glycoprotein having triantennary glycan
    (Solid phase peptide synthesis, Australia 2019)
  • Semi-Synthesis of homogeneous glycoproteins
    (Australian peptide symposium 2019)
  • Function of N-glycan on protein
    (American Chemical Society national meeting 2019)
  • Function of N-glycan on protein
    (Chemical Protein synthesis, Berlin 2019)
ｍore...
Education (3)：
  • 1990 - 1993 Tokyo Institute of Technology Interdisciplinary Graduate School of Science and Engineering Life Chemistry
  • 1988 - 1990 Kanagawa University Graduate School of Engineering. Chemistry
  • 1984 - 1988 Kanagawa University Faculty of Engineering
Professional career (1)：
  • (BLANK)
Work history (5)：
  • 2009/04 - 現在 Osaka University Graduate School of Science Professor
  • 2007/04 - 2009/03 Yokohama City University Graduate School of Integrated Science Professor
  • 2001/04 - 2007/03 Yokohama City University Graduate School of Integrated Science Associate Professor
  • 1995/06 - 2001/03 Yokohama City University Faculty of Science Assistant Professor
  • 1993/04 - 1995/05 Japan Tobacco Inc Life Science Research laboratory PostDoc
Committee career (1)：
  • 2009/07 - 現在 日本糖質学会 理事
Awards (3)：
  • 2020/07 - :International Carbohydrate Organization Roy L Whistler Award :Synthesis of homogeneous glycoprotein and evaluation of glycan functions
  • 2014/03 - Chemical Society of Japan Award for creative research of Japanese chemical society Chemical Synthesis of homogeneous glycoproteins
  • 2002/08 - Japanese Society of carbohydrate Research Encouragement Awards of Japan Society of Carbohydrate Research Chemical and enzymatic synthesis of N-Glycan derivatives
Association Membership(s) (3)：
日本糖質学会 ,  アメリカ化学会 ,  日本化学会
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